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Long-term Follow up of Congenital Adrenal Hyperplasia Patients with Hyponatremia

Song JH, Lee KH, Kim SD, Cho BS

Congenital adrenal hyperplasia (CAH) caused by 21-hydroxylase deficiency is an autosomal recessive disease, which leads to cortisol and aldosterone deficiency and hyperandrogenism. Typical medical treatment includes oral glucocorticoid and mineralocorticoid...
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Renal Subcapsular Hematoma: A Consequence of Reperfusion Injury of Long Standing Renal Artery Stenosis

Kang KP, Lee S, Kim W, Han YM, Kang SK, Park SK

Renal artery stenosis is a cause of secondary hypertension which can be cured by surgical or radiological intervention such as percutaneous transluminal renal artery stent placement. In this case we...
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Pseudohyperphosphatemia in a Patient with Multiple Myeloma

Lee Y, Koo T, Yi JH, Choi JH, Han SW, Park IK, Kim HJ

Hyperphosphatemia is an unusual manifestation in patients with multiple myeloma without a significantly reduced glomerular filtration rate. Serum phosphate may be falsely elevated when a large amount of paraproteins is...
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Electrolyte and Acid-Base Disturbances Induced by Clacineurin Inhibitors

Lee CH, Kim GH

Nephrotoxicity is the most common and clinically significant adverse effect of calcineurin inhibitors. Cyclosporine and tacrolimus nephrotoxicity is manifested by both acute azotemia and chronic progressive renal disease and tubular...
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Electrolyte and Acid-Base Disturbances Associated with Non-Steroidal Anti-Inflammatory Drugs

Kim S, Joo KW

Inhibition of renal prostaglandin synthesis by non-steroidal anti-inflammatory drugs (NSAIDs) causes various electrolyte and acid-base disturbances including sodium retention (edema, hypertension), hyponatremia, hyperkalemia, and decreased renal function. Decreased sodium excretion...
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Antimicrobial-induced Electrolyte and Acid-Base Disturbances

Kim YW

Antimicrobials are one of the most widely prescribed classes of therapeutic agents. Although adverse effects of antimicrobials are generally minimal and reversible, serious sequelae can sometimes remain, such as unusual...
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Factors associated with Hypokalemia in Continuous Ambulatory Peritoneal Dialysis Patients

Kim HW, Chang JH, Park SY, Moon SJ, Kim DK, Lee JE, Han SH, Kim BS, Kang SW, Choi KH, Lee HY, Han DS

Hypokalemia is a frequent problem in patients on continuous ambulatory peritoneal dialysis (CAPD) and is affected by multiple factors. To evaluate factors associated with hypokalemia, we studied 68 patients on...
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Varying Dialysate Bicarbonate Concentrations in Maintenance Hemodialysis Patients Affect Post-dialysis Alkalosis but not Pre-dialysis Acidosis

Noh US, Yi JH, Han SW, Kim HJ

This study aimed to assess the effects of different dialysate bicarbonate concentrations in correcting acid-base imbalance in 53 stable hemodialysis patients in a university-hemodialysis unit. Three different bicarbonate concentrations were...
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Altered Regulation of 11beta-hydroxysteroid Dehydrogenase II in the Kidney of Rats with Experimental Hypertension

Kang SS, Kim SW, Lee JU

The present study was aimed at investigating the role of type II 11beta-hydroxysteroid dehydrogenase (IIbeta- HSD II) in the development of hypertension. Two-kidney, one-clip (2K1C), deoxycorticosterone acetate (DOCA)/salt, or NG-nitro-L-arginine...
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Immunolocalization of Protein Kinase C Isoenzymes alpha, betaI, betaII and gamma in Adult and Developing Rat Kidney

Kim WY, Lee GS, Kim YH, Park EY, Hwang JS, Kim H, Kim J

Protein kinase C (PKC) plays an important role not only in signal transduction mechanisms in various biological processes, but also in the regulation of growth and differentiation during development. We...
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Dysregulation of Renal Cyclooxygenase-2 in Rats with Lithium-induced Nephrogenic Diabetes Insipidus

Kwon TH

This study aimed to examine whether the expression of major prostaglandin E2 (PGE2) synthesis enzyme, cyclooxygenase-2 (COX-2), is changed in the kidneys of the rats with lithium-induced nephrogenic diabetes insipidus...
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Effects of Increased Uric Acid Intake on the Abundance of Urate-anion exchanger and Organic Anion Transporter Proteins in the Rat Kidney

Kim S, Lee CH, Kang CM, Kim GH

Renal handling of uric acid mainly occurs in the proximal tubule, and bidirectional transport of urate may involve apical absorption via the urate-anion exchanger (URAT1) and basolateral uptake via organic...
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Altered Regulation of type 3 Na+/H+ exchanger, type 1 Na+/HCO3- cotransporter, and Na+,K+-ATPase in the Kidney of Rats with Experimental Rhabdomyolysis

Ma SK, Bae EH, Lee JU, Kim SY, Kim SZ, Choi KC, Kim SW

Metabolic acidosis was shown to correlate with deterioration of renal function in patients with rhabdomyolysis. The present study was aimed to investigate whether the changes of type 3 Na+/H+ exchanger...
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