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Letter: Increased Serum Angiopoietin-Like 6 Ahead of Metabolic Syndrome in a Prospective Cohort Study (Diabetes Metab J 2019;43:521-9)

Kim JH

No abstract available.
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An Age of Sodium-Glucose Cotransporter-2 Inhibitor Priority: Are We Ready?

Seo JA

No abstract available.
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Response: Increased Serum Angiopoietin-Like 6 Ahead of Metabolic Syndrome in a Prospective Cohort Study (Diabetes Metab J 2019;43:521-9)

Namkung J, Park KS

No abstract available.
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Corrigenda: Table Correction. Nonalcoholic Fatty Liver Disease in Diabetes. Part I: Epidemiology and Diagnosis

Lee YH, Cho Y, Lee BW, Park CY, Lee DH, Cha BS, Rhee EJ

In this article, the description of one equation named “NAFLD liver fat score” in the Table 3 was miswritten.
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Contributing Factors to Diabetic Brain Injury and Cognitive Decline

Verma N, Despa F

The link of diabetes with co-occurring disorders in the brain involves complex and multifactorial pathways. Genetically engineered rodents that express familial Alzheimer's disease-associated mutant forms of amyloid precursor protein and...
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Regulation of Systemic Glucose Homeostasis by T Helper Type 2 Cytokines

Kang YE, Kim HJ, Shong M

Obesity results in an inflammatory microenvironment in adipose tissue, leading to the deterioration of tissue protective mechanisms. Although recent studies suggested the importance of type 2 immunity in an anti-inflammatory...
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Longitudinal Changes of Body Composition Phenotypes and Their Association with Incident Type 2 Diabetes Mellitus during a 5-Year Follow-up in Koreans

Kim HK, Lee MJ, Kim EH, Bae SJ, Choe J, Kim CH, Park JY

BACKGROUND: To elucidate longitudinal changes of complex body composition phenotypes and their association with incident type 2 diabetes mellitus. METHODS: A total of 17,280 (mean age, 48.1±8.2 years) Korean adults who...
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Effects of Dapagliflozin on Endothelial Function, Renal Injury Markers, and Glycemic Control in Drug-Naïve Patients with Type 2 Diabetes Mellitus

Kong SH, Koo BK, Moon MK

BACKGROUND: The study aimed to evaluate the effects of dapagliflozin and metformin on vascular endothelial function and renal injury markers. METHODS: This prospective, randomized, open-label, crossover study included drug-naïve patients with...
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Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus

Hwang YC, Jun JE, Jeong IK, Ahn KJ, Chung HY

BACKGROUND: The apolipoprotein B/A1 (apoB/A1) ratio is a stronger predictor of future cardiovascular disease than is the level of conventional lipids. Statin and ezetimibe combination therapy have shown additional cardioprotective...
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Dipeptidyl Peptidase-4 Inhibitors versus Other Antidiabetic Drugs Added to Metformin Monotherapy in Diabetic Retinopathy Progression: A Real World-Based Cohort Study

Chung YR, Ha KH, Kim HC, Park SJ, Lee K, Kim DJ

BACKGROUND: To investigate the effects of dipeptidyl peptidase-4 inhibitor (DPP4i) as add-on medications to metformin on progression of diabetic retinopathy (DR) in patients with type 2 diabetes mellitus, compared with...
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Mitochondrial Toxins and Healthy Lifestyle Meet at the Crossroad of Hormesis

Lee YM, Lee DH

Mitochondrial function is crucial for the maintenance of cellular homeostasis under physiological and stress conditions. Thus, chronic exposure to environmental chemicals that affect mitochondrial function can have harmful effects on...
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Efficacy and Safety of Sodium-Glucose Cotransporter-2 Inhibitors in Korean Patients with Type 2 Diabetes Mellitus in Real-World Clinical Practice

Hong AR, Koo BK, Kim SW, Yi KH, Moon MK

BACKGROUND: This study aimed to evaluate the efficacy and safety of sodium-glucose cotransporter-2 (SGLT2) inhibitors in Korean patients who had inadequately controlled type 2 diabetes mellitus (T2DM) in real-world clinical...
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Severity of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Mellitus: Relationship between Nongenetic Factors and PNPLA3/HSD17B13 Polymorphisms

Bellan M, Colletta C, Barbaglia , Salmi L, Clerici R, Mallela VR, Castello L, Saglietti , Carnevale Schianca GP, Minisini R, Pirisi M

BACKGROUND: The prevalence of nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (T2DM) is high, though its severity is often underestimated. Our aim is to provide...
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Essential Role of Protein Arginine Methyltransferase 1 in Pancreas Development by Regulating Protein Stability of Neurogenin 3

Lee K, Kim H, Lee J, Oh CM, Song H, Kim H, Koo SH, Lee J, Lim A, Kim H

BACKGROUND: Protein arginine methyltransferase 1 (PRMT1) is a major enzyme responsible for the formation of methylarginine in mammalian cells. Recent studies have revealed that PRMT1 plays important roles in the...
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Progression to Gestational Diabetes Mellitus in Pregnant Women with One Abnormal Value in Repeated Oral Glucose Tolerance Tests

Kang S, Kim MH, Kim MY, Hong JS, Kwak SH, Choi SH, Lim S, Park KS, Jang HC

BACKGROUND: Women with one abnormal value (OAV) in a 100 g oral glucose tolerance test (OGTT) during pregnancy are reported to have an increased risk of adverse pregnancy outcomes. However,...
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PF-04620110, a Potent Antidiabetic Agent, Suppresses Fatty Acid-Induced NLRP3 Inflammasome Activation in Macrophages

Jo SI, Bae JH, Kim SJ, Lee JM, Jeong JH, Moon JS

BACKGROUND: Chronic inflammation has been linked to insulin resistance and type 2 diabetes mellitus (T2DM). High-fat diet (HFD)-derived fatty acid is associated with the activation of chronic inflammation in T2DM....
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Low-Normal Free Thyroxine Levels in Euthyroid Male Are Associated with Prediabetes

Kim SW, Jeon JH, Moon JS, Jeon EJ, Kim MK, Lee IK, Seo JB, Park KG

Abnormal thyroid function is associated with impaired glucose homeostasis. This study aimed to determine whether free thyroxine (FT4) influences the prevalence of prediabetes in euthyroid subjects using a cross-sectional survey...
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Low-Frequency Intermittent Hypoxia Suppresses Subcutaneous Adipogenesis and Induces Macrophage Polarization in Lean Mice

Wang Y, Lee MY, Mak JC, Ip MS

BACKGROUND: The relationship between obstructive sleep apnoea (OSA) and metabolic disorders is complex and highly associated. The impairment of adipogenic capacity in pre-adipocytes may promote adipocyte hypertrophy and increase the...
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The Association between Z-Score of Log-Transformed A Body Shape Index and Cardiovascular Disease in Korea

Chung W, Park JH, Chung HS, Yu JM, Moon S, Kim DS

BACKGROUND: In order to overcome the limitations of body mass index (BMI) and waist circumference (WC), the z-score of the log-transformed A Body Shape Index (LBSIZ) has recently been introduced....
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Association between Change in Alcohol Consumption and Metabolic Syndrome: Analysis from the Health Examinees Study

Choi S, Kim K, Lee JK, Choi JY, Shin A, Park SK, Kang D, Park SM

BACKGROUND: The association between change in alcohol intake and metabolic syndrome is unclear. METHODS: This retrospective cohort consisted of 41,368 males and females from the Health Examinees-GEM study. Participants were divided...
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