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Effectiveness of premedication and rapid desensitization in hypersensitivity to L-asparaginase

Yoon DH, Kang SH, Kim HS, Lee JW, Yoon JS, Chung NG, Cho B

PURPOSE: L-asparaginase is a crucial chemotherapeutic agent for the treatment of acute lymphoblastic leukemia. However, hypersensitivity to L-asparaginase is common which limits its clinical use. METHODS: We performed 44 cases of...
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Rapid desensitization to isoniazid and rifampin in an adolescent with active pulmonary tuberculosis

Lee H, Kim MS, Yang HK, Kim M, Lee JY, Kim JM, Kang JM, Kim YJ, Ahn K, Kim J

Hypersensitivity reactions to antituberculosis medicine are obstacles to the treatment of tuberculosis. However, rapid drug desensitization can secure successful treatment with essential antituberculosis medicines in pediatric patients. A 17-year-old boy...
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Successful desensitization of a patient with albumin hypersensitivity

Jung SY, Choi YJ, Lee SH, Kang HR, Suh DI

There have been few cases of albumin hypersensitivity reported, and there is limited information on this condition. When a patient is anaphylactic to a certain drug and no alternative drug...
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Successful desensitization of pemetrexed-induced anaphylaxis in a patient with malignant mesothelioma

Youk J, Park H, Jin KN, Moon HJ, Yang MS, Kim KH, Kim JS

No abstract available.
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Successful desensitization for cytarabine induced anaphylaxis

Lee HW, Park JY, Moon JH, Park KT, Park HK, Kang HR

Cytarabine is a very important chemotherapeutic agent for leukemia and lymphoma patients and is prescribed more frequently than before. Cytarabine-induced delayed-onset hypersensitivity may rarely present as non-IgE mediated anaphylaxis. However,...
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Successful sequential desensitization in a patient with drug hypersensitivity to three kinds of antiplatelet agents

Kim GW, Kang SY, Sohn KH, Kim SH, Cho SH, Min KU, Chang YS

Antiplatelet agents, such as aspirin, clopidogrel, and cilostazol, are essential for the treatment and prevention of cardiovascular, cerebrovascular, and peripheral vascular diseases. A 53-year-old male with aspirin hypersensitivity developed dizziness,...
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A case of rapid desensitization for rituximab-induced delayed hypersensitivity reaction

Lee SH, Lee JH, Kim NH, Kang DY, Lee JY, Chung SJ, Oh JH, Kang HR

Rituximab is a monoclonal antibody used for the treatment of B-cell malignancies, including diffuse large B-cell lymphoma. Infusion-related hypersensitivity reactions to rituximab is well known, and delayed hypersensitivity reactions to...
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Successful rapid desensitization for cetuximab-induced anaphylaxis

Won HK, Moon SD, Shim JS, Chung SJ, Kim GW, Kim SJ, Park HK, Kang HR

Cetuximab, a chimeric mouse-human immunoglobulin, is an antiepidermal growth factor receptor monoclonal antibody. It has been approved by the U.S. Food and Drug Administration for the treatment of metastatic colorectal...
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Allergen immunotherapy

Park HS

  • KMID: 1927508
  • Korean J Med.
  • 2002 Mar;62(3):244-249.
No absract available.
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Updates on desensitization for hypersensitivity reactions related to chemotherapy

Lee SY, Yang MS, Jung JW, Oh MJ, Park CH, Sohn SW, Kang HR, Cho YJ, Korean Academy of Asthma Allergy and Clinical Immunology Drug Allergy Workgroup

As the use of chemotherapeutic agents increased rapidly in recent years, more patients are under the potential risk of chemotherapy related adverse reactions. Multiple regular exposures to the same drug...
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Successful desensitization of trimethoprim-sulfamethoxazole in Stenostrophomonas maltophilia osteomyelitis

Kim S, Lim KH, Kang MG, Park HK, Cho SH, Min KU, Kim SH, Chang YS

Stenotrophomonas maltophilia is an emerging pathogen associated with morbidity and mortality in hospitalized patients. The treatment of S. maltophilia infection is challenging because clinical isolates are frequently resistant to most...
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Successful rapid desensitization to trimethoprim-sulfamethoxazole-induced delayed hypersensitivity

Yoon D, Ahn H, Kim SY, Hwang SJ, Park HK, Kang HR

Trimethoprim-sulfamethoxazole (TMP-SMX) is an antibiotic used for the treatment or prophylaxis of Pneumocystis pneumonia and other infectious conditions. Sulfonamide derivatives have been reported to cause delayed hypersensitivity reactions, resulting in...
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Successful wheat-specific oral immunotherapy in highly sensitive individuals with a novel multirush/maintenance regimen

Pacharn P, Siripipattanamongkol N, Veskitkul , Jirapongsananuruk O, Visitsunthorn N, Vichyanond P

We reported a successful oral immunotherapy (OIT) in 2 children with high wheat sensitivity (4 and 14 years old boys). Oral challenges indicated eliciting doses of 300 mg, and wheat...
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A case of oral desensitization for hypersensitivity to exogenous progesterone

Kim YC, Choi KH, Kang DY, Sohn KH, Cho SH, Min KU, Kang HR

Hypersensitivity reaction to progesterone is a rare pathologic condition which consists of autoimmune response to endogenous progesterone, known as autoimmune progesterone dermatitis, and hypersensitivity reaction to exogenous progestogen. We report...
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Practice Patterns of Allergen Immunotherapy in Korea: Where Are We?

Lee JM

No abstract available.
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A Case of Change of Insulin-Specific Antibodies following Desensitization in Insulin Hypersensitivity Patients

  • KMID: 2146040
  • Korean J Asthma Allergy Clin Immunol.
  • 2010 Mar;30(1):63-67.
Although human insulin is widely used, insulin allergy is still an important issue. Desensitization is one of the strategies to overcome insulin allergy, but there are few report concerning the...
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A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel

Kyung SY, Cho YK, Kim YJ, Park JW, Jeong SH, Lee JI, Sung YM, Lee SP

Paragonimiasis is an infectious disease caused by trematodes of the genus Paragonimus. This trematode can be treated successfully with praziquantel in more than 90% of the cases. Although praziquantel is...
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Two Cases of Aspirin Sensitive, Intractable Chronic Urticaria Successfully Controlled by Aspirin Desensitization

  • KMID: 2299481
  • Korean J Asthma Allergy Clin Immunol.
  • 2012 Mar;32(1):51-55.
BACKGROUND: Chronic urticaria is a disease which is defined as hives with itching which waxed and waned for more than 6 weeks. In some cases, hives are intractable and refractory...
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Efficacy and Safety of Subcutaneous Allergen Immunotherapy for Allergic Rhinitis

Sohn MH

No abstract available.
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Oral antiplatelet agent hypersensitivity and cross-reactivity managed by successful desensitisation

Chin N, Rangamuwa , Mariasoosai R, Carnes J, Thien F

Oral platelet aggregation inhibitors are widely used for the treatment and prevention of cardiovascular diseases, including coronary stent thrombosis. Premature discontinuation following percutaneous coronary intervention would pose a grave risk...
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