- Effect of Creatine on the Survival of RGC-5 Cells under Serum Deprivation
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Kim JW, Hong JH, Kang SH, Kim YY
- KMID: 2214583
- J Korean Ophthalmol Soc.
- 2011 May;52(5):618-623.
- doi: 10.3341/jkos.2011.52.5.618
PURPOSE: To evaluate the protective effect of creatine on the survival of retinal ganglion cells after serum deprivation. METHODS: RGC-5 cells were exposed to 5 mM creatine with serum-free media for... -
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- The Interplay between Autophagy and Aging
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Pyo JO, Yoo SM, Jung YK
- KMID: 1965979
- Diabetes Metab J.
- 2013 Oct;37(5):333-339.
- doi: 10.4093/dmj.2013.37.5.333
Numerous studies have established a link between autophagy and aging; however, the relationship has not been clearly defined. Aging is a very complex process caused by the accumulation of various... -
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- NAD(P)H-quinone oxidoreductase-1 silencing modulates cytoprotection related protein expression in cisplatin cytotoxicity
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Park SR, Jung JY, Kim YJ, Jung DY, Lee MY, Ryu SY
- KMID: 2368736
- Korean J Vet Res.
- 2016 Mar;56(1):15-21.
- doi: 10.14405/kjvr.2016.56.1.15
NAD(P)H-quinone oxidoreductase-1 (NQO1) is a down-stream target gene of nuclear factor erythroid 2-related factor 2 (Nrf2), and performs diverse biological functions. Recently, NQO1 is recognized as an effective gene for... -
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- Understanding the Role of Heat Shock Protein Isoforms in Male Fertility, Aging and Apoptosis
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Purandhar , Jena PK, Prajapati , Rajput P, Seshadri S
- KMID: 2320775
- World J Mens Health.
- 2014 Dec;32(3):123-132.
- doi: 10.5534/wjmh.2014.32.3.123
Heat shock proteins (HSPs) play a role in the homeostasis, apoptosis regulation and the maintenance of the various other physiological processes. Aging is accompanied by a decrease in the resistance... -
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- Anti-diabetic effect of acid hydrolyzed silk peptides via cytoprotection of pancreas beta-cells and up-regulation of glucose uptake in muscle cells
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Joo SS
- KMID: 2055093
- J Biomed Res.
- 2013 Mar;14(1):28-34.
In this study, we observed anti-diabetic effects of acid hydrolyzed silk peptides, where the amount of peptides in the total amino acid mixture was strictly regulated. Using in vitro diabetes... -
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- The Role of Heat Shock Response in Insulin Resistance and Diabetes
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Kondo T, Motoshima , Igata M, Kawashima , Matsumura , Kai H, Araki E
- KMID: 2280700
- Diabetes Metab J.
- 2014 Apr;38(2):100-106.
- doi: 10.4093/dmj.2014.38.2.100
The expansion of life-style related diseases, such as metabolic syndrome (MS) and type 2 diabetes mellitus (T2DM), appears to be unstoppable. It is also difficult to cease their complications in... -
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- Effects and Mechanisms of Taurine as a Therapeutic Agent
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Schaffer S, Kim HW
- KMID: 2421732
- Biomol Ther.
- 2018 May;26(3):225-241.
- doi: 10.4062/biomolther.2017.251
Taurine is an abundant, β-amino acid with diverse cytoprotective activity. In some species, taurine is an essential nutrient but in man it is considered a semi-essential nutrient, although cells lacking... -
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- Rosmarinic Acid Attenuates Cell Damage against UVB Radiation-Induced Oxidative Stress via Enhancing Antioxidant Effects in Human HaCaT Cells
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Fernando P, Piao MJ, Kang KA, Ryu YS, Hewage SR, Chae SW, Hyun JW
- KMID: 2170544
- Biomol Ther.
- 2016 Jan;24(1):75-84.
- doi: 10.4062/biomolther.2015.069
This study was designed to investigate the cytoprotective effect of rosmarinic acid (RA) on ultraviolet B (UVB)-induced oxidative stress in HaCaT keratinocytes. RA exerted a significant cytoprotective effect by scavenging... -
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- Erythropoietin and autoimmune neuroinflammation: lessons from experimental autoimmune encephalomyelitis and experimental autoimmune neuritis
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Shin T, Ahn M, Moon C, Kim S
- KMID: 2133907
- Anat Cell Biol.
- 2012 Dec;45(4):215-220.
- doi: 10.5115/acb.2012.45.4.215
Erythropoietin (EPO) is known to have numerous biological functions. While its primary function is during haematopoiesis, recent studies have shown that EPO plays important role in cytoprotection, immunomodulation, and antiapoptosis.... -
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- Anti-Helicobacter pylori, Anti-apoptotic, and Cytoprotective Effects of Threonine Synthesized from Corynebacterium glutamicum in Gastric Epithelial Cells
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An JM, Kim YS, Hong YG, Hah BS, Sohn MS, Hahm KB
- KMID: 2469316
- Korean J Helicobacter Up Gastrointest Res.
- 2019 Dec;19(4):245-256.
- doi: 10.7704/kjhugr.2019.0011
BACKGROUND/AIMS: Among irritants causing gastric ulcer, Helicobacter pylori (H. pylori) might be pivotal, after which eradication became essential way in either inhibiting ulcerogenesis or preventing ulcer recurrence. Since threonine is... -
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- Melatonin Protects Human Adipose-Derived Stem Cells from Oxidative Stress and Cell Death
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Tan SS, Han X, Sivakumaran P, Lim SY, Morrison W
- KMID: 2403554
- Arch Plast Surg.
- 2016 May;43(3):237-241.
- doi: 10.5999/aps.2016.43.3.237
BACKGROUND: Adipose-derived stem cells (ASCs) have applications in regenerative medicine based on their therapeutic potential to repair and regenerate diseased and damaged tissue. They are commonly subject to oxidative stress... -
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- Low Dose Carbon Monoxide Inhalation Prevents Chronic Allograft Nephropathy following Kidney Transplantation in Rats. Heme Oxygenase-1 Derivatives Study I
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Yoon M
- KMID: 2211161
- J Korean Surg Soc.
- 2008 May;74(5):323-329.
PURPOSE: Carbon monoxide (CO), a product of heme catalysis by heme oxygenase (HO-1, HO-2, HO-3), induces cytoprotection against ischemia/reperfusion (I/R) injury in a variety of organs such as the heart,... -
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- Nitric Oxide-Induced Autophagy in MC3T3-E1 Cells is Associated with Cytoprotection via AMPK Activation
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Yang JY, Park MY, Park SY, Yoo HI, Kim MS, Kim JH, Kim WJ, Jung JY
- KMID: 2070790
- Korean J Physiol Pharmacol.
- 2015 Nov;19(6):507-514.
- doi: 10.4196/kjpp.2015.19.6.507
Nitric oxide (NO) is important in the regulation of bone remodeling, whereas high concentration of NO promotes cell death of osteoblast. However, it is not clear yet whether NO-induced autophagy... -
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- A1 Receptor-mediated Protection against Amyloid Beta-induced Injury in Human Neuroglioma Cells
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Cho YW, Jung HJ, Kim YK, Woo JS
- KMID: 1512906
- Korean J Physiol Pharmacol.
- 2007 Apr;11(2):37-43.
Adenosine has been reported to provide cytoprotection in the central nervous systems as well as myocardium by activating cell surface adenosine receptors. However, the exact target and mechanism of its... -
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- Selective Protection of Normal Proliferationg Cells Against Anti-Neoplastic Chemotherapy by Stausporine Pretreatment
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Jung SH, Kwon MK, Jo YS, Song MK, Ryu KS, Rha JG, Han KT
- KMID: 2272150
- Korean J Obstet Gynecol.
- 2003 Sep;46(9):1680-1692.
OBJECTIVE: A major limiting factor in human cancer chemotherapy is toxicity in normal cells and tissues. Our goal was to determine whether normal proliferating cells could be protected from chemotherapeutic... -
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- Loss of hsp70.1 Decreases Functional Motor Recovery after Spinal Cord Injury in Mice
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Kim HJ, Jung JI, Kim Y, Lee JS, Yoon YW, Kim J
- KMID: 2285397
- Korean J Physiol Pharmacol.
- 2010 Jun;14(3):157-161.
- doi: 10.4196/kjpp.2010.14.3.157
Heat shock proteins (HSPs) are specifically induced by various forms of stress. Hsp70.1, a member of the hsp70 family is known to play an important role in cytoprotection from stressful... -
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- Heme Oxygenase-1 via Transcriptional Activation of Nrf2 Attenuates Apoptosis in Lung Cancer Cells
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Kim HR, Kim EJ, Hwang KE, Kim SY, Park SH, Park JH, Kim HJ, Yang SH, Jeong ET
- KMID: 1881525
- J Lung Cancer.
- 2006 Jun;5(1):39-46.
- doi: 10.6058/jlc.2006.5.1.39
PURPOSE : Increasing evidences have indicated the critical role of HO-1 in cytoprotection and more diverse biological functions. HO-1 has been reported to stimulate tumor cell growth and proliferation. And... -
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- Association of Transforming Growth Factor-beta1 and Vascular Endothelial Growth Factor Gene Polymorphisms with Chronic Allograft Nephropathy and Graft Survival in Korean Renal Transplant Recipients
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Cho JH, Ryu HM, Jin MK, Chun JH, Hyun SH, Choi JY, Hur IK, Lee EY, Park SH, Kim YL, Kim CD
- KMID: 2253230
- Korean J Nephrol.
- 2008 Jul;27(4):465-475.
PURPOSE: Transforming growth factor-beta1 (TGF-beta1) has been associated with the promotion of renal allograft interstitial fibrosis and thereby chronic allograft nephropathy (CAN). Vascular endothelial growth factor (VEGF) has been shown... -
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- The Delayed Phase of Protection in Heat-Induced Preconditioning: Role of the Heat Shock Protein associated with cytoskeleton
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Kim DJ, Lee SY, Park JH, Hahn JH, Park SM, Jeong JS, Kim HD
- KMID: 2029592
- Korean Circ J.
- 2001 Oct;31(10):1049-1058.
- doi: 10.4070/kcj.2001.31.10.1049
BACKGROUND AND OBJECTIVES: We investigated the ability of a brief heat shock on day one to provide delayed protection against lethal heat stress on day two in a rat-derived H9c2... -
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- Anti-apoptotic effect of fermented Citrus sunki peel extract on chemical hypoxia-induced neuronal injury
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Ko WC, Lee SR
- KMID: 2209879
- J Nutr Health.
- 2015 Oct;48(5):451-456.
- doi: 10.4163/jnh.2015.48.5.451
PURPOSE: Neuronal apoptotic events induced by aging and hypoxic/ischemic conditions is an important risk factor in neurodegenerative diseases such as ischemia stroke and Alzheimer's disease. The peel of Citrus sunki... -
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