- Inflammation and Cancer Development in Pancreatic and Biliary Tract Cancer
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Lee SH, Park SW
- KMID: 2373366
- Korean J Gastroenterol.
- 2015 Dec;66(6):325-339.
- doi: 10.4166/kjg.2015.66.6.325
Chronic inflammation has been known to be a risk for many kinds of cancers, including pancreatic and biliary tract cancer. Recently, inflammatory process has emerged as a key mediator of... -
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- Effects of oncostatin M on hormone release of rat pituitary cells in primary culture
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Kim DS, Choi HS, Park YS, Kim TW
- KMID: 1128632
- J Korean Med Sci.
- 2000 Jun;15(3):323-326.
- doi: 10.3346/jkms.2000.15.3.323
It has become increasingly clear that cytokines play an important role in modulating neuroendocrine regulation, especially in the secretion of corticotropin (ACTH) in the pituitary. Oncostatin M (OSM), a cytokine... -
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- In vitro effects of meloxicam on the number, Foxp3 expression, production of selected cytokines, and apoptosis of bovine CD25+CD4+ and CD25-CD4+ cells
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Maslanka T, Jaroszewski JJ
- KMID: 1705513
- J Vet Sci.
- 2013 Jun;14(2):125-134.
- doi: 10.4142/jvs.2013.14.2.125
The purpose of this study was to evaluate the effect of meloxicam (MEL) on selected immune parameters of bovine CD25highCD4+, CD25lowCD4+, and CD25-CD4+ cells. Peripheral blood mononuclear cells (PBMCs) collected... -
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- IL-10 Mediates Rosiglitazone-Induced Kidney Protection in Cisplatin Nephrotoxicity
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Kim MG, Yang HN, Kim HW, Jo SK, Cho WY, Kim HK
- KMID: 1792925
- J Korean Med Sci.
- 2010 Apr;25(4):557-563.
- doi: 10.3346/jkms.2010.25.4.557
Cisplatin, a major anti-neoplastic drug, is known to be nephrotoxic and inflammation-inducing. A peroxisome proliferator-activated receptor gamma agonist, regulating lipid metabolism, has known to have anti-inflammatory effect, but the protection... -
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- Epigenetic Regulation of Cytokine Gene Expression in T Lymphocytes
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Lee CG, Sahoo A, Im SH
- KMID: 1758557
- Yonsei Med J.
- 2009 Jun;50(3):322-330.
- doi: 10.3349/ymj.2009.50.3.322
The developmental program of T helper and regulatory T cell lineage commitment is governed by both genetic and epigenetic mechanisms. The principal events, signaling pathways and the lineage determining factors... -
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- Cytokine Expression of Microscopic Colitis Including Interleukin-17
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Park E, Park YS, Park DR, Jung SA, Han DS, Jang BI, Kim YH, Kim WH, Jo YJ, Lee KH, Lee WM, Kim EK, Koo HS
- KMID: 2155646
- Gut Liver.
- 2015 May;9(3):381-387.
- doi: 10.5009/gnl13439
BACKGROUND/AIMS: Microscopic colitis is characterized by chronic watery diarrhea with specific pathological changes that can be diagnosed by microscopic examination. We performed immunohistochemical analysis of proinflammatory cytokines to investigate the... -
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- New-onset Diabetes as an Early Sign of Pancreatic Cancer
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Ahn J, Lee JK
- KMID: 1775732
- Korean J Gastroenterol.
- 2013 Nov;62(5):263-266.
- doi: 10.4166/kjg.2013.62.5.263
While long-standing diabetes is a risk factor of pancreatic cancer, new-onset diabetes could be a consequence of underlying pancreatic malignancy. About 30% to 50% of pancreatic cancer patients have new-onset... -
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- Conjugation and deconjugation of ubiquitin regulating the destiny of proteins
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Baek KH
- KMID: 1088651
- Exp Mol Med.
- 2003 Feb;35(1):1-7.
The homeostasis for a number of cellular proteins is regulated by not only phosphorylation and dephosphorylation, but also ubiquitination and deubiquitination. A number of proteins involved in the degradation of... -
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- Expression of Toll-Like Receptors in Verruca and Molluscum Contagiosum
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Ku JK, Kwon HJ, Kim MY, Kang H, Song PI, Armstrong , Ansel JC, Kim HO, Park YM
- KMID: 1713466
- J Korean Med Sci.
- 2008 Apr;23(2):307-314.
- doi: 10.3346/jkms.2008.23.2.307
Recent studies indicate that several Toll-like receptors (TLRs) are implicated in recognizing viral structures and instigating immune responses against viral infections. The aim of this study is to examine the... -
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- Immune mechanisms of Theiler's virus-induced demyelination
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Kim BS, Palna JP
- KMID: 755038
- Exp Mol Med.
- 1999 Sep;31(3):115-121.
No abstract available. -
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- Plasma Level of IL-6 and Its Relationship to Procoagulant and Fibrinolytic Markers in Acute Ischemic Stroke
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Song JW, Song KS, Choi JR, Kim SY, Rhee JH
- KMID: 1110743
- Yonsei Med J.
- 2006 Apr;47(2):201-206.
- doi: 10.3349/ymj.2006.47.2.201
Procoagulant or impaired fibrinolytic states as well as inflammatory reactions mediated by cytokines are likely involved in the pathogenesis of acute ischemic stroke. We examined the potential relationship between interleukin... -
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- Receptor activator of NF-kappaB ligand enhances the activity of macrophages as antigen presenting cells
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Park H, Park OJ, Shin J, Choi Y
- KMID: 1116197
- Exp Mol Med.
- 2005 Dec;37(6):524-532.
Receptor activator of NFkappaB ligand (RANKL) is known as a key regulator of osteoclastogenesis. However, the fact that fibroblasts and periodontal ligament cells express RANKL in response to bacterial substances,... -
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- Mast Cells in Allergic Asthma and Beyond
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Reuter S, Stassen M, Taube C
- KMID: 1779624
- Yonsei Med J.
- 2010 Nov;51(6):797-807.
- doi: 10.3349/ymj.2010.51.6.797
Mast cells have been regarded for a long time as effector cells in IgE mediated type I reactions and in host defence against parasites. However, they are resident in all... -
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- Change of connexin 37 in allergen-induced airway inflammation
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Park SJ, Lee KS, Kim SR, Min KH, Lee KY, Choe YH, Park SY, Hong SH, Lee YC
- KMID: 1090966
- Exp Mol Med.
- 2007 Oct;39(5):629-640.
Gap junction channels formed with connexins directly link to the cytoplasm of adjacent cells and have been implicated in intercellular signaling. Connexin 37 (Cx37) is expressed in the gas-exchange region... -
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- Evaluation of Stem Cell Components in Retrocorneal Membranes
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Lee SH, Kim KW, Kim MK, Chun YS, Kim JC
- KMID: 1796949
- J Korean Med Sci.
- 2014 Jun;29(6):846-851.
- doi: 10.3346/jkms.2014.29.6.846
The purpose of this study was to elucidate the origin and cellular composition of retrocorneal membranes (RCMs) associated with chemical burns using immunohistochemical staining for primitive cell markers. Six cases... -
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- Angiopoietin-1 Modified Human Umbilical Cord Mesenchymal Stem Cell Therapy for Endotoxin-Induced Acute Lung Injury in Rats
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Huang ZW, Liu N, Li D, Zhang HY, Wang Y, Liu Y, Zhang LL, Ju XL
- KMID: 2374208
- Yonsei Med J.
- 2017 Jan;58(1):206-216.
- doi: 10.3349/ymj.2017.58.1.206
PURPOSE: Angiopoietin-1 (Ang1) is a critical factor for vascular stabilization and endothelial survival via inhibition of endothelial permeability and leukocyte- endothelium interactions. Hence, we hypothesized that treatment with umbilical cord... -
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- Clinical implications of advances in liver regeneration
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Kwon YJ, Lee KG, Choi D
- KMID: 2155285
- Clin Mol Hepatol.
- 2015 Mar;21(1):7-13.
- doi: 10.3350/cmh.2015.21.1.7
Remarkable advances have been made recently in the area of liver regeneration. Even though liver regeneration after liver resection has been widely researched, new clinical applications have provided a better... -
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- The dose of cyclophosphamide for treating paraquat-induced rat lung injury
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Choi JS, Jou SS, Oh MH, Kim YH, Park MJ, Gil HW, Song HY, Hong SY
- KMID: 1503779
- Korean J Intern Med.
- 2013 Jul;28(4):420-427.
- doi: 10.3904/kjim.2013.28.4.420
BACKGROUND/AIMS: Cyclophosphamide (CP) is a promising treatment for severe cases of paraquat (PQ) poisoning. We investigated the effective dose of CP for mitigating PQ-induced lung injury. METHODS: Adult male Sprague-Dawley rats... -
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- Increased Expression of Cathelicidin by Direct Activation of Protease-Activated Receptor 2: Possible Implications on the Pathogenesis of Rosacea
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Kim JY, Kim YJ, Lim BJ, Sohn HJ, Shin D, Oh SH
- KMID: 2070215
- Yonsei Med J.
- 2014 Nov;55(6):1648-1655.
- doi: 10.3349/ymj.2014.55.6.1648
PURPOSE: Recent findings of increased cathelicidin protein and its proteolytic fragments in rosacea suggest a pathogenic role for cathelicidin in this disease. The relationship between cathelicidin and protease-activated receptor 2... -
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- The Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein, a toll-like receptor 4 agonist, enhances dendritic cell-based cancer vaccine potency
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Noh KT, Shin SJ, Son KH, Jung ID, Kang HK, Lee SJ, Lee EK, Shin YK, You JC, Park YM
- KMID: 1383795
- Exp Mol Med.
- 2012 May;44(5):340-349.
In this study, we showed the direct interaction between Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein (FAP) and toll-like receptor4 (TLR4) via co-localization and binding by using confocal microscopy and... -
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