- Evaluating the therapeutic efficacy of NAD supplementation in management of metabolic dysfunction-associated steatotic liver disease: Key considerations
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Lu X, Yang R, Chen Y, Chen D
- KMID: 2557404
- Clin Mol Hepatol.
- 2024 Jul;30(3):582-584.
- doi: 10.3350/cmh.2023.0555
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- METTL3 Affects Spinal Cord Neuronal Apoptosis by Regulating Bcl-2 m6A Modifications After Spinal Cord Injury
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Guo S, Lin T, Chen G, Shangguan Z, Zhou L, Chen Z, Shi T, Chen D, Wang Z, Liu W
- KMID: 2543563
- Neurospine.
- 2023 Jun;20(2):623-636.
- doi: 10.14245/ns.2346170.085
Objective: Spinal cord injury (SCI) is a severe type of neurological trauma. N6-methyladenosine (m6A) modification is one of the most common internal modifications of RNA. The role of METTL3, the... -
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- The Role of Gut Microbiota and Genetic Susceptibility in the Pathogenesis of Pancreatitis
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Xu F, Yang C, Tang M, Wang M, Cheng Z, Chen D, Chen X, Liu K
- KMID: 2533177
- Gut Liver.
- 2022 Sep;16(5):686-696.
- doi: 10.5009/gnl210362
Pancreatitis is one of the most common inflammatory diseases of the pancreas caused by autodigestion induced by excessive premature protease activation. However, recognition of novel pathophysiological mechanisms remains a still... -
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- Asiatic Acid Protects Dopaminergic Neurons from Neuroinflammation by Suppressing Mitochondrial ROS Production
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Chen D, Zhang XY, Sun J, Cong QJ, Chen WX, Ahsan HM, Gao J, Qian JJ
- KMID: 2456218
- Biomol Ther.
- 2019 Sep;27(5):442-449.
- doi: 10.4062/biomolther.2018.188
This study sought to evaluate the effects of Asiatic acid in LPS-induced BV2 microglia cells and 1-methyl-4-phenyl-pyridine (MPPâº)-induced SH-SY5Y cells, to investigate the potential anti-inflammatory mechanisms of Asiatic acid in... -
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- Radiofrequency Ablation Combined with Transcatheter Arterial Chemoembolization Therapy Versus Surgical Resection for Hepatocellular Carcinoma within the Milan Criteria: A Meta-Analysis
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Wang WD, Zhang LH, Ni JY, Jiang XY, Chen D, Chen YT, Sun HL, Luo JH, Xu LF
- KMID: 2413691
- Korean J Radiol.
- 2018 Aug;19(4):613-622.
- doi: 10.3348/kjr.2018.19.4.613
OBJECTIVE: To meta-analytically compare combined transarterial chemoembolization (TACE) plus radiofrequency ablation (RFA) and surgical resection (SR) for the treatment of hepatocellular carcinoma (HCC) within the Milan criteria. MATERIALS AND METHODS: PubMed,... -
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- Wedelolactone Promotes the Chondrogenic Differentiation of Mesenchymal Stem Cells by Suppressing EZH2
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Qin W, Yang L, Chen X, Ye S, Liu A, Chen D, Hu K
- KMID: 2545232
- Int J Stem Cells.
- 2023 Aug;16(3):326-341.
- doi: 10.15283/ijsc22046
Background and Objectives: Osteoarthritis (OA) is a degenerative disease that leads to the progressive destruction of articular cartilage. Current clinical therapeutic strategies are moderately effective at relieving OA-associated pain but cannot... -
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- Impact of Cardiovascular Disease on Health Insurance Coverage and Healthcare Use under Economic Stress: The National Health and Nutrition Examination Survey, 2003–2012
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Li J, Lai H, Chen D, Chen S, Lai S
- KMID: 2452054
- Osong Public Health Res Perspect.
- 2019 Jun;10(3):123-136.
- doi: 10.24171/j.phrp.2019.10.3.03
OBJECTIVES: Cardiovascular disease (CVD) has a substantial financial impact on healthcare systems in the US. This study aimed to examine the impact of CVD on health insurance coverage and health... -
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- Human Pneumonia Caused by Bordetella hinzii: First Case in Asia and Literature Review
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Chen D, Wang H, Lu X, Cui Y, Ma X, Lou J, Zhou H
- KMID: 2512727
- Ann Lab Med.
- 2021 Jul;41(4):439-442.
- doi: 10.3343/alm.2021.41.4.439
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- Imaging Features of Soft-Tissue Calcifications and Related Diseases: A Systematic Approach
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Hwang ZA, Suh KJ, Chen D, Chan WP, Wu JS
- KMID: 2424854
- Korean J Radiol.
- 2018 Dec;19(6):1147-1160.
- doi: 10.3348/kjr.2018.19.6.1147
Soft-tissue calcification refers to a broad category of lesions. Calcifications are frequently identified by radiologists in daily practice. Using a simple algorithm based on the distribution pattern of the lesions... -
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- Pharmacokinetics/Pharmacodynamics models of veterinary antimicrobial agents
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Luo W, Chen D, Wu M, Li Z, Tao Y, Liu Q, Pan Y, Qu W, Yuan Z, Xie S
- KMID: 2464090
- J Vet Sci.
- 2019 Sep;20(5):e40.
- doi: 10.4142/jvs.2019.20.e40
Misuse and abuse of veterinary antimicrobial agents have led to an alarming increase in bacterial resistance, clinical treatment failure, and drug residues. To address these problems, consistent and appropriate dosage... -
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- Novel DNAH1 Mutation Loci Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Literature Review
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Zhuang BJ, Xu SY, Dong L, Zhang PH, Zhuang BL, Huang XP, Li GS, You YD, Chen D, Yu XJ, Chang DG
- KMID: 2537104
- World J Mens Health.
- 2022 Oct;40(4):551-560.
- doi: 10.5534/wjmh.210119
The protein encoded by dynein axonemal heavy chain 1 (DNAH1) is a part of dynein, which regulates the function of cilia and sperm flagella. The mutant of DNAH1 causes the... -
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- Streptozotocin Diabetes Attenuates the Effects of Nondepolarizing Neuromuscular Relaxants on Rat Muscles
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Huang L, Chen D, Li S
- KMID: 2285547
- Korean J Physiol Pharmacol.
- 2014 Dec;18(6):461-467.
- doi: 10.4196/kjpp.2014.18.6.461
The hypothesis of this study was that diabetes-induced desensitization of rat soleus (SOL) and extensor digitorum longus (EDL) to non-depolarizing muscle relaxants (NDMRs) depends on the stage of diabetes and... -
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- Inhibition of glutathione metabolism attenuates esophageal cancer progression
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Peng L, Linghu R, Chen D, Yang J, Kou X, Wang XZ, Hu Y, Jiang YZ, Yang J
- KMID: 2382709
- Exp Mol Med.
- 2017 Apr;49(4):e318.
- doi: 10.1038/emm.2017.15
Esophageal squamous cell carcinoma (ESCC) is a deadly malignancy with regard to mortality and prognosis, and the 5-year survival rate for all patients diagnosed with ESCC remains poor. A better... -
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- Excessive copper in feed not merely undermines animal health but affects food safety
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Ma Z, Li Y, Han Z, Liu Z, Wang H, Meng F, Liu S, Chen D, Liu M
- KMID: 2516201
- J Vet Sci.
- 2021 May;22(3):e31.
- doi: 10.4142/jvs.2021.22.e31
Background: Blackened intestines in slaughtered pigs have been commonly observed in China in recent years. However, no cause has been reported. Objectives: We attempted to determine whether the blackening of the... -
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- Chitosan Nerve Grafts Incorporated with SKP-SC-EVs Induce Peripheral Nerve Regeneration
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Zhou X, Yu M, Chen D, Deng C, Zhang Q, Gu X, Ding F
- KMID: 2541495
- Tissue Eng Regen Med.
- 2023 Apr;20(2):309-322.
- doi: 10.1007/s13770-022-00517-6
BACKGROUND: Repair of long-distance peripheral nerve defects remains an important clinical problem. Nerve grafts incorporated with extracellular vesicles (EVs) from various cell types have been developed to bridge peripheral nerve... -
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- Transcriptome Sequencing Reveals the Potential Mechanisms of Modified Electroconvulsive Therapy in Schizophrenia
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Peng W, Tan Q, Yu M, Wang P, Wang T, Yuan J, Liu D, Chen D, Huang C, Tan Y, Liu K, Xiang B, Liang X
- KMID: 2516011
- Psychiatry Investig.
- 2021 May;18(5):385-391.
- doi: 10.30773/pi.2020.0410
Objective Schizophrenia (SCZ) is one of the most common and severe mental disorders. Modified electroconvulsive therapy (MECT) is the most effective therapy for all kinds of SCZ, and the underlying... -
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- A Novel Polyclonal Antiserum against Toxoplasma gondii Sodium Hydrogen Exchanger 1
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Xiao B, Kuang Z, Zhan Y, Chen D, Gao Y, Li M, Luo S, Hao W
- KMID: 2374013
- Korean J Parasitol.
- 2016 Feb;54(1):21-29.
- doi: 10.3347/kjp.2016.54.1.21
The sodium hydrogen exchanger 1 (NHE1), which functions in maintaining the ratio of Na+ and H+ ions, is widely distributed in cell plasma membranes. It plays a prominent role in... -
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- Ameliorative effects of atractylodin on intestinal inflammation and co-occurring dysmotility in both constipation and diarrhea prominent rats
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Yu C, Xiong Y, Chen D, Li Y, Xu B, Lin Y, Tang Z, Jiang C, Wang L
- KMID: 2371062
- Korean J Physiol Pharmacol.
- 2017 Jan;21(1):1-9.
- doi: 10.4196/kjpp.2017.21.1.1
Intestinal disorders often co-occur with inflammation and dysmotility. However, drugs which simultaneously improve intestinal inflammation and co-occurring dysmotility are rarely reported. Atractylodin, a widely used herbal medicine, is used to... -
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- Development and Evaluation of a Duplex Real-Time PCR Assay With a Novel Internal Standard for Precise Quantification of Plasma DNA
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Chen D, Pan S, Xie E, Gao L, Xu H, Xia W, Xu T, Huang P
- KMID: 2373609
- Ann Lab Med.
- 2017 Jan;37(1):18-27.
- doi: 10.3343/alm.2017.37.1.18
BACKGROUND: Circulating levels of cell-free DNA increase in many pathologic conditions. However, notable discrepancies in the quantitative analysis of cell-free DNA from a large number of laboratories have become a... -
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- Neuropathic Pain Components in Patients with Lumbar Spinal Stenosis
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Park SY, An HS, Moon SH, Lee HM, Suh SW, Chen D, Jeon JH
- KMID: 2366347
- Yonsei Med J.
- 2015 Jul;56(4):1044-1050.
- doi: 10.3349/ymj.2015.56.4.1044
PURPOSE: To determine the prevalence and characteristics of neuropathic pain (NP) in patients with lumbar spinal stenosis (LSS) according to subgroup analysis of symptoms. MATERIALS AND METHODS: We prospectively enrolled subjects... -
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