- Cell-free expression and functional reconstitution of CALM in clathrin assembly
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Kim JA, Kim HL
- KMID: 1085745
- Exp Mol Med.
- 2001 Jun;33(2):89-94.
Clathrin-mediated vesicle formation is an essential step in the intracellular trafficking of the protein and lipid. Binding of clathrin assembly protein to clathrin triskelia induces their assembly into clathrin-coated vesicles... -
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- Fucoxanthin Protects Cultured Human Keratinocytes against Oxidative Stress by Blocking Free Radicals and Inhibiting Apoptosis
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Zheng J, Piao MJ, Keum YS, Kim HS, Hyun JW
- KMID: 2170672
- Biomol Ther.
- 2013 Jul;21(4):270-276.
Fucoxanthin is an important carotenoid derived from edible brown seaweeds and is used in indigenous herbal medicines. The aim of the present study was to examine the cytoprotective effects of... -
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- Adenophora remotiflora protects human skin keratinocytes against UVB-induced photo-damage by regulating antioxidative activity and MMP-1 expression
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Kim HK
- KMID: 2390138
- Nutr Res Pract.
- 2016 Aug;10(4):371-376.
- doi: 10.4162/nrp.2016.10.4.371
BACKGROUND/OBJECTIVES: Chronic ultraviolet (UV) exposure-induced reactive oxygen species (ROS) are commonly involved in the pathogenesis of skin damage by activating the metalloproteinases (MMP) that break down type I collagen. Adenophora... -
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- The Effects of Quercetin on Paraquatinduced cell Damage
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Kim H, Lee SW
- KMID: 1944285
- J Korean Soc Emerg Med.
- 2007 Feb;18(1):41-48.
PURPOSE: Paraquat (1,1-dimethy-4,4-bipyridinium dichloride, PQ) is a very effective and widely used herbicide which was introduced commercially in 1962. However, its toxic effects are often fatal to humans and animals... -
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- Activation domain in P67phox regulates the steady state reduction of FAD in gp91phox
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Han CH, Lee MH
- KMID: 1103471
- J Vet Sci.
- 2000 Jun;1(1):27-31.
An activation domain in p67(phox) (residues 199-210) is critical for regulating NADPH oxidase activity in cell-free system [10] To determine the steady state reduction of FAD, thioacetamide-FAD was reconstituted in... -
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- Value of urinary topoisomerase-IIA cell-free DNA for diagnosis of bladder cancer
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Kim YH, Yan C, Lee IS, Piao XM, Byun YJ, Jeong P, Kim WT, Yun SJ, Kim WJ
- KMID: 2363132
- Investig Clin Urol.
- 2016 Mar;57(2):106-112.
- doi: 10.4111/icu.2016.57.2.106
PURPOSE: Topoisomerase-II alpha (TopoIIA ), a DNA gyrase isoform that plays an important role in the cell cycle, is present in normal tissues and various human cancers, and can show... -
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- Antioxidative Effects of Water-Soluble Chitinous Compounds on Oxidation of Low Density Lipoprotein in Macrophages
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Lee SH, Park SH, Lee YJ, Yoon Park , Choi YJ, Choi JS, Kang YH
- KMID: 2269697
- Korean J Nutr.
- 2003 Nov;36(9):908-917.
It has been proposed that oxidative modification of LDL (oxLDL) plays a significant role in the pathogenicity of atherogenesis. We tested the hypothesis that chitin and chitosan may function as... -
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- Neuroprotective mechanisms of dieckol against glutamate toxicity through reactive oxygen species scavenging and nuclear factor-like 2/heme oxygenase-1 pathway
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Cui Y, Amarsanaa , Lee JH, Rhim JK, Kwon JM, Kim SH, Park JM, Jung SC, Eun SY
- KMID: 2438086
- Korean J Physiol Pharmacol.
- 2019 Mar;23(2):121-130.
- doi: 10.4196/kjpp.2019.23.2.121
Glutamate toxicity-mediated mitochondrial dysfunction and neuronal cell death are involved in the pathogenesis of several neurodegenerative diseases as well as acute brain ischemia/stroke. In this study, we investigated the neuroprotective... -
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- The Polyphenol Chlorogenic Acid Attenuates UVB-mediated Oxidative Stress in Human HaCaT Keratinocytes
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Cha JW, Piao MJ, Kim KC, Yao CW, Zheng J, Kim SM, Hyun CL, Ahn YS, Hyun JW
- KMID: 2170653
- Biomol Ther.
- 2014 Mar;22(2):136-142.
We investigated the protective effects of chlorogenic acid (CGA), a polyphenol compound, on oxidative damage induced by UVB exposure on human HaCaT cells. In a cell-free system, CGA scavenged 1,1-diphenyl-2-picrylhydrazyl... -
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- Anti-Proliferative Activities of Vasicinone on Lung Carcinoma Cells Mediated via Activation of Both Mitochondria-Dependent and Independent Pathways
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Dey T, Dutta P, Manna P, Kalita J, Boruah HP, Buragohain AK, Unni B
- KMID: 2420392
- Biomol Ther.
- 2018 Jul;26(4):409-416.
- doi: 10.4062/biomolther.2017.097
Vasicinone, a quinazoline alkaloid from Adhatoda vasica Nees. is well known for its bronchodilator activity. However its antiproliferative activities is yet to be elucidated. Here-in we investigated the anti-proliferative effect... -
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- Neuroprotective Effect of Quercetin against Damage Induced by Oxygen Deprivation in Cultured Rat Cortical Neurons
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Kim H, Park JI, Lee SW, Park JS
- KMID: 2332594
- J Korean Soc Emerg Med.
- 2009 Apr;20(2):170-176.
PURPOSE: Neuronal hypoxia is clinically related to stroke, cardiac arrest, asphyxia, and various cases involving metabolic encephalopathy, which has led to much research looking for new neuroprotective strategies. Quercetin belongs... -
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- Scopoletin from Cirsium setidens Increases Melanin Synthesis via CREB Phosphorylation in B16F10 Cells
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Ahn MJ, Hur SJ, Kim EH, Lee SH, Shin JS, Kim MK, Uchizono J, Whang WK, Kim DS
- KMID: 2285524
- Korean J Physiol Pharmacol.
- 2014 Aug;18(4):307-311.
- doi: 10.4196/kjpp.2014.18.4.307
In this study, we isolated scopoletin from Cirsium setidens Nakai (Compositae) and tested its effects on melanogenesis. Scopoletin was not toxic to cells at concentrations less than 50 microM and... -
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- Dipeptides Inhibit Melanin Synthesis in Mel-Ab Cells through Down-Regulation of Tyrosinase
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Lee HE, Kim EH, Choi HR, Sohn UD, Yun HY, Baek KJ, Kwon NS, Park KC, Kim DS
- KMID: 2011164
- Korean J Physiol Pharmacol.
- 2012 Aug;16(4):287-291.
- doi: 10.4196/kjpp.2012.16.4.287
This study investigated the effects of proline-serine (PS) and valine-serine (VS) dipeptides on melanogenesis in Mel-Ab cells. Proline-serine and VS significantly inhibited melanin synthesis in a concentration-dependent manner, though neither... -
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- Superoxide Dismutase 1 Inhibits Alpha-Melanocyte Stimulating Hormone and Ultraviolet B-Induced Melanogenesis in Murine Skin
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Oh CT, Lee D, Koo K, Lee J, Yoon HS, Choi YM, Kwon TR, Kim BJ
- KMID: 2264861
- Ann Dermatol.
- 2014 Dec;26(6):681-687.
- doi: 10.5021/ad.2014.26.6.681
BACKGROUND: Over the last decade, the incidence of ultraviolet B (UVB)-related skin problems has increased. Oxidative stress caused by UVB induces the secretion of melanocyte growth and activating factors from... -
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- Modified Acellularization for Successful Vascular Xenotransplantation
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Jo WM, Sohn YS, Choi YH, Kim HJ, Cho HD
- KMID: 1713185
- J Korean Med Sci.
- 2007 Apr;22(2):262-269.
- doi: 10.3346/jkms.2007.22.2.262
The purpose of this study was to estimate the possibilities of an acellular matrix using a modified acellularization protocol, which circumvents immunological, microbiological, and physiological barriers. We treated porcine subclavian... -
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