- The Effects of Combination Therapy of Cathepsin K Inhibitor and PTH on Change of Bone Mineral Density in Animal Model of Osteoporosis
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Rhee Y
- KMID: 2169258
- Endocrinol Metab.
- 2011 Dec;26(4):295-296.
- doi: 10.3803/EnM.2011.26.4.295
No abstract available. -
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- Letter: The Effects of Combination Therapy of Cathepsin K Inhibitor and PTH on Change in Bone Mineral Density in an Animal Model of Osteoporosis
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Lee SA
- KMID: 2134828
- Endocrinol Metab.
- 2012 Mar;27(1):105-106.
- doi: 10.3803/EnM.2012.27.1.105
No abstract available. -
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- Response: The Effects of Combination Therapy of Cathepsin K Inhibitor and PTH on Change in Bone Mineral Density in an Animal Model of Osteoporosis
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Lee SH, Koh JM, Lee YS, Kim BJ, Choi JY, Kim GS
- KMID: 2134829
- Endocrinol Metab.
- 2012 Mar;27(1):107-107.
- doi: 10.3803/EnM.2012.27.1.107
No abstract available. -
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- New Antiresorptive Therapies for Postmenopausal Osteoporosis
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Choi HJ
- KMID: 2201015
- J Menopausal Med.
- 2015 Apr;21(1):1-11.
- doi: 10.6118/jmm.2015.21.1.1
Osteoporosis is a systemic skeletal disease whose risk increases with age and it is common among postmenopausal women. Currently, almost all pharmacological agents for osteoporosis target the bone resorption component... -
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- Increased Serum Cathepsin K in Patients with Coronary Artery Disease
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Li X, Li Y, Jin J, Jin D, Cui L, Li X, Rei Y, Jiang H, Zhao G, Yang G, Zhu E, Nan Y, Cheng X
- KMID: 2130814
- Yonsei Med J.
- 2014 Jul;55(4):912-919.
- doi: 10.3349/ymj.2014.55.4.912
PURPOSE: Cathepsin K is a potent collagenase implicated in human and animal atherosclerosis-based vascular remodeling. This study examined the hypothesis that serum CatK is associated with the prevalence of coronary... -
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- Pycnodysostosis with Multi-Segmental Spinal Canal Stenosis due to Ossification of the Yellow Ligament
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Wada K, Kanaya K, Murata Y, Kato Y
- KMID: 2270174
- Asian Spine J.
- 2015 Apr;9(2):286-289.
- doi: 10.4184/asj.2015.9.2.286
Pycnodysostosis is an autosomal recessive disorder characterized by osteosclerosis, small stature, acro-osteolysis of the distal phalanges, loss of the mandibular angle, separated cranial sutures with open fontanels, and frequent fractures.... -
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- Current and Upcoming Treatments for Osteoporosis
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Chung YS
- KMID: 2223113
- J Rheum Dis.
- 2012 Feb;19(1):4-10.
- doi: 10.4078/jrd.2012.19.1.4
Osteoporosis is a common senile disease that results in fragility fractures. With an ageing population, the medical and socioeconomic effect of osteoporosis, particularly postmenopausal osteoporosis, will increase further. Currently, good... -
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- Emerging Therapies for Osteoporosis
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McClung MR
- KMID: 2169649
- Endocrinol Metab.
- 2015 Dec;30(4):429-435.
- doi: 10.3803/EnM.2015.30.4.429
Although several effective therapies are available for the treatment of osteoporosis in postmenopausal women and older men, there remains a need for the development of even more effective and acceptable... -
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- TNF-α Inhibitor Reduces Odontoclast Formation in Diabetes Rats with Ligature-Induced Periodontitis
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Kim JH, Kim AR, Choi YH, Lee DE, Woo GH, Bak EJ, Yoo YJ
- KMID: 2394583
- Int J Oral Biol.
- 2017 Sep;42(3):137-142.
- doi: 10.11620/IJOB.2017.42.3.137
To determine the effect of the tumor necrosis factor-α (TNF-α) in odontoclast formation, we administrated a TNF-α inhibitor in rats with diabetes rats with periodontitis. The rats included in the... -
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- Immunohistochemical Observation of Plasma Cell Granuloma in Intraoral Chronic Inflammatory Lesions
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Kim YS, Lee SK
- KMID: 2136913
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2011 Jan;33(1):26-31.
PURPOSE: Chronic inflammatory gingival lesions occur as pyogenic granulomas or non-specific chronic suppurative lesions. METHODS: Of the 59 chronic inflammatory gingival lesions examined, plasma cell granuloma (n=14), which showed an intense... -
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- Different Protein Expressions between Peripheral Ameloblastoma and Oral Basal Cell Carcinoma Occurred at the Same Mandibular Molar Area
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Kim YS, Lee SK
- KMID: 1978948
- Korean J Pathol.
- 2014 Apr;48(2):151-158.
Peripheral ameloblastoma (PA) in gingiva is rare and often confused with oral basal cell carcinoma (OBCC). The tissues of one case of PA and one case of OBCC with the... -
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- Effects of the cathepsin K inhibitor with mineral trioxide aggregate cements on osteoclastic activity
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Kim HS, Kim S, Ko H, Song M, Kim M
- KMID: 2446665
- Restor Dent Endod.
- 2019 May;44(2):e17.
- doi: 10.5395/rde.2019.44.e17
OBJECTIVES: Root resorption is an unexpected complication after replantation procedures. Combining anti-osteoclastic medicaments with retrograde root filling materials may avert this resorptive activity. The purpose of this study was to... -
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- The Effects of Combination Therapy of Cathepsin K Inhibitor and PTH on Change in Bone Mineral Density in an Animal Model of Osteoporosis
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Lee SH, Koh JM, Lee YS, Kim BJ, Choi JY, Kim GS
- KMID: 2169260
- Endocrinol Metab.
- 2011 Dec;26(4):303-309.
- doi: 10.3803/EnM.2011.26.4.303
BACKGROUND: We hypothesized that combination therapy of cathepsin K inhibitor (CTKi) and human parathyroid hormone (1-34) (teriparatide, PTH) would overcome the coupling phenomenon of bone resorption and formation and thus... -
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- Peri-implant crevicular fluid levels of cathepsin-K, RANKL, and OPG around standard, short, and mini dental implants after prosthodontic loading
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Alan R, Marakoglu , Haliloglu
- KMID: 2212005
- J Periodontal Implant Sci.
- 2015 Oct;45(5):169-177.
- doi: 10.5051/jpis.2015.45.5.169
PURPOSE: Despite the high success rates of endosseous dental implants, their placement is restricted according to the height and volume of bone available. The use of short or mini dental... -
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- The Inhibitory Effects of Forsythia Koreana Extracts on the Metastatic Ability of Breast Cancer Cells and Bone Resorption by Osteoclasts
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Kim YL, Lee SK, Park KK, Chung WY
- KMID: 2353808
- J Cancer Prev.
- 2016 Jun;21(2):88-94.
- doi: 10.15430/JCP.2016.21.2.88
BACKGROUND: Breast cancer is the most common malignant disease in women. The patients with advanced breast cancer develop metastasis to bone. Bone metastasis and skeletal-related events by breast cancer are... -
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- Comparisons of orthodontic root resorption under heavy and jiggling reciprocating forces during experimental tooth movement in a rat model
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Hikida T, Yamaguchi , Shimizu M, Kikuta J, Yoshino T, Kasai K
- KMID: 2392203
- Korean J Orthod.
- 2016 Jul;46(4):228-241.
- doi: 10.4041/kjod.2016.46.4.228
OBJECTIVE: Root mobility due to reciprocating movement of the tooth (jiggling) may exacerbate orthodontic root resorption (ORR). "Jiggling" describes mesiodistal or buccolingual movement of the roots of the teeth during... -
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- Humanin suppresses receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation via AMP-activated protein kinase activation
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Kang N, Kim KW, Shin DM
- KMID: 2455817
- Korean J Physiol Pharmacol.
- 2019 Sep;23(5):411-417.
- doi: 10.4196/kjpp.2019.23.5.411
Humanin (HN) is a mitochondrial peptide that exhibits cytoprotective actions against various stresses and diseases. HN has been shown to induce the phosphorylation of AMP-activated protein kinase (AMPK), which is... -
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- The Molecular Mechanism of Baicalin on RANKL-induced Osteoclastogenesis in RAW264.7 Cells
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Ko SY
- KMID: 1431096
- Int J Oral Biol.
- 2013 Jun;38(2):67-72.
This study examined the anti-osteoclastogenic effects of baicalin on receptor activator of NF-kB ligand (RANKL)-induced RAW264.7 cells. Baicalin is a flavonoid that is produced by Scutellaria baicalensis and is known... -
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- Effect of remifentanil on pre-osteoclast cell differentiation in vitro
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Jeon HO, Choi IS, Yoon JY, Kim EJ, Yoon JU, Cho AR, Kim HJ, Kim CH
- KMID: 2405378
- J Dent Anesth Pain Med.
- 2018 Feb;18(1):9-17.
- doi: 10.17245/jdapm.2018.18.1.9
BACKGROUND: The structure and function of bone tissue is maintained through a constant remodeling process, which is maintained by the balance between osteoblasts and osteoclasts. The failure of bone remodeling... -
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- Effects of Liriopis Tuber Water Extract on RANKL-induced Osteoclast Differentiation
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Park KI, Oh J
- KMID: 1449618
- Korean J Phys Anthropol.
- 2011 Dec;24(4):237-244.
Increased formation and activation of osteoclast lead to unwanted bone resorption. Several natural products which have inhibitory effects on osteoclast differentiation and function are under investigation to prevent and treat... -
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