Endocrinol Metab.  2012 Mar;27(1):105-106. 10.3803/EnM.2012.27.1.105.

Letter: The Effects of Combination Therapy of Cathepsin K Inhibitor and PTH on Change in Bone Mineral Density in an Animal Model of Osteoporosis

Affiliations
  • 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Jeju National University Hospital, Jeju, Korea.

Abstract

No abstract available.


MeSH Terms

Animals
Bone Density
Cathepsin K
Cathepsins
Models, Animal
Osteoporosis
Cathepsin K
Cathepsins

Reference

1. Rachner TD, Khosla S, Hofbauer LC. Osteoporosis: now and the future. Lancet. 2011. 377:1276–1287.
2. Cusano NE, Bilezikian JP. Combination antiresorptive and osteoanabolic therapy for osteoporosis: we are not there yet. Curr Med Res Opin. 2011. 27:1705–1707.
3. Black DM, Greenspan SL, Ensrud KE, Palermo L, McGowan JA, Lang TF, Garnero P, Bouxsein ML, Bilezikian JP, Rosen CJ. PaTH Study Investigators. The effects of parathyroid hormone and alendronate alone or in combination in postmenopausal osteoporosis. N Engl J Med. 2003. 349:1207–1215.
4. Costa AG, Cusano NE, Silva BC, Cremers S, Bilezikian JP. Cathepsin K: its skeletal actions and role as a therapeutic target in osteoporosis. Nat Rev Rheumatol. 2011. 7:447–456.
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