- Effect of common bile duct ligation on liver cathepsins B, D, H and acid phosphatase activities in ethanol intoxicated rats
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Kim SS, Park ST, Kwak CS
- KMID: 1685600
- Korean J Gastroenterol.
- 1993 Aug;25(4):696-708.
No abstract available. -
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- Potential role(s) of cysteine cathepsins in cancer progression and metastasis
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Lee HR, Choi KC
- KMID: 2055088
- J Biomed Res.
- 2013 Mar;14(1):1-7.
Cancer is the result of damage to the genetic system, i.e., dysfunction of the DNA repair system, resulting in dysregulated expression of various molecules, leading to cancer formation, migration, and... -
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- Significance of the Expression of Cathepsins B, H, & L in Colonic Epithelial Neoplasms
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Sim JY, Lee MJ, Kee KH
- KMID: 1472618
- Korean J Pathol.
- 2009 Oct;43(5):408-412.
- doi: 10.4132/KoreanJPathol.2009.43.5.408
BACKGROUND: Cathepsin is associated with tumorigenesis, tumor invasion and metastasis through its ability to induce degradation of extracellular matrix components. METHODS: To investigate the correlation between cathepsin expression and tumor progression,... -
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- The Effects of Combination Therapy of Cathepsin K Inhibitor and PTH on Change of Bone Mineral Density in Animal Model of Osteoporosis
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Rhee Y
- KMID: 2169258
- Endocrinol Metab.
- 2011 Dec;26(4):295-296.
- doi: 10.3803/EnM.2011.26.4.295
No abstract available. -
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- Letter: The Effects of Combination Therapy of Cathepsin K Inhibitor and PTH on Change in Bone Mineral Density in an Animal Model of Osteoporosis
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Lee SA
- KMID: 2134828
- Endocrinol Metab.
- 2012 Mar;27(1):105-106.
- doi: 10.3803/EnM.2012.27.1.105
No abstract available. -
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- Cysteinyl Cathepsins: Multifunctional Enzymes in Cardiovascular Disease
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Li X, Liu Z, Cheng Z, Cheng X
- KMID: 2172207
- Chonnam Med J.
- 2012 Aug;48(2):77-85.
- doi: 10.4068/cmj.2012.48.2.77
Until recently, the role of lysosomal cysteine protease cathepsins in intracellular protein degradation was believed to be mainly restricted to scavenging. However, recent studies have revealed nontraditional roles for cysteine... -
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- Cathepsin D in Glial Tumors: Comparative Study with PCNA and Cell Cycle Analysis
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Chong YG, Han KS, Kim IS, Lee HK, Lee KC, Chu JW
- KMID: 2187823
- J Korean Neurosurg Soc.
- 1993 Feb;22(2):221-228.
No abstract available. -
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- Response: The Effects of Combination Therapy of Cathepsin K Inhibitor and PTH on Change in Bone Mineral Density in an Animal Model of Osteoporosis
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Lee SH, Koh JM, Lee YS, Kim BJ, Choi JY, Kim GS
- KMID: 2134829
- Endocrinol Metab.
- 2012 Mar;27(1):107-107.
- doi: 10.3803/EnM.2012.27.1.107
No abstract available. -
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- Resistance to Chemotherapy on Tumor Through Cathepsin B-dependent Activation of the NLRP3 Inflammasome
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Kwon EJ, Koh YS
- KMID: 2286278
- J Bacteriol Virol.
- 2013 Sep;43(3):233-234.
- doi: 10.4167/jbv.2013.43.3.233
Anticancer drugs kill tumor cells and increase host anti-tumor immunity. Interestingly, gemcitabin (Gem) and 5-fluorouracil (5-FU), widely used anticancer drugs, lead to IL-1beta secretion releasing cathepsin B which activates Nlrp3... -
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- Quantitative expression and localization of cysteine and aspartic proteases in human abdominal aortic aneurysms
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Lohoefer F, Reeps C, Lipp C, Rudelius M, Haertl F, Matevossian E, Zernecke A, Eckstein H, Pelisek J
- KMID: 2155360
- Exp Mol Med.
- 2014 May;46(5):e95.
- doi: 10.1038/emm.2014.20
Cysteine and aspartic proteases possess high elastolytic activity and might contribute to the degradation of the abdominal aortic aneurysm (AAA) wall. The aim of this study was to analyze, in... -
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- Immunocytochemical Assay of Cathepsin D in Fine Needle Aspiration Cytology of Breast Carcinoma and Benign Breast Diseases
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Park K, Ko I
- KMID: 2013349
- Korean J Cytopathol.
- 2000 Dec;11(2):75-81.
Cathepsin D is a protease which is known to facilitate invasion and metastasis of breast carcinoma. Overexpression of cathepsin D is associated with poor clinical outcome and biologic aggressiveness of... -
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- Immunohistochemical Expression of p53 and Cathepsin D in Prostatic Carcinoma
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Kim DJ, Kim EH, Yang SH, Kim CJ
- KMID: 2007099
- J Korean Cancer Assoc.
- 2000 Aug;32(4):810-816.
PURPOSE: To evaluate the prognostic significances of p53 and cathepsin D in the prostatic carcinoma, we compared them to other prognostic factors, such as nuclear grade and clinical stage. MATERIALS AND... -
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- The Difference of Cathepsin D Expression between Invasive Ductal Carcinoma and Ductal Carcinoma In Situ of the Breast
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Yoon HK, Jung SJ
- KMID: 2277696
- Korean J Pathol.
- 2004 Dec;38(6):408-414.
BACKGROUND: It is known that cathepsin D expression in host stromal cells is associated with a more aggressive tumor behavior in breast cancers. METHODS: Cathepsin D expression was examined in... -
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- Cathepsin D Expression in Intestinal Ganglion Cells of Neonate
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Kim DY, Lee SC, Park KW, Kim WK
- KMID: 2422188
- J Korean Assoc Pediatr Surg.
- 1999 Jun;5(1):39-44.
- doi: 10.13029/jkaps.1999.5.1.39
Diagnosing Hirschprung's disease is one of the clinical challenges of this disorder. In the stomach and the intestines, Cathepsin D was readily detected in cytoplasm of the rat gastric and... -
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- Role of Synovial Fibroblasts in Rheumatoid Arthritis
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Lee SH
- KMID: 2168060
- Hanyang Med Rev.
- 2005 May;25(2):36-42.
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial tissue proliferation with progressive joint destruction. The etiology of RA remains unknown, but many factors, including autoimmunity, cytokines and... -
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- Immunohistochemical Evaluation of Cathepsin D, MMP-2, and TIMP in Prostate Carcinoma
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Shim JW, Kim SR, Kim YJ, Ahn HK, Park YE, Kim SS, Kim MY
- KMID: 1921841
- Korean J Pathol.
- 1997 Apr;31(4):342-350.
Twenty six cases of primary adenocarcinoma of the prostate, ranging from 4 to 9 according to Gleason's summing score, were studied. Immunoreactivity was evaluated using the rabbit polyclonal anti-Cathepsin D... -
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- Relationship between Cathepsin D Expression and Other Prognostic Factors in Primary Breast Cancer
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Chung WJ, Park DE, Lee KM, Chae KM, Yoon KJ
- KMID: 2173601
- J Korean Breast Cancer Soc.
- 2001 Dec;4(2):172-178.
- doi: 10.4048/jkbcs.2001.4.2.172
PURPOSE: Cathepsin D, a lysosomal protease has been proposed to play a role in the local invasion and metastatic dissemination in primary breast cancer. Although there are many conflicting results,... -
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- Relationship between Cathepsin D Expression and Other Prognostic Factors in Primary Breast Cancer
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Chung WJ, Park DE, Lee KM, Chae KM, Yoon KJ
- KMID: 2324939
- J Korean Surg Soc.
- 2001 Apr;60(4):368-374.
PURPOSE: Cathepsin D, a lysosomal protease has been proposed to play a role in the local invasion and metastatic dissemination in primary breast cancer. Although there are many conflicting results,... -
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- Expression of Chromogranin A, Cathepsin D, Cyclin D1 and p53 proteins in Colorectal Adenocarcinoma
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Suh CH, Lee MJ, Cho SK
- KMID: 2141020
- Korean J Pathol.
- 2001 Feb;35(1):7-13.
BACKGROUND: The purpose of this study is to assess the roles of chromogranin A, cathepsin D, cyclin D1 and p53 protein expression in colorectal tumorigenesis. METHODS: 83 colorectal cancer and... -
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- C-reactive protein, a disintegrin and metalloproteinase 17 protein, and cathepsin D in chronic periodontitis with type 2 diabetes mellitus
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Moon KK, Kim HK, Kim YG, Suh JY, Lee JM
- KMID: 2465836
- Oral Biol Res.
- 2019 Sep;43(3):169-179.
- doi: 10.21851/obr.43.03.201909.169
The purpose of this study was to compare and quantify the expression of C-reactive protein (CRP), a disintegrin and metalloproteinase 17 (ADAM17) protein, and cathepsin D in the gingival tissues... -
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