- Oligometastasis: More Lessons to Be Learned
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Kim KH, Ahn YC, Oligometastasis Working Group, Korea Cancer Association
- KMID: 2537986
- Cancer Res Treat.
- 2023 Jan;55(1):1-4.
- doi: 10.4143/crt.2023.265
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- Top Ten Lessons Learned from Trials in Oligometastatic Cancers
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Tan VS, Palma DA
- KMID: 2537987
- Cancer Res Treat.
- 2023 Jan;55(1):5-14.
- doi: 10.4143/crt.2022.1460
Recent evidence supports the role of aggressive local treatment in the oligometastatic setting. In this review, we discuss the top 10 lessons we have learned from trials in oligometastatic cancers.... -
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- Adherence to Cancer Prevention Guidelines and Cancer Incidence and Mortality: A Population-Based Cohort Study
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Oh JK, Han M, Kim B, Park EY
- KMID: 2537988
- Cancer Res Treat.
- 2023 Jan;55(1):15-27.
- doi: 10.4143/crt.2021.1031
Purpose This study aimed to estimate the risk of cancer incidence and mortality according to adherence to lifestyle-related cancer prevention guidelines. Materials and Methods Men and women who participated in the... -
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- Establishing Patient-Derived Cancer Cell Cultures and Xenografts in Biliary Tract Cancer
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Kang J, Lee JY, Lee S, Kim D, Lim J, Jun HR, Jeon S, Kim YA, Park HS, Kim Kp, Chun SM, Lee HJ, Yoo C
- KMID: 2538006
- Cancer Res Treat.
- 2023 Jan;55(1):219-230.
- doi: 10.4143/crt.2021.1166
Purpose Biliary tract cancers (BTCs) are rare and show a dismal prognosis with limited treatment options. To improve our understanding of these heterogeneous tumors and develop effective therapeutic agents, suitable preclinical... -
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- Molecular and Immune Profiling of Syngeneic Mouse Models Predict Response to Immune Checkpoint Inhibitors in Gastric Cancer
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Lee D, Choi J, Oh HJ, Ham IH, Lee SH, Nomura S, Han SU, Hur H
- KMID: 2538002
- Cancer Res Treat.
- 2023 Jan;55(1):167-178.
- doi: 10.4143/crt.2022.094
Purpose Appropriate preclinical mouse models are needed to evaluate the response to immunotherapeutic agents. Immunocompetent mouse models have rarely been reported for gastric cancer. Thus, we investigated immunophenotypes and responses... -
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- Estimating Age-Specific Mean Sojourn Time of Breast Cancer and Sensitivity of Mammographic Screening by Breast Density among Korean Women
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Choi E, Suh M, Jung SY, Jung KW, Park S, Jun JK, Choi KS
- KMID: 2537999
- Cancer Res Treat.
- 2023 Jan;55(1):136-144.
- doi: 10.4143/crt.2021.962
Purpose High breast cancer incidence and dense breast prevalence among women in forties are specific to Asian. This study examined the natural history of breast cancer among Korean women. Materials and... -
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- Psychometric Validation of the Korean Version of the Cancer Survivors’ Unmet Needs (CaSUN) Scale among Korean Non–Small Cell Lung Cancer Survivors
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Kang D, Lee G, Kim S, Nam H, Kong S, Shim S, Lee JK, Jung W, Shin S, Kim HK, Zo JI, Shim YM, Shin DW, Cho J
- KMID: 2537992
- Cancer Res Treat.
- 2023 Jan;55(1):61-72.
- doi: 10.4143/crt.2021.1583
Purpose The purpose of the study was to validate the Korean version of Cancer Survivors’ Unmet Needs (CaSUN) scale among non–small cell lung cancer survivors. Materials and Methods Participants were recruited... -
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- Analysis of PIK3CA Mutation Concordance and Frequency in Primary and Different Distant Metastatic Sites in Breast Cancer
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Park J, Cho SY, Chang ES, Sung M, Song JY, Jung K, Kim SS, Shin YK, Choi YL
- KMID: 2538000
- Cancer Res Treat.
- 2023 Jan;55(1):145-154.
- doi: 10.4143/crt.2022.001
Purpose The purpose of this study was to investigate the concordance rate of PIK3CA mutations between primary and matched distant metastatic sites in patients with breast cancer and to verify... -
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- Analysis of Once-Daily Thoracic Radiotherapy Dose According to the Underlying Lung Disease in Patients with Limited-Stage Small Cell Lung Cancer Undergoing Concurrent Chemoradiotherapy
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Kim BH, Chung JH, Son J, Kim S, Wu HG, Kim HJ
- KMID: 2537993
- Cancer Res Treat.
- 2023 Jan;55(1):73-82.
- doi: 10.4143/crt.2021.1202
Purpose In the treatment of concurrent chemoradiotherapy (CCRT) in limited-stage small cell lung cancer, the optimal once-daily radiotherapy (RT) dose/fractionation remain unclear although it is the most frequently used. Therefore,... -
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- Osimertinib Combined with Systemic Chemotherapy for EGFR Mutant, T790M-Negative, Non–Small Cell Lung Cancer Patients Who Develop Leptomeningeal Metastases with Extracranial Progression to Prior EGFR TKI
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Kim HR, Jo H, Kim H, Hong J, Park S, Jung HA, Lee SH, Ahn JS, Ahn MJ
- KMID: 2538017
- Cancer Res Treat.
- 2023 Jan;55(1):344-349.
- doi: 10.4143/crt.2021.1603
Leptomeningeal metastasis (LM) is a rare but fatal clinical condition with a short survival time. The incidence of LM from epidermal growth factor receptor mutant (EGFRm) non–small cell lung cancer... -
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- Changes in Gut Microbiome upon Orchiectomy and Testosterone Administration in AOM/DSS-Induced Colon Cancer Mouse Model
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Song CH, Kim N, Nam RH, Choi SI, Jang JY, Lee HN
- KMID: 2538005
- Cancer Res Treat.
- 2023 Jan;55(1):196-218.
- doi: 10.4143/crt.2022.080
Purpose Sex hormones are known to affect the gut microbiota. Previously, we reported that endogenous and exogenous testosterone are associated with colorectal cancer (CRC) development and submucosal invasion. In the... -
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- Long-term Survivorship and Non-cancer Competing Mortality in Head and Neck Cancer: A Nationwide Population-Based Study in South Korea
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Jung YS, Lee D, Jung KW, Cho H
- KMID: 2537991
- Cancer Res Treat.
- 2023 Jan;55(1):50-60.
- doi: 10.4143/crt.2021.1086
Purpose As the survival of head and neck cancer (HNC) improves, survivors increasingly confront non-cancer–related deaths. This nationwide population-based study aimed to investigate non-cancer–related deaths in HNC survivors. Materials and Methods... -
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- The Efficacy of Alternate Systemic Intravenous Chemotherapy and Intra-arterial Chemotherapy Approach for Eye Globe Salvage in Retinoblastoma
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Han JW, Lee CS, Hahn SM, Ahn WK, Kim HS, Yun H, Lee SC, Kim BM, Kim DJ, Lyu CJ
- KMID: 2538010
- Cancer Res Treat.
- 2023 Jan;55(1):270-278.
- doi: 10.4143/crt.2021.1537
Purpose The advances in the treatment of retinoblastoma have enabled salvaging the globe in advanced stages with intra-arterial chemotherapy (IAC). We developed a strategy of alternate application of systemic intravenous... -
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- PD-L1 Upregulation by the mTOR Pathway in VEGFR-TKI–Resistant Metastatic Clear Cell Renal Cell Carcinoma
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Jeong SU, Hwang HS, Park JM, Yoon SY, Shin SJ, Go H, Lee JL, Jeong G, Cho YM
- KMID: 2538007
- Cancer Res Treat.
- 2023 Jan;55(1):231-244.
- doi: 10.4143/crt.2021.1526
Purpose Tyrosine kinase inhibitors (TKI) targeting vascular endothelial growth factor receptor (VEGFR) signaling pathways have been used for metastatic clear cell renal cell carcinoma (mCCRCC), but resistance to the drug... -
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- Phase 1 Study of No-Carrier Added 177Lu-DOTATATE (SNU-KB-01) in Patients with Somatostatin Receptor–Positive Neuroendocrine Tumors: The First Clinical Trial of Peptide Receptor Radionuclide Therapy in Korea
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Ryoo HG, Suh M, Kang KW, Lee DW, Han SW, Cheon GJ
- KMID: 2538016
- Cancer Res Treat.
- 2023 Jan;55(1):334-343.
- doi: 10.4143/crt.2021.1022
Purpose To provide a wider choice of treatment opportunities for patients with neuroendocrine tumor (NET) in Korea, we have conducted a phase 1, open-label, single-arm, dose-escalation study of SNU-KB-01, a... -
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- Effect of BRCA1/2 Mutational Status on Survival Outcomes According to Secondary Cytoreductive Surgery and Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer: A Real-World Evidence Study
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Kim SI, Lim H, Kim HS, Chung HH, Kim JW, Park NH, Song YS, Lee M
- KMID: 2538008
- Cancer Res Treat.
- 2023 Jan;55(1):245-257.
- doi: 10.4143/crt.2022.232
Purpose This study aimed to investigate the impact of BRCA1/2 mutational status on survival outcomes in patients with platinum-sensitive relapsed (PSR) epithelial ovarian cancer (EOC). Materials and Methods We retrospectively identified... -
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- Genomic Signatures from Clinical Tumor Sequencing in Patients with Breast Cancer Having Germline BRCA1/2 Mutation
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Kim JW, Kang HE, Choi J, Yun SG, Jung SP, Bae SY, You JY, Choi YJ, Kim YH, Park KH
- KMID: 2538001
- Cancer Res Treat.
- 2023 Jan;55(1):155-166.
- doi: 10.4143/crt.2021.1567
Purpose BRCA1 and BRCA2 are among the most important genes involved in DNA repair via homologous recombination (HR). Germline BRCA1/2 (gBRCA1/2)-related cancers have specific characteristics and treatment options but conducting gBRCA1/2... -
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- Image-Guided Versus Conventional Brachytherapy for Locally Advanced Cervical Cancer: Experience of Single Institution with the Same Practitioner and Time Period
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Lee TH, Kim KS, Kim HJ, Choi CH, Kang S, Eom KY, Wee CW, Song YS, Park NH, Kim JW, Chung HH, Kim HS, Lee M, Kang HC
- KMID: 2538009
- Cancer Res Treat.
- 2023 Jan;55(1):258-269.
- doi: 10.4143/crt.2022.418
Purpose This study aimed to compare treatment outcomes and toxicity profile between imaged-guided brachytherapy (IGBT) versus conventional brachytherapy (CBT) performed by the same practitioner during the same time period. Materials and... -
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- Universal Screening for Lynch Syndrome Compared with Pedigree-Based Screening: 10-Year Experience in a Tertiary Hospital
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Kim MH, Kim DW, Lee HS, Bang SK, Seo SH, Park KU, Oh HK, Kang SB
- KMID: 2538003
- Cancer Res Treat.
- 2023 Jan;55(1):179-188.
- doi: 10.4143/crt.2021.1512
Purpose Universal screening for Lynch syndrome (LS) refers to routine tumor testing for microsatellite instability (MSI) among all patients with colorectal cancer (CRC). Despite its widespread adoption, real-world data on... -
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- Interlaboratory Comparison Study (Ring Test) of Next-Generation Sequencing–Based NTRK Fusion Detection in South Korea
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Lee SE, Lee MS, Jeon YK, Shim HS, Kang J, Kim J, Choi YL
- KMID: 2537989
- Cancer Res Treat.
- 2023 Jan;55(1):28-40.
- doi: 10.4143/crt.2021.1572
Purpose Tropomyosin receptor kinase (TRK) inhibitors are approved for the treatment of neurotrophic receptor tyrosine kinase (NTRK) fusion-positive tumors. The detection of NTRK fusion using a validated method is required... -
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