- Peptidoglycan Induces the Production of Interleukin-8 via Calcium Signaling in Human Gingival Epithelium
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Son A, Shin DM, Hong JH
- KMID: 2071819
- Korean J Physiol Pharmacol.
- 2015 Jan;19(1):51-57.
- doi: 10.4196/kjpp.2015.19.1.51
The etiology of periodontal disease is multifactorial. Exogenous stimuli such as bacterial pathogens can interact with toll-like receptors to activate intracellular calcium signaling in gingival epithelium and other tissues. The... -
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- Increased store-operated Ca²⺠entry mediated by GNB5 and STIM1
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Kang N, Kang JY, Park S, Shin DM
- KMID: 2410098
- Korean J Physiol Pharmacol.
- 2018 May;22(3):343-348.
- doi: 10.4196/kjpp.2018.22.3.343
Recent human genetic studies have shown that Gβ5 is related to various clinical symptoms, such as sinus bradycardia, cognitive disability, and attention deficit hyperactivity disorder. Although the calcium signaling cascade... -
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- TRPC-Mediated Current Is Not Involved in Endocannabinoid-Induced Short-Term Depression in Cerebellum
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Chang W, Park JM, Kim J, Kim SJ
- KMID: 2071760
- Korean J Physiol Pharmacol.
- 2012 Apr;16(2):139-144.
- doi: 10.4196/kjpp.2012.16.2.139
It has been reported that activation of metabotropic glutamate receptor 1 (mGluR1) can mediate endocannabinoid-induced short-term depression of synaptic transmission in cerebellar parallel fiber (PF)-Purkinje cell (PC) synapse. mGluR1 has... -
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- The functional organisation of calcium signalling in exocrine acinar cells
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Petersen O
- KMID: 1026948
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S44-S45.
- doi: 10.3346/jkms.2000.15.S.S44
No abstract available. -
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- Autocrine Extracellular Signal-regulated Kinase Activation in Normal Human Keratinocytes is not Interrupted by Calcium Triggering and is Involved in the Control of Cell Cycle at the Early Stage of Calciuminduced Differentiation
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Park GT, Kim HY, Kim EK, Yang JM
- KMID: 1713190
- J Korean Med Sci.
- 2007 Apr;22(2):290-297.
- doi: 10.3346/jkms.2007.22.2.290
Normal human epidermal keratinocytes (NHEK) respond to the autocrine activated extracellular signal-regulated kinase (ERK) signaling pathway, which contributes to the survival of keratinocytes. However, during the condition of calcium-induced differentiation,... -
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- Calcium Signaling of Lysophosphatidylethanolamine through LPA1 in Human SH-SY5Y Neuroblastoma Cells
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Lee JM, Park SJ, Im DS
- KMID: 2375040
- Biomol Ther.
- 2017 Mar;25(2):194-201.
- doi: 10.4062/biomolther.2016.046
Lysophosphatidylethanolamine (LPE), a lyso-type metabolite of phosphatidylethanolamine, has been reported to be an intercellular signaling molecule. LPE mobilizes intracellular Ca²⺠through G-protein-coupled receptor (GPCR) in some cells types. However, GPCRs... -
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- Calcium Signaling in Salivary Secretion
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Kim JM, Lee SW, Park K
- KMID: 2405561
- J Korean Dent Sci.
- 2017 Dec;10(2):45-52.
- doi: 10.5856/JKDS.2017.10.2.45
Calcium has versatile roles in diverse physiological functions. Among these functions, intracellular Ca²⺠plays a key role during the secretion of salivary glands. In this review, we introduce the diverse... -
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- Xylitol stimulates saliva secretion via muscarinic receptor signaling pathway
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Park E, Na HS, Jeong S, Chung J
- KMID: 2452749
- Int J Oral Biol.
- 2019 Jun;44(2):62-70.
- doi: 10.11620/IJOB.2019.44.2.62
Xylitol is well-known to have an anti-caries effect by inhibiting the replication of cariogenic bacteria. In addition, xylitol enhances saliva secretion. However, the precise molecular mechanism of xylitol on saliva... -
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- Alteration of Expression of Ca(2+) Signaling Proteins and Adaptation of Ca(2+) Signaling in SERCA2(+/-) Mouse Parotid Acini
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Choi JH, Jo H, Hong JH, Lee SI, Shin DM
- KMID: 1084506
- Yonsei Med J.
- 2008 Apr;49(2):311-321.
- doi: 10.3349/ymj.2008.49.2.311
PURPOSE: The sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA), encoded by ATP2A2, is an essential component for G-protein coupled receptor (GPCR)-dependent Ca(2+) signaling. However, whether the changes in Ca(2+) signaling and Ca(2+) signaling... -
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- DA-6034 Induces [Ca2+]i Increase in Epithelial Cells
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Yang YM, Park S, Ji H, Kim TI, Kim EK, Kang KK, Shin DM
- KMID: 2285496
- Korean J Physiol Pharmacol.
- 2014 Apr;18(2):89-94.
- doi: 10.4196/kjpp.2014.18.2.89
DA-6034, a eupatilin derivative of flavonoid, has shown potent effects on the protection of gastric mucosa and induced the increases in fluid and glycoprotein secretion in human and rat corneal... -
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- Inhibition of Store-Operated Calcium Entry Protects Endothelial Progenitor Cells from Hâ‚‚Oâ‚‚-Induced Apoptosis
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Wang YW, Zhang JH, Yu Y, Yu J, Huang L
- KMID: 2351685
- Biomol Ther.
- 2016 Jul;24(4):371-379.
- doi: 10.4062/biomolther.2015.130
Store-operated calcium entry (SOCE), a major mode of extracellular calcium entry, plays roles in a variety of cell activities. Accumulating evidence indicates that the intracellular calcium ion concentration and calcium... -
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- Receptor-specific Ca2+ signaling in polarized cells
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Shin DM, Lee MG, Luo X, Muallem S
- KMID: 1026949
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S46-S48.
- doi: 10.3346/jkms.2000.15.S.S46
No abstract available. -
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- Modulation of InsP3 receptor properties by phosphorylation: targeting of PKA to InsP3 receptors shapes oscillatory calcium signals in pancreatic acinar cells
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Giovannucci DR, Sneyd J, Groblewski GE, Yule DI
- KMID: 1026953
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S55-S56.
- doi: 10.3346/jkms.2000.15.S.S55
No abstract available. -
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- The role of calmodulin in regulating calcium-permeable PKD2L1 channel activity
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Park EY, Baik JY, Kwak M, So I
- KMID: 2443609
- Korean J Physiol Pharmacol.
- 2019 May;23(3):219-227.
- doi: 10.4196/kjpp.2019.23.3.219
Polycystic kidney disease 2-like-1 (PKD2L1), polycystin-L or transient receptor potential polycystin 3 (TRPP3) is a TRP superfamily member. It is a calcium-permeable non-selective cation channel that regulates intracellular calcium concentration... -
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- Efffects of Fluoxetine on ATP-induced Calcium Signaling in PC12 Cells
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Lee YM, Kim HJ, Hong SH, Kim MJ, Min DS, Rhie DJ, Kim MS, Jo YH, Hahn SJ, Yoon SH
- KMID: 1517038
- Korean J Physiol Pharmacol.
- 2004 Feb;8(1):57-63.
Fluoxetine, a widely used anti-depressant compound, has several additional effects, including blockade of voltage-gated ion channels. We examined whether fluoxetine affects ATP-induced calcium signaling in PC12 cells by using fura-2-based... -
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- Involvement of the Ca2+ signaling pathway in osteoprotegerin inhibition of osteoclast differentiation and maturation
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Fu Y, Gu J, Wang Y, Yuan Y, Liu X, Bian J, Liu ZP
- KMID: 2164523
- J Vet Sci.
- 2015 Jun;16(2):151-156.
- doi: 10.4142/jvs.2015.16.2.151
The purpose of this study was to determine whether the Ca2+ signaling pathway is involved in the ability of osteoprotegerin (OPG) to inhibit osteoclast differentiation and maturation. RAW264.7 cells were... -
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- Effects of Apigenin on Glutamate-induced [Ca2+]i Increases in Cultured Rat Hippocampal Neurons
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Han JH, Kim KJ, Jang HJ, Jang JH, Kim MJ, Sung KW, Rhie DJ, Jo YH, Hahn SJ, Lee MY, Yoon SH
- KMID: 1486142
- Korean J Physiol Pharmacol.
- 2008 Apr;12(2):43-49.
- doi: 10.4196/kjpp.2008.12.2.43
Flavonoids have been shown to affect calcium signaling in neurons. However, there are no reports on the effect of apigenin on glutamate-induced calcium signaling in neurons. We investigated whether apigenin... -
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- Activation of calcium signaling by hepatitis B virus-X protein in liver cells
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Oh JC, Jeong DL, Kim IK, Oh SH
- KMID: 1109320
- Exp Mol Med.
- 2003 Aug;35(4):301-309.
Hepatitis B virus x gene product (HBx) is known to be a transactivator of transcriptional elements that regulate the expression of a variety of genes associated with the growth, differentiation,... -
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- Dust particles-induced intracellular Ca²⺠signaling and reactive oxygen species in lung fibroblast cell line MRC5
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Lee DU, Ji MJ, Kang JY, Kyung SY, Hong JH
- KMID: 2376961
- Korean J Physiol Pharmacol.
- 2017 May;21(3):327-334.
- doi: 10.4196/kjpp.2017.21.3.327
Epidemiologic interest in particulate matter (PM) is growing particularly because of its impact of respiratory health. It has been elucidated that PM evoked inflammatory signal in pulmonary epithelia. However, it... -
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- Phytosphingosine-1-phosphate stimulates chemotactic migration of L2071 mouse fibroblasts via pertussis toxin-sensitive G-proteins
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Kim MK, Park KS, Lee H, Kim YD, Yun J, Bae YS
- KMID: 1094659
- Exp Mol Med.
- 2007 Apr;39(2):185-194.
Phytosphingosine-1-phosphate (PhS1P) was found to stimulate an intracellular calcium increase via phospholipase C but not pertussis toxin (PTX)- sensitive G-proteins in L2071 mouse fibroblasts. PhS1P also activated ERK and p38... -
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