- Role for CD40 and CD40L Expression in Generating CD8 T Cell Response to Minor Histcompatibility Antigen, H60
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Jung KM, Choi EY
- KMID: 2150634
- Immune Netw.
- 2007 Dec;7(4):173-178.
- doi: 10.4110/in.2007.7.4.173
BACKGROUND: We studied the role for expression of CD40 and CD40L by CD4 and CD8 T cells in the generation of CD8 T cell response to minor histocompatibility antigen, H60.... -
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- Activation of B cells using Schneider 2 cells expressing CD40 ligand for the enhancement of antigen presentation in vitro
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Yoon SH, Cho HI, Kim TG
- KMID: 1116202
- Exp Mol Med.
- 2005 Dec;37(6):567-574.
CD40 ligand (CD40L) expressed by activated CD4+ T cells is a family member of membrane bound TNF family ligand and its interaction with CD40 expressed in APC has been shown... -
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- Studies on the Determining Factors at Each Stage of Germinal Center B Cell Differentiation
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Choe JS, Choi YS
- KMID: 1550787
- Korean J Immunol.
- 1999 Jun;21(2):159-164.
To delineate the individual role of follicular dendritic cells (FDC) and T cells at each stage of GC B cell differentiation at the clonal level and to analyze the signals... -
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- Enhancement of Proliferation and Antigen Presentation of Human B Cells in Vitro by K562 Cells Expressing CD40L
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Park JY, Yoon SH, Kim EK, Yun SO, Sohn HJ, Kim TG
- KMID: 2150630
- Immune Netw.
- 2007 Jun;7(2):80-86.
- doi: 10.4110/in.2007.7.2.80
BACKGROUND: CD40-activated B (CD40-B) cells might be an attractive source of autologous antigen-presenting cells (APCs) for immunotherapy due to the convenience to obtain from peripheral blood and expand in vitro.... -
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- Induction of IL-12 Experession in Bone Marrow-derived Mouse Dendritic Cells
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Youn JK, Kim HI, Kim AY, Park S, Lee MN
- KMID: 1550782
- Korean J Immunol.
- 1999 Jun;21(2):121-127.
Dendritic cells (DCs) are the most potent antigen presenting cells that can activate naive T cells. Mature DCs exress high levels of MHC and costimulatory molecules on their surface and... -
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- The relationship between serum adiponectin and inflammatory cytokines in obese Korean juveniles
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Byun SH, Kwon EB, Kim SY
- KMID: 2284643
- Korean J Pediatr.
- 2014 Dec;57(12):533-537.
- doi: 10.3345/kjp.2014.57.12.533
PURPOSE: Obesity is related to systemic inflammatory processes causing cardiovascular complications. Intercellular adhesion molecule-1 (ICAM-1), CD40 ligand (CD40L), P-selectin are newly described mediators of inflammation and have a significant effect... -
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- CD40-CD40 Ligand Interactions in the Production of IL-12 and IFN-gamma by Tuberculous Pleural Mononuclear Cells
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Song CH, Nam HH, An JO, Lee JS, Kim HJ, Park JK, Suhr JW, Jung SS, Na MJ, Paik TH, Jo EK
- KMID: 1571516
- Immune Netw.
- 2002 Sep;2(3):142-149.
- doi: 10.4110/in.2002.2.3.142
BACKGROUND: Our previous study showed that purified protein derivative (PPD)- stimulated pleural mononuclear cells (PMC) from tuberculous pleurisy (Tbp) produced significantly more IFN-gamma (10- to 70-fold) after in vitro PPD... -
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- Induction of Fas Antigen Expression, and Apotopsis of Human B Cell by CD40 and Tumor Necrosis Factor Receptor Ligation
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Chang DK, Yoo DH, Kim SY
- KMID: 1587011
- J Korean Rheum Assoc.
- 2001 Mar;8(1):20-33.
OBJECTIVE: CD40 and the TNFR belong to the NGF/TNFR supergene family. Ligation of CD40 on B cells induces activation ignals leading to proliferation, Ig isotype class switching, germinal center formation... -
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- Ligation of CD40 receptor in human B lymphocytes triggers the 5-lipoxygenase pathway to produce reactive oxygen species and activate p38 MAPK
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Ha YJ, Seul HJ, Lee JR
- KMID: 1097267
- Exp Mol Med.
- 2011 Feb;43(2):101-110.
- doi: 10.3858/emm.2011.43.2.012
Previously, we reported that CD40-induced production of reactive oxygen species (ROS) by NADPH oxidase requires the TNF receptor-associated factor (TRAF) 3, as well as the activities of phosphatidylinositol 3-kinase (PI3K)... -
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- Correlation between Intravoxel Incoherent Motion Magnetic Resonance Imaging Derived Metrics and Serum Soluble CD40 Ligand Level in an Embolic Canine Stroke Model
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Xu XQ, Wu CJ, Lu SS, Gao QQ, Zu QQ, Liu XL, Shi HB, Liu S
- KMID: 2427220
- Korean J Radiol.
- 2017 Oct;18(5):835-843.
- doi: 10.3348/kjr.2017.18.5.835
OBJECTIVE: To determine the relationship between intravoxel incoherent motion (IVIM) imaging derived quantitative metrics and serum soluble CD40 ligand (sCD40L) level in an embolic canine stroke model. MATERIALS AND METHODS: A... -
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- Expression of CCR2A, an isoform of MCP-1 receptor, is increased by MCP-1, CD40 ligand and TGF-beta in fibroblast like synoviocytes of patients with RA
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Cho ML, Yoon BY, Ju JH, Jung YO, Jhun JY, Park MK, Park SH, Cho CS, Kim HY
- KMID: 756073
- Exp Mol Med.
- 2007 Aug;39(4):499-507.
Cytokine and chemokine receptors play a key role in inflammation caused by rheumatoid arthritis (RA). Two isoforms of human CC chemokine receptor R2 (CCR2), the receptor of monocyte chemoattractant protein... -
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- Statin Reduced the Platelet CD63 and CD40L Expression in Atherosclerotic Ischemic Stroke with Hyperlipidemia
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Lee KM, Cho WS, Jeong MH, Lim YJ, Park KS, Cha JK
- KMID: 2137935
- J Korean Neurol Assoc.
- 2004 Oct;22(5):453-458.
BACKGROUND: Statin (HMG-coA-reductase inhibitor) has been known to protect vessels from atherothrombosis through various mechanisms. In this study, we evaluated the effects of statin on reducing the platelet expressions of... -
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- The Interaction Between Allelic Variants of CD86 and CD40LG: A Common Risk Factor of Allergic Asthma and Rheumatoid Arthritis
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Lee SH, Lee EB, Shin ES, Lee JE, Cho SH, Min KU, Park HW
- KMID: 2260258
- Allergy Asthma Immunol Res.
- 2014 Mar;6(2):137-141.
- doi: 10.4168/aair.2014.6.2.137
PURPOSE: Allergic asthma (AA) and rheumatoid arthritis (RA) are immune tolerance-related diseases, and immune tolerance is known to be influenced by costimulatory molecules. In this study, we sought to identify... -
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- Increase in Anti-Gal IgM Level is Associated With Early Graft Failure in Intraportal Porcine Islet Xenotransplantation
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Kang HJ, Lee H, Park EM, Kim JM, Shin JS, Kim JS, Park CG, Kim SJ
- KMID: 2363264
- Ann Lab Med.
- 2015 Nov;35(6):611-617.
- doi: 10.3343/alm.2015.35.6.611
BACKGROUND: Anti-Gal is a major antibody induced in non-human primates (NHPs) after xenotransplantation. To understand the mechanism of graft rejection, we investigated the association between anti-Gal responses and graft failure... -
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- The Effects of Statin and Niacin on Plaque Stability, Plaque Regression, Inflammation and Oxidative Stress in Patients With Mild to Moderate Coronary Artery Stenosis
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Lee K, Ahn TH, Kang WC, Han SH, Choi IS, Shin EK
- KMID: 2225071
- Korean Circ J.
- 2011 Nov;41(11):641-648.
- doi: 10.4070/kcj.2011.41.11.641
BACKGROUND AND OBJECTIVES: The aim of this study was to compare the effects of a combination of niacin and simvastatin to simvastatin alone, on plaque regression and inflammatory makers. SUBJECTS AND... -
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- X-linked Hyper-IgM Syndrome Associated with Cryptosporidium parvum and Cryptococcus neoformans Infections: the First Case with Molecular Diagnosis in Korea
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Jo EK, Kim HS, Lee MY, Iseki M, Lee JH, Song CH, Park JK, Hwang TJ, Kook H
- KMID: 2157605
- J Korean Med Sci.
- 2002 Feb;17(1):116-120.
- doi: 10.3346/jkms.2002.17.1.116
X-linked hyper-IgM syndrome (XHIM) is a rare primary immunodeficiency disorder, caused by mutations of the gene encoding CD40 ligand (CD40L; CD154). We report the clinical manifestations and mutational analysis of... -
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- Characterization of B Cells of Lymph Nodes and Peripheral Blood in a Patient with Hyper IgM Syndrome
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Kim DS, Shin KM, Yang WI, Shin JS, Song CH
- KMID: 2335702
- J Korean Pediatr Soc.
- 2003 Feb;46(2):128-136.
PURPOSE: Hyper IgM syndrome(HIGM) is characterized by severe recurrent bacterial infections with decreased serum levels of IgG, IgA, and IgE but elevated IgM levels. Recently, it has been classified into... -
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- Benzodiazepine-Associated Carcinogenesis: Focus on Lorazepam-Associated Cancer Biomarker Changes in Overweight Individuals
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Ku SC, Ho PS, Tseng YT, Yeh TC, Cheng SL, Liang CS
- KMID: 2424023
- Psychiatry Investig.
- 2018 Sep;15(9):900-906.
- doi: 10.30773/pi.2018.05.02.1
OBJECTIVE: Cellular, animal, and human epidemiological studies suggested that benzodiazepines increase the risk of cancer and cancer mortality. Obesity is also clearly linked to carcinogenesis. However, no human studies have... -
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- A Disintegrin and Metalloproteinase 8 as a Potential Blood Biomarker for Early Diagnosis of Gastric Cancer
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Chung HW, Kim JJ, Choi JI, Lee HR, Lim JB
- KMID: 2452951
- Yonsei Med J.
- 2019 Aug;60(8):713-719.
- doi: 10.3349/ymj.2019.60.8.713
PURPOSE: We aimed to evaluate the clinical significance of a disintegrin and metalloproteinase 8 (ADAM 8) as a potential blood biomarker for gastric cancer (GC). MATERIALS AND METHODS: Blood ADAM 8... -
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- The Effectiveness of IL-12 Administration and Fusion on Tumor Antigen Sensitization Methods for Dendritic Cells Derived from Patients with Myelogenous Leukemia
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Kim KW, Park SY, Hong YS
- KMID: 2054242
- Immune Netw.
- 2004 Mar;4(1):38-43.
- doi: 10.4110/in.2004.4.1.38
BACKGROUND: Immunotherapy using dendritic cells (DC) loaded with tumor antigens may represent a potentially effective method for inducing antitumor immunity. We evaluated the effectiveness of DC-based antitumor immune response in... -
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