- Overcome of acquired resistance to cisplatin by buthionine sulfoximine in human stomach and lung cancer cell lines
-
Hong WS, Kim CM, Lee CT, Kim YC, Lim YH, Lee JO, Kang TW, Hong SI
- KMID: 1694285
- J Korean Cancer Assoc.
- 1993 Feb;25(1):1-8.
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Enhanced Therapeutic Effects of Carboplatin by Buthionine Sulfoximine in MBT-2 Bladder Tumor
-
Min KJ, Ahn H, Kim HH, Lee ES, Lee CW
- KMID: 1914026
- Korean J Urol.
- 1994 Dec;35(12):1289-1302.
Glutathione based detoxification system in tumor cells was proposed as one of the drug resistance mechanisms and appeared to play as an obstacle in anticancer chemotherapy. It was evaluated that... -
- CITED
-
- Close
- SHARE
-
- Close
- Enhancement of Cytotoxicity of Chemotherapeutic Agents by Buthionine sulfoximine in Retinoblastoma Cell Line
-
Yang SW, Lee TW, Kim BH, Chang BL
- KMID: 2147771
- J Korean Ophthalmol Soc.
- 1996 Jan;37(1):86-102.
This study was performed to evaluate in vitro cytotoxicity of chemotherapeutic agents in established human retinoblastoma cell line, Y79 and to study the possibility of enhancing the cytotoxicity of chemotherapeutic... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Glutathione on Lead Induced Modulation of NO Synthesis in RAW 264.7 Cell
-
Shin SR, Oh GJ, Kwon KS, Yoon WH
- KMID: 2283317
- Korean J Prev Med.
- 2002 Nov;35(4):269-274.
OBJECTIVES: To evaluate the effect of glutathione(GSH) on lead induced modulation of nitric oxide(NO) synthesis, and to examine how lead modulates NO production in macrophages. METHODS: This study was observed in... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effects of Glutathione on Cyclosporine Induced Cytotoxicity in Cultured Insulinoma Cells
-
Kim BC, Kim SH, Min YD, Chang JH
- KMID: 2198971
- J Korean Soc Transplant.
- 2001 Dec;15(2):147-150.
PURPOSE: Cycloporine A (CsA) is a immunosuppressive agent most widely used in organ transplanted patients for preventing immunorejection, but it has some side effects, including hypertension, nephrotoxicity, hepatotoxicity and diabetes.... -
- CITED
-
- Close
- SHARE
-
- Close
- Interrelationship between Oxidative Neuronal Injury Induced by Iron or Buthionine Sulfoximine and NF-kappaB Activity in Mixed Cortical Cultures
-
Lee KS, Bae CS, Kim JK
- KMID: 2172401
- Chonnam Med J.
- 2001 Dec;37(4):377-382.
In order to delineate the interrelationship between oxidative neuronal injury and changes in NF-kappaB activity, the effects of trolox (a vitamin E analog antioxidant), cycloheximde (CHX, a protein synthesis inhibitor)... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Glutathione on Cisplatin-Induced Cytotoxicity In Human Cervical Cancer Cell Lines
-
Ahn TG, Han SJ
- KMID: 1925511
- Korean J Obstet Gynecol.
- 2002 Aug;45(8):1289-1293.
OBJECTIVE: The purpose of this study is to determine the effects of glutathione on cisplatin-induced cytotoxicity of human cervical carcinoma cell lines (SiHa: squamous cell carcinoma cell, CaSki: epidermoid metastatic... -
- CITED
-
- Close
- SHARE
-
- Close
- Mechanism of Hypoxia-Induced Cytotoxicity in Cultured Rat Retinal Neurons
-
Yoon YH, Lee J
- KMID: 2123632
- J Korean Ophthalmol Soc.
- 1997 Nov;38(11):1975-1986.
Retinal neurons are highly vulnerable to hypoxia/ischemia. Excitotoxicity and free radical injury have been proposed as the major mechanisms of ischemic retinal injury have been proposed as the major mechanisms... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Gutathione on Cyclosporine A-induced Cyotoxicity in Cultured Rat Insulinoma (RIN5mF) Cells
-
Choi DH, Lee BR, Jang DY, Kim JO, Kim BS, Chung KY, Lim TY, Shin BC, Bae HY
- KMID: 1569048
- J Korean Diabetes Assoc.
- 2002 Feb;26(1):57-63.
BACKGROUND: Cyclosporin A (CsA) is a immunosuppressive agent that is most widely used in organ transplanted patients to prevent immunorejection, However, it has some side effects, including diabetes mellitus, nephrotoxicity... -
- CITED
-
- Close
- SHARE
-
- Close
- Role of Glutathione and Protective Effect of Cysteamine in the Ammonia Induced Gastric Mucosal injury -Related with the Mechanism of Helicobacter pylori Associated Gastric Diseases ??
-
Roe IH, Lee MI, Hwang HC, Kim HY, Chin YJ, Lim CY, Song IH, Kim JW, Yang MR, Cho CH, Lee JH
- KMID: 2084878
- Korean J Gastroenterol.
- 1999 Jan;33(1):11-19.
BACKGROUND/AIMS: The mechanism of gastric mucosal injury by ammonia, one of the toxic products of Helicobacter pylori, is still unclear. We investigated the role and protective effect of glutathione in... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of neurotoxicity induced by some glutathione depletors in mouse cortical cell cultures
-
Lee GW, Lee KS, Park SH, Bae CS, Kim JK
- KMID: 1580804
- Korean J Physiol Pharmacol.
- 2000 Jun;4(3):177-183.
We examined the neurotoxic effects of 3 glutathione (GSH) depletors, buthionine sulfoximine (BSO), diethyl maleate (DEM) and phorone, under the presence of trolox, cycloheximide (CHX), pyrrolidine dithiocarbamate (PDTC) or MK-801 in primary mouse... -
- CITED
-
- Close
- SHARE
-
- Close
- GS28 Protects Neuronal Cell Death Induced by Hydrogen Peroxide under Glutathione-Depleted Condition
-
Lee HO, Byun YJ, Cho KO, Kim SY, Lee SB, Kim HS, Kwon OJ, Jeong SW
- KMID: 1448918
- Korean J Physiol Pharmacol.
- 2011 Jun;15(3):149-156.
- doi: 10.4196/kjpp.2011.15.3.149
Golgi SNAP receptor complex 1 (GS28) has been implicated in vesicular transport between intra-Golgi networks and between endoplasmic reticulum (ER) and Golgi. Additional role(s) of GS28 within cells have not... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Trolox, Cycloheximide or MK-801 on the Neuronal Cell Death Induced by FeCl2, Buthionine Sulfoximine or KCN in Primary Murine Mixed Cortical Cell Culture
-
Kim IH, Lee JG, Kim TS, Jung S, Kim JH, Kim SH, Kang SS, Lee JH, Lee KS, Kim JK
- KMID: 2118435
- J Korean Neurosurg Soc.
- 1997 Oct;26(10):1342-1350.
Oxidative stress is known to be a major neuropathologic mechanism in chronic neurodegenerative disorders as well as in stroke, trauma and epilepsy, and many kinds of oxidative insults induce neuronal... -
- CITED
-
- Close
- SHARE
-
- Close
- Neurotoxicity Screening in a Multipotent Neural Stem Cell Line Established from the Mouse Brain
-
Choi YS, Lee MC, Kim HS, Lee KH, Park YG, Kim HK, Jeong HS, Kim MK, Woo YJ, Kim SU, Ryu JK, Choi HB
- KMID: 1778041
- J Korean Med Sci.
- 2010 Mar;25(3):440-448.
- doi: 10.3346/jkms.2010.25.3.440
Neural stem cells (NSCs) have mainly been applied to neurodegeneration in some medically intractable neurologic diseases. In this study, we established a novel NSC line and investigated the cytotoxic responses... -
- CITED
-
- Close
- SHARE
-
- Close
