- Busulfan lung: report of 2 cases
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Lee SJ, Bae HM, Min YH, Hahn JS, Ko YW, Kim HK, Yang WI, Sung SH
- KMID: 1688267
- Korean J Hematol.
- 1992 Oct;27(2):351-360.
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- Transplantation of human umbilical cord blood CD34⺠cells into the liver of newborn NOD/SCID/IL-2Rγ null (NSG) mice after busulfan conditioning
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Ko Y, Jeong YH, Lee JA
- KMID: 2405070
- Blood Res.
- 2017 Dec;52(4):316-319.
- doi: 10.5045/br.2017.52.4.316
No abstract available. -
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- Application of stereological methods for unbiased estimation of sperm morphology in the mice induced by busulfan
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Panahi S, Abdollahifar MA, Aliaghaei , Nazarian H, Paktinat S, Abdi S, Farahani R
- KMID: 2399899
- Anat Cell Biol.
- 2017 Dec;50(4):301-305.
- doi: 10.5115/acb.2017.50.4.301
Busulfan is an anticancer drug, which causes the apoptosis germ cells and azoospermia in humans and animals. Abnormal morphology of spermatozoa related to the male infertility. The sperm morphology is... -
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- Effect of genistein administration on the recovery of spermatogenesis in the busulfan-treated rat testis
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Chi H, Chun K, Son H, Kim J, Kim G, Roh S
- KMID: 1493211
- Clin Exp Reprod Med.
- 2013 Jun;40(2):60-66.
- doi: 10.5653/cerm.2013.40.2.60
OBJECTIVE: Impairment of spermatogenesis has been identified as an inevitable side effect of cancer treatment. Although estrogen treatment stimulates spermatogenic recovery from the impaired spermatogenesis by suppressing the intra-testicular testosterone... -
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- A Case of Chronic Myelocytic Leukemia associated with Neurofibromatosis
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Choi BZ, Lee JH, Kim IH, Bae SK, Chung CY, Kim BS
- KMID: 2142508
- J Korean Pediatr Soc.
- 1980 Oct;23(10):849-854.
There have been few cases of Neurofibromatosis associated with Chronic Myelocytic Leukemia in literature and we found only one report in Korea which described the association of Chronic Myelocytic Leukemia... -
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- Dose-dependent effects of busulfan on dog testes in preparation for spermatogonial stem cell transplantation
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Hur TY, Lee SH, Ock SA, Song H, Park HJ, Lee R, Sung SH, Jhun H, Lee WY
- KMID: 2391101
- Lab Anim Res.
- 2017 Sep;33(3):264-269.
- doi: 10.5625/lar.2017.33.3.264
Successful male germ cell transplantation requires depletion of the host germ cells to allow efficient colonization of the donor spermatogonial stem cells. Although a sterilizing drug, busulfan, is commonly used... -
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- Targeted busulfan and fludarabine-based conditioning for bone marrow transplantation in chronic granulomatous disease
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Ju HY, Kang HJ, Hong CR, Lee JW, Kim H, Song SH, Yu KS, Jang IJ, Park JD, Park KD, Shin HY, Kim JG, Ahn HS
- KMID: 2362256
- Korean J Pediatr.
- 2016 Nov;59(Suppl 1):S57-S59.
- doi: 10.3345/kjp.2016.59.11.S57
Chronic granulomatous disease (CGD) is a primary immunodeficiency disease caused by impaired phagocytic function. Hematopoietic stem cell transplantation (HSCT) is a definitive cure for CGD; however, the use of HSCT... -
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- Quantification of Human Plasma-Busulfan Concentration by Liquid Chromatography-Tandem Mass Spectrometry
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Moon SY, Lim MK, Hong S, Jeon Y, Han M, Song SH, Lim KS, Yu KS, Jang IJ, Lee JW, Kang HJ, Song J
- KMID: 1781353
- Ann Lab Med.
- 2014 Jan;34(1):7-14.
- doi: 10.3343/alm.2014.34.1.7
BACKGROUND: Busulfan, an alkylating agent administered prior to hematopoietic stem cell transplantation, has a narrow therapeutic range and wide variability in metabolism. We developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS)... -
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- 3 Cases of Chronic Myelocytic Leukemia in Children
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Lim NK, Chung YC, Kim CK, Han KS, Kim BS
- KMID: 1969628
- Ewha Med J.
- 1978 Dec;1(4):293-297.
- doi: 10.12771/emj.1978.1.4.293
3 cases of chronic Myelocytic Leukemia in children were seen during 5 year period 1973~1978. They were 6 year old male, 10 year old male and 12 year old female.... -
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- Prospective validation of a novel dosing scheme for intravenous busulfan in adult patients undergoing hematopoietic stem cell transplantation
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Cho SH, Lee JH, Lim HS, Lee KH, Kim DY, Choe S, Bae KS, Lee JH
- KMID: 2285596
- Korean J Physiol Pharmacol.
- 2016 May;20(3):245-251.
- doi: 10.4196/kjpp.2016.20.3.245
The objective of this study was to externally validate a new dosing scheme for busulfan. Thirty-seven adult patients who received busulfan as conditioning therapy for hematopoietic stem cell transplantation (HCT)... -
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- Outcome of Hematopoietic Stem Cell Transplantation in Wiskott-Aldrich Syndrome
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Kim BK, Hong KT, Kang HJ, Choi JY, An HY, Shin HY
- KMID: 2435407
- Clin Pediatr Hematol Oncol.
- 2018 Oct;25(2):149-153.
- doi: 10.15264/cpho.2018.25.2.149
BACKGROUND: Wiskott-Aldrich syndrome (WAS) is a very rare disease and patients who do not receive timely treatment suffer from bleeding, infection, and malignancy. Hematopoietic stem cell transplantation (HSCT) has been... -
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- A Preliminary Report of Busulfan, Melphalan and Thiotepa or TBI-containing Bi-alkylator Chemotherapy as a Preparative Regimen for Allogeneic Bone Marrow Transplantation in Refractory or Relapsed Acute Leukemias
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Kim HJ, Min WS, Park SK, Kim DW, Lee JW, Han CH, Kim CC, Kim DJ
- KMID: 2059155
- J Korean Cancer Assoc.
- 1997 Oct;29(5):874-885.
PURPOSE: We assessed the three-alkylator combination of busulfan, melphalan and thiotepa or TBI, melphalan and thiotepa conditioning for allogeneic stem cell transplantation in 7 adult patients with refractory or relapsed... -
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- Advances in Treatment for Polycythemia Vera and Essential Thrombocythemia
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Kim SY
- KMID: 2268839
- Korean J Med.
- 2016 Apr;90(4):288-292.
- doi: 10.3904/kjm.2016.90.4.288
Although there have been substantial advances in confirming diagnoses and defining the molecular characteristics of polycythemia vera (PV) and essential thrombocythemia (ET), treatments for these conditions remain elementary. The main... -
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- The Effectiveness of Once-daily Intravenous Busulfan as a Conditioning Regime for Hematopoietic Stem Cell Transplantation in Children with Acute Myelogenous Leukemia
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Park SS, Kwak JW, Lim YT
- KMID: 2252166
- Korean J Hematol.
- 2009 Mar;44(1):1-7.
- doi: 10.5045/kjh.2009.44.1.1
BACKGROUND: There have recently been some reports suggesting that once-daily intravenous busulfan (IV Bu) as a conditioning regime for hematopoietic stem cell transplantation (HSCT) possibly reduces the toxicities without influencing... -
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- A Simple Dosing Scheme for Intravenous Busulfan Based on Retrospective Population Pharmacokinetic Analysis in Korean Patients
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Choe S, Kim G, Lim HS, Cho SH, Ghim JL, Jung JA, Kim UJ, Noh G, Bae KS, Lee D
- KMID: 2011162
- Korean J Physiol Pharmacol.
- 2012 Aug;16(4):273-280.
- doi: 10.4196/kjpp.2012.16.4.273
Busulfan is an antineoplastic agent with a narrow therapeutic window. A post-hoc population pharmacokinetic analysis of a prospective randomized trial for comparison of four-times daily versus once-daily intravenous busulfan was... -
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- Humanizing NOD/SCID/IL-2Rγnull (NSG) mice using busulfan and retro-orbital injection of umbilical cord blood-derived CD34+ cells
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Kang YK, Ko Y, Choi A, Choi HJ, Seo JH, Lee M, Lee JA
- KMID: 2172742
- Blood Res.
- 2016 Mar;51(1):31-36.
- doi: 10.5045/br.2016.51.1.31
BACKGROUND: Humanized mouse models are still under development, and various protocols exist to improve human cell engraftment and function. METHODS: Fourteen NOD/SCID/IL-2Rγnull (NSG) mice (4‒5 wk old) were conditioned with busulfan... -
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- Fludarabine-based myeloablative regimen as pretransplant conditioning therapy in adult acute leukemia/myelodysplastic syndrome: comparison with oral or intravenous busulfan with cyclophosphamide
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Lee JH, Choi J, Kwon KA, Lee S, Oh SY, Kwon HC, Kim HJ, Han JY, Kim SH
- KMID: 2083542
- Korean J Hematol.
- 2010 Jun;45(2):102-108.
- doi: 10.5045/kjh.2010.45.2.102
BACKGROUND: A combination of busulfan (Bu) and cyclophosphamide (Cy) has been used as a standard myeloablative regimen for allogeneic hematopoietic stem cell transplantation (HSCT). Recent studies postulate that fludarabine (Flu)... -
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- Safety and Pharmacokinetics of Intravenous Busulfan as Conditioning prior to Allogeneic Stem Cell Transplantation
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Park YH, Lee S, Kim YJ, Lee DG, Park CY, Shin HJ, Kim HJ, Min CK, Kim DW, Lee JW, Min WS, Kim CC
- KMID: 2083440
- Korean J Hematol.
- 2002 May;37(2):127-133.
BACKGROUND: The unpredictable intestinal absorption and bioavailability of oral busulfan (BU) has limited the drug's use in high-dose pretransplant conditioning therapy. To overcome these problems, several trials for the evaluation... -
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- Effects of Carthamus tinctorius on Semen Quality and Gonadal Hormone Levels in Partially Sterile Male Rats
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Bahmanpour S, Vojdani Z, Panjehshahin MR, Hoballah H, Kassas H
- KMID: 1856990
- Korean J Urol.
- 2012 Oct;53(10):705-710.
- doi: 10.4111/kju.2012.53.10.705
PURPOSE: Traditional herbal medicine is just one of the many different approaches using plants in the remedy of diseases. Carthamus tinctorius (CT) or safflower is a popular plant that is... -
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- Five Cases of Permanent Alopecia Following Chemotherapy
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Park JY, Choi YS, Lee WJ, Lee SJ, Na GY, Kim DW
- KMID: 2249367
- Korean J Dermatol.
- 2005 Oct;43(10):1365-1370.
With the development of chemotherapeutic agents and bone marrow transplantation, high dose conditioning chemotherapy before bone marrow transplantation, such as busulphan, have become more widely used. Of the side effects... -
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