Korean J Dermatol.  2005 Oct;43(10):1365-1370.

Five Cases of Permanent Alopecia Following Chemotherapy

Affiliations
  • 1Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea. seokjong@knu.ac.kr

Abstract

With the development of chemotherapeutic agents and bone marrow transplantation, high dose conditioning chemotherapy before bone marrow transplantation, such as busulphan, have become more widely used. Of the side effects following chemotherapy, the cutaneous side effects of hair loss occur in high incidence. Alopecia following chemotherapy was generally known to recover completely in spite of subtle changes to the hair shaft. However, we recently experienced five cases of permanent incomplete regrowth of hair after cessation of conventional chemotherapy or high dose conditioning chemotherapy. In Korea, permenant alopecia following chemotherapy has not yet been reported and we reviewed them with the possible risk factors such as duration and kind of chemotherapeutic agents.

Keyword

Permanent alopecia; Chemotherapy; Busulphan

MeSH Terms

Alopecia*
Bone Marrow Transplantation
Busulfan
Drug Therapy*
Hair
Incidence
Korea
Risk Factors
Busulfan
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