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Trends in Developing Extracellular Vesicle-Based Therapeutics

Lee J

Extracellular vesicles are nano-sized vesicles surrounded by lipid bilayers, and all cells release them to the extracellular environment for communication. Extracellular vesicles consist of molecules with various biological activities and...
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Cerebrospinal Fluid Seeding Versus Inflammation in Setting of Ventriculoperitoneal Shunt as a Potential Cause for Distant Recurrence of Glioblastoma

Gersey ZC, Plute T, Jaman E, Zhang X, Mitha R, Zinn PO, Pearce TM, Amankulor NM

Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults with a median survival of approximately 15 months, despite treatment, with most patients experiencing recurrence within 9 months...
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Supraorbital Approaches for Anterior Skull Base and Parasellar Lesions: Insights From a Single-Center Experience

Lee HG, Cho SJ, Park HR, Seo D

Background Modern neurosurgery has undergone significant evolution to include minimally inva-sive procedures, with the supraorbital approach (SOA) being a prime example. In this study, we aim to explore the surgical...
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A Rare Case of Intracranial Growing Teratoma Syndrome in a Young Adult

Gwak YG, Yang SH, Yoo YJ, Kim HH, Lee Y, Kim YI

Intracranial growing teratoma syndrome (iGTS) is a rare phenomenon in patients with non-germinomatous germ cell tumor (NGGCT) after chemotherapy or radiotherapy. It manifests as paradoxical growth of teratomatous components, with...
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Early High-Grade Transformation of IDH-Mutant Central Nervous System WHO Grade 2 Astrocytoma: A Case Report

Woo B, Han N, Kim JH, Gwak HS

High-grade transformation of low-grade gliomas has long been a poor prognostic factor during therapy. In 2016, the World Health Organization (WHO) Classification of Tumors of the Central Nervous System (CNS)...
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Malignant Transformation of Meningioma With TERT Promoter Mutation: A Case Report

Hong Y, Han N, Gwak HS

High-grade meningiomas make up a relatively minor proportion of meningiomas, which are one of the most common types of primary intracranial tumors in adults. Though rare, a considerable portion of...
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Survival After Newly-Diagnosed High-Grade Glioma Surgery: What Can We Learn From the French National Healthcare Database?

Depond CC, Bauchet L, Elhairech D, Tuppin P, Jecko V, Weller J, Metellus P

Background This study aimed to assess the overall survival (OS) of patients after high-grade glio-ma (HGG) resection and to search for associated prognostic factors. Methods A random sample of ad hoc...
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