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Vinpocetine inhibits the proliferation and induces apoptosis in human colon cancer cells

Kim MK, Park HJ, Kim Y, Kim YI, Bae SK, Kim HJ, Bae MK

Vinpocetine induces anti-inflammatory effects in various inflammatory diseases via the inhibition of phosphodiesterase type-1-independent nuclear factor-κB signaling pathway and the release of inflammatory cytokines. In this study, we investigated the...
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Resveratrol inhibits cell growth via targeting the Bmi-1 pathway in YD-10B human oral squamous cell carcinoma cells

Park KE, Ok CY, Jang HO, Bae MK, Bae SK

Resveratrol has been reported to exert anticancer activity via modulation of multiple pathways and genes. In this study, we examined the effect of resveratrol on YD-10B human oral squamous cell...
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Porphyromonas gingivalis lipopolysaccharide stimulates vascular smooth muscle cell migration through signal transducer and activator of transcription 3-mediated matrix metalloproteinase-9 expression

Kim Y, Park JY, Park HJ, Kim MK, Kim YI, Bae SK, Kim HJ, Bae MK

Periodontal diseases have been associated with the development of cardiovascular diseases. Accumulating evidences have indicated that Porphyromonas gingivalis, a major periodontopathic pathogen, plays a critical role in the pathogenesis of...
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14-3-3ζ Overexpression is Associated with Poor Prognosis in Ovarian Cancer

Kim HJ, Sung SH, Kim CY, Bae MK, Cho MS, Kim YH, Kim SC, Ju W

PURPOSE: 14-3-3ζ regulates cell signaling, cell cycle progression, and apoptosis, and its overexpression is associated with disease recurrence and poor clinical outcomes in some solid tumors. However, its clinicopathological role...
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Melatonin Rescues Human Dental Pulp Cells from Premature Senescence Induced by Hâ‚‚Oâ‚‚

Park S, Bak KJ, Ok CY, Park HJ, Jang HO, Bae MK, Bae SK

Although anti-aging activities of melatonin, a hormone secreted by the pineal gland, have been reported in senescence-accelerated mouse models and several types of cells, its impact and mechanism on the...
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The Effect of 1-Propanol on the Rotational Mobility of n-(9-Anthroyloxy) stearic acid in Outer Monolayers of Neuronal and Model Membranes

Ahn TY, Jin SD, Yang HJ, Yoon CD, Kim MK, An TK, Bae YJ, Seo SJ, Kim GS, Bae MK, Bae SK, Jang HO

The aim of this study was to provide a basis for the molecular mechanism underlying the pharmacological action of ethanol. We studied the effects of 1-propanol on the location of...
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Effect of hypoxia on angiogenesis-related proteins in human dental pulp cells

Kim MK, Kim SJ, Kim Y, Park HJ, Jo MJ, Bae SK, Kim HJ, Bae MK

Dental pulp is a highly vascularized tissue with high regenerative potential. Revascularization of severed vasculature in the tooth is required for pulp healing during avulsed tooth treatment. In this study,...
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Porphyromonas gingivalis Lipopolysaccharide Regulates Migration of Vascular Smooth Muscle Cells

Kim Y, Kim SJ, Kim MK, Park HJ, Kim HJ, Bae SK, Bae MK

Porphyromonas gingivalis, a foremost periodontal pathogen, has been known to cause periodontal diseases. Epidemiologic evidences have indicated the involvement of P. gingivalis in the development of cardiovascular diseases. In this...
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Effects of Alveolar Recruitment and Positive End-Expiratory Pressure on Oxygenation during One-Lung Ventilation in the Supine Position

Choi YS, Bae MK, Kim SH, Park JE, Kim SY, Oh YJ

PURPOSE: Hypoxemia during one-lung ventilation (OLV) remains a serious problem, particularly in the supine position. We investigated the effects of alveolar recruitment (AR) and positive end-expiratory pressure (PEEP) on oxygenation...
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Involvement of Heme Oxygenase-1 in Orexin-A-induced Angiogenesis in Vascular Endothelial Cells

Kim MK, Park HJ, Kim SR, Choi YK, Bae SK, Bae MK

The cytoprotective enzyme heme oxygenase-1 (HO-1) influences endothelial cell survival, proliferation, inflammatory response, and angiogenesis in response to various angiogenic stimuli. In this study, we investigate the involvement of HO-1...
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Single-Port Video-Assisted Thoracic Surgery for Secondary Spontaneous Pneumothorax: Preliminary Results

Kim MS, Yang HC, Bae MK, Cho S, Kim K, Jheon S

BACKGROUND: The aim of this study was to evaluate the feasibility of single-port video-assisted thoracic surgery (VATS) in the treatment of secondary spontaneous pneumothorax (SSP). METHODS: Twenty-four patients who were scheduled...
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Assessment of Potentially Inappropriate Medication Use in Korean Elderly Patients with Parkinson's Disease

Seo MK, Bae MK, Lee IH, Jeon S, Yoon JH

OBJECTIVES: The present study assessed the prevalence of the potentially inappropriate medication (PIM) use in Korean elderly patients with Parkinson's disease. In addition, this study examined risk factors that affect...
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A Neuromedin B Receptor Blockade Inhibits the Growth of Human Oral Cancer Cells

Park HJ, Jeon JH, Kim MK, Ryu MH, Kim YD, Bae SK, Bae MK

  • KMID: 1703485
  • Int J Oral Biol.
  • 2014 Mar;39(1):1-7.
Neuromedin B (NMB) acts as a growth factor or a morphogen and plays a role in cancer progression. Indeed, the NMB receptor (NMB-R) is overexpressed in different types of tumors....
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Autophagy Activity in Pulmonary Metastatic Tumor Tissues from Colorectal Cancer: A Pilot Study

Kim YS, Shin JH, Bae MK, Lee CY, Kim DJ, Chung KY, Lee JG

PURPOSE: Autophagy has been reported to be involved in treatment failure in tumor. We aimed to evaluate autophagy activity in tumor tissue and compare them between the recurrence and non-recurrence...
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Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells

Bae YH, Ryu JH, Park HJ, Kim KR, Wee HJ, Lee OH, Jang HO, Bae MK, Kim KW, Bae SK

Notch1 has been reported to be highly expressed in triple-negative and other subtypes of breast cancer. Mutant p53 (R280K) is overexpressed in MDA-MB-231 triple-negative human breast cancer cells. The present...
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Predictors of Recurrence after Thymoma Resection

Bae MK, Lee CY, Lee JG, Park IK, Kim DJ, Yang WI, Chung KY

PURPOSE: Recurrence rate is considered a better measure of clinical outcomes after thymoma resection than overall survival due to the indolent behavior of thymomas. This study was designed to determine...
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The Effect of Methanol on the Structural Parameters of Neuronal Membrane Lipid Bilayers

Joo HJ, Ahn SH, Lee HR, Jung SW, Choi CW, Kim MS, Bae MK, Chung IK, Bae SK, Jang HO, Yun I

The structures of the intact synaptosomal plasma membrane vesicles (SPMVs) isolated from bovine cerebral cortexs, and the outer and the inner monolayer separately, were evaluated with 1,6-diphenyl-1,3,5-hexatriene (DPH) and 1,3-di(1-pyrenyl)propane...
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AKAP12 regulates vascular integrity in zebrafish

Kwon HB, Choi YK, Lim JJ, Kwon SH, Her S, Kim HJ, Lim KJ, Ahn JC, Kim YM, Bae MK, Park JA, Jeong CH, Mochizuki , Kim KW

The integrity of blood vessels controls vascular permeability and extravasation of blood cells, across the endothelium. Thus, the impairment of endothelial integrity leads to hemorrhage, edema, and inflammatory infiltration. However,...
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Myxoinflammatory Fibroblastic Sarcoma in the Chest Wall

Narm KS, Park IK, Bae MK, Kim GJ

  • KMID: 2063132
  • Korean J Thorac Cardiovasc Surg.
  • 2012 Feb;45(1):65-68.
Myxoinflammatory fibroblastic sarcoma (MIFS) is a recently defined rare tumor. It is mainly found in the upper and lower extremities of adults. Due to its high local recurrence rate and...
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The Effect of Lidocaine.HCl on the Fluidity of Native and Model Membrane Lipid Bilayers

Park JS, Jung TS, Noh YH, Kim WS, Park WI, Kim YS, Chung IK, Sohn UD, Bae SK, Bae MK, Jang HO, Yun I

The purpose of this study is to investigated the mechanism of pharmacological action of local anesthetic and provide the basic information about the development of new effective local anesthetics. Fluorescent...
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