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Erratum: Human Platelet Antigen Datasets for Malays, Chinese, and Indians in Peninsular Malaysia

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Erratum: COVID-19 Molecular Testing in Korea: Practical Essentials and Answers From Experts Based on Experiences of Emergency Use Authorization Assays

Sung H, Roh KH, Hong KH, Seong MW, Ryoo N, Kim HS, Lee J, Kim SY, Ryu SW, Kim MN, Han MG, Lee SW, Lee H, Yoo CK, on behalf of COVID-19 Diagnosis Test Management Committee established by Korea Centers for Disease Control and Prevention

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A Novel Splice Variant (c.438T>A) of APC, Suspected by Family History and Confirmed by RNA Sequencing

Lee H, Kim HK, Yang DH, Hong YS, Lee W, Lim SB, Byeon JS, Chun S, Min WK

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A Case of Localized Fungal Pneumonia Caused by Rhodotorula mucilaginosa in an Immunocompetent Patient

Kim H, Byeon Sj, Kim CH, Bae YA, Lee H, Kim HS

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Application of Next Generation Sequencing in Laboratory Medicine

Zhong Y, Xu F, Wu J, Schubert J, Li MM

The rapid development of next-generation sequencing (NGS) technology, including advances in sequencing chemistry, sequencing technologies, bioinformatics, and data interpretation, has facilitated its wide clinical application in precision medicine. This review...
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A Sensitive and Specific Liquid ChromatographyTandem Mass Spectrometry Assay for Simultaneous Quantification of Salivary Melatonin and Cortisol: Development and Comparison With Immunoassays

Shin S, Oh H, Park HR, Joo EY, Lee SY

Melatonin and cortisol are clinically important for diagnosing sleep and mood disorders. We developed and validated a liquid chromatography-tandem mass spectrometry (LC-MS/ MS) assay for simultaneous measurement of salivary melatonin and...
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Effectiveness of Plasma and Urine Neutrophil Gelatinase-Associated Lipocalin for Predicting Acute Kidney Injury in High-Risk Patients

Yi A, Lee CH, Yun YM, Kim H, Moon HW, Hur M

Background: Neutrophil gelatinase-associated lipocalin (NGAL) is a useful biomarker for acute kidney injury (AKI) prediction. However, studies on whether using both plasma NGAL (PNGAL) and urine NGAL (UNGAL) can improve...
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Comparison of Three Blood Collection Tubes for 35 Biochemical Analytes: The Becton Dickinson Barricor Tube, Serum Separating Tube, and Plasma Separating Tube

Shin S, Oh J, Park HD

The Barricor tube (Becton Dickinson [BD], Sunnyvale, CA, USA) was recently developed to mechanically separate plasma by increasing the centrifugation rate. We compared the Barricor tube with existing serum- and...
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Commutability Assessment of Candidate External Quality Assessment Materials for Aminotransferase Activity Measurements Based on Different Approaches in China

Long Q, Qi T, Zhang T, Wang J, Zeng J, Yan Y, Wang M, Huang W, Zhao H, Chen W, Zhang C

Background: Using commutable external quality assessment (EQA) materials is important for monitoring successful harmonization efforts. We assessed the commutability of four human serum pool (HSP) preparations to identify candidate EQA...
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Moving Rate of Positive Patient Results as a Quality Control Tool for High-Sensitivity Cardiac Troponin T Assays

Li T, Cao S, Wang Y, Xiong Y, He Y, Ke P, Huang X

Background: A small shift in high-sensitivity cardiac troponin T (hs-cTnT) assays can lead to different result interpretation and consequent patient management. We explored whether a small bias could be detected...
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Platelet Inventory Management Program: Development and Practical Experience

Lee HJ, Oh SH, Jo SY, Kim IS

Background: Patients with ongoing or expected bleeding require platelet (PLT) transfusions; however, owing to the testing required after a blood donation, manufacturing PLT products may take 1.5–2.0 days after a...
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Antimicrobial Resistance Caused by KPC-2 Encoded by Promiscuous Plasmids of the Klebsiella pneumoniae ST307 Strain

Lee M, Choi TJ

Background: A lineage of Klebsiella pneumoniae that produces carbapenemase-2 (KPC-2), sequence type (ST) 307, emerged in 2017. We analyzed the complete sequences of plasmids from KPC-2-producing K. pneumoniae (KPC-Kp) ST307,...
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Clinical Utility of Mac-2 Binding Protein Glycosylation Isomer in Chronic Liver Diseases

Tamaki N, Kurosaki M, Loomba R, Izumi N

An accurate evaluation of liver fibrosis is clinically important in chronic liver diseases. Mac-2 binding protein glycosylation isomer (M2BPGi) is a novel serum marker for liver fibrosis. In this review,...
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Detection of Spinal Muscular Atrophy Using a Duplexed Real-Time PCR Approach With Locked Nucleic Acid-Modified Primers

Pan J, Zhang C, Teng Y, Zeng S, Chen S, Liang D, Li Z, Wu L

Background: Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder mainly caused by homozygous deletions that include exon 7 of the survival motor neuron 1 (SMN1) gene. A nearby...
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Evaluation of the CellaVision Advanced RBC Application for Detecting Red Blood Cell Morphological Abnormalities

Park SJ, Yoon J, Kwon JA, Yoon SY

Background: The Advanced RBC Application of the CellaVision DM9600 system (CellaVision AB, Lund, Sweden) automatically characterizes and classifies red blood cells (RBCs) into 21 morphological categories based on their size,...
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Reference Intervals for Thyroid-Associated Hormones and the Prevalence of Thyroid Diseases in the Chinese Population

Zou Y, Wang D, Cheng X, Ma C, Lin S, Hu Y, Yu S, Xia L, Li H, Yin Y, Liu H, Zhang D, Zhang K, Lian X, Xu T, Qiu L

Background: Thyroid diseases are highly prevalent worldwide, but their diagnosis remains a challenge. We established reference intervals (RIs) for thyroid-associated hormones and evaluated the prevalence of thyroid diseases in China. Methods:...
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Biomarker-Guided Risk Assessment for Acute Kidney Injury: Time for Clinical Implementation?

Albert C, Haase M, Albert A, Zapf A, Braun-Dullaeus RC, Haase-Fielitz A

Acute kidney injury (AKI) is a common and serious complication in hospitalized patients, which continues to pose a clinical challenge for treating physicians. The most recent Kidney Disease Improving Global...
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