- Effects of Prednisolone and Loteprednol Eyedrops on the Proliferation of Human Tenon's Capsule Fibroblasts
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Kang SH, Kim JW
- KMID: 2338451
- J Korean Ophthalmol Soc.
- 2013 Sep;54(9):1423-1428.
PURPOSE: To compare the effect of loteprednol etabonate (LE) with prednisolone acetate (PDA) drops on the proliferation of human Tenon's capsule fibroblasts (HTFBs). METHODS: Primarily cultured HTFBs were treated with serially... -
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- The role of inhaled and/or nasal corticosteroids on the bronchodilator response
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Lee JK, Suh DI, Koh YY
- KMID: 2280908
- Korean J Pediatr.
- 2010 Nov;53(11):951-956.
- doi: 10.3345/kjp.2010.53.11.951
BACKGROUND: To compare the profiles of the bronchodilator response (BDR) among children with asthma and/or allergic rhinitis (AR) and to determine whether BDR in these children is reduced by treatment... -
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- Improvement of Eosinophilic Otitis Media by Optimized Asthma Treatment
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Tanaka Y, Nonaka M, Yamamura Y, Tagaya E, Pawankar R, Yoshihara
- KMID: 2260338
- Allergy Asthma Immunol Res.
- 2013 May;5(3):175-178.
- doi: 10.4168/aair.2013.5.3.175
Eosinophilic otitis media (EOM) shows a very high rate of association with asthma, and intractable otitis media involves marked eosinophil infiltration into the middle ear. The middle ear space is... -
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- Limited Expression of Cytochrome P450 17alpha-Hydroxylase/17,20-Lyase in Prostate Cancer Cell Lines
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Jeong CW, Yoon CY, Jeong SJ, Hong SK, Byun SS, Lee SE
- KMID: 2315445
- Korean J Urol.
- 2011 Jul;52(7):494-497.
PURPOSE: Cytochrome P450 17alpha-hydroxylase/17,20-lyase (CYP17A1) is a key enzyme in the androgen biosynthesis pathway. CYP17A1 has been focused on because of the promising results of a potent CYP17A1 inhibitor in... -
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- Neuroprotective Effect of Rapamycin in Optic Nerve Transection Model
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Kim SH, Han YK, Park KH, Kim YJ
- KMID: 2215959
- J Korean Ophthalmol Soc.
- 2012 Aug;53(8):1150-1156.
- doi: 10.3341/jkos.2012.53.8.1150
PURPOSE: The present study investigated whether rapamycin activated autophagy in retinal ganglion cells (RGC) and evaluated its effect on RGC survival following optic nerve transection (ONT). METHODS: The activation of autophagy... -
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- Thrombin-induced Migration and Matrix Metalloproteinase-9 Expression Are Regulated by MAPK and PI3K Pathways in C6 Glioma Cells
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Kim J, Lee JW, Kim SI, Choi YJ, Lee WK, Jeong MJ, Cha SH, Lee HJ, Chun W, Kim SS
- KMID: 1448926
- Korean J Physiol Pharmacol.
- 2011 Aug;15(4):211-216.
- doi: 10.4196/kjpp.2011.15.4.211
Glioblastoma multiforme is one of the most common and aggressive tumors in central nervous system. It often possesses characteristic necrotic lesions with hemorrhages, which increase the chances of exposure to... -
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- Swiprosin-1 Regulates Cytokine Expression of Human Mast Cell Line HMC-1 through Actin Remodeling
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Ramesh TP, Kim YD, Kwon MS, Jun CD, Kim SW
- KMID: 2150656
- Immune Netw.
- 2009 Dec;9(6):274-284.
- doi: 10.4110/in.2009.9.6.274
BACKGROUND: Swiprosin-1 was identified in human CD8+ lymphocytes, mature B cells and non-lymphonoid tissue. We have recently reported that swiprosin-1 is expressed in mast cells and up-regulated in both in... -
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- The Efficacy of Inhaled Corticosteroid on Chronic Idiopathic Cough
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Han B, Jang SH, Kim YJ, Park S, Hwang YI, Kim DG, Kim CH, Hyun IG, Jung KS
- KMID: 2319279
- Tuberc Respir Dis.
- 2009 Nov;67(5):422-429.
BACKGROUND: The discomfort caused by chronic cough, that is persistent for more than 3 weeks, causes a number of patients to seek medical attention. However, the underlying disorder often remains... -
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- Effects of Smoking Cessation on Airflow Obstruction and Quality of Life in Asthmatic Smokers
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Jang AS, Park SW, Kim DJ, Uh S, Kim YH, Whang HG, Lim GI, Park CS
- KMID: 2260386
- Allergy Asthma Immunol Res.
- 2010 Oct;2(4):254-259.
- doi: 10.4168/aair.2010.2.4.254
PURPOSE: Smoking elicits airway inflammation and airflow obstruction in patients with asthma, even after smoking cessation. The aim of this study was to examine the effects of smoking cessation on... -
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- COX-2 inhibitor induced apoptosis in oral squamous cell carcinoma cell line through AKT pathway
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Seo YH, Han SJ, Lee JH
- KMID: 2184413
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2008 Jan;30(1):30-40.
The objectives of this study was to check up the effect of celecoxib, COX-2 inhibitor, on the pathogenesis of oral squamous cell carcinoma. After mefenamic acid, aspirin and celecoxib, COX-2... -
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- Economic Evaluations of Alternative Inhaled Steroid Medications in Patients with Asthma
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- KMID: 2234477
- Korean J Asthma Allergy Clin Immunol.
- 2008 Mar;28(1):26-34.
BACKGROUND: Asthma requires enormous social costs and deteriorates quality of life. Inhaled corticosteroids (ICSs) including budesonide (BUD), fluticasone propionate (FP), and ciclesonide (CIC) are currently considered the standard therapy for... -
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- The Efficacy of Immediate Diet for Reducing Local Adverse Events of Inhaled Corticosteroid: A Pilot Study
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Lee MK, Lee WY, Yong SJ, Shin KC, Kim CW, Lee JH, Jung S, Jung YR, Kim HS, Yu TS, Kim SH
- KMID: 2319898
- Tuberc Respir Dis.
- 2012 Aug;73(2):93-99.
BACKGROUND: Local adverse events associated with inhaled corticosteroid use, including dysphonia, pharyngitis and oral candidiasis, can affect adherence for treatment. 'Mouth rinsing method' has been used for reducing local adverse... -
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- Melatonin Induces Akt Phosphorylation through Melatonin Receptor- and PI3K-Dependent Pathways in Primary Astrocytes
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Kong PJ, Byun JS, Lim SY, Lee JJ, Hong SJ, Kwon KJ, Kim SS
- KMID: 1486141
- Korean J Physiol Pharmacol.
- 2008 Apr;12(2):37-41.
- doi: 10.4196/kjpp.2008.12.2.37
Melatonin has been reported to protect neurons from a variety of neurotoxicity. However, the underlying mechanism by which melatonin exerts its neuroprotective property has not yet been clearly understood. We... -
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- The Protective Effect of EGCG on INS-1 Cell in the Oxidative Stress and Mechanism
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Kim MK, Jung HS, Yoon CS, Kwon MJ, Koh KS, Rhee BD, Park JH
- KMID: 2222508
- Korean Diabetes J.
- 2008 Apr;32(2):121-130.
- doi: 10.4093/kdj.2008.32.2.121
BACKGROUND: Oxidative stress is important in both diabetic complications and the development and the progression of type 2 diabetes via the effects on the pancreatic beta-cells. EGCG (epigallocatechin galleate), a... -
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- Major clinical research advances in gynecologic cancer in 2011
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Suh DH, Kim K, Kim JW
- KMID: 2177515
- J Gynecol Oncol.
- 2012 Jan;23(1):53-64.
- doi: 10.3802/jgo.2012.23.1.53
The annual review of 2011 comprised 11 themes of major research achievements in gynecologic oncology including breast cancer. A potential paradigm shift in the management of ovarian cancer was reviewed... -
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- Comparison for the Effects of Triple Therapy with Salmeterol/Fluticasone Propionate and Tiotropium Bromide versus Individual Components in Patients of Severe COPD Combined with Bronchial Hyperresponsiveness
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Sohn JY, Kim SR, Park SJ, Lee HB, Lee YC, Rhee YK
- KMID: 2319294
- Tuberc Respir Dis.
- 2009 Dec;67(6):536-544.
BACKGROUND: A combination of salmeterol and fluticasone propionate (SFC) and tiotropium bromide (TIO) is commonly prescribed for COPD patients but there is little data on their effectiveness, particularly in COPD... -
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- An open, Multi center, Randomized, Parallel Group Study to Compare the Effectiveness and Safety of Fluticasone Plus Tulobuterol Versus Twice the Dose of Fluticasone Alone in Asthmatic Children
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Jeon YH, Yang HJ, Yoo Y, Kim YH, Jeong JT, Lee HR, Pyun BY
- KMID: 2314940
- Pediatr Allergy Respir Dis.
- 2009 Jun;19(2):125-136.
PURPOSE: We aim to compare the effectiveness and safety of fluticasone propionate (Flt) plus tulobuterol (Hk) versus high-dose Flt alone in controlling asthma in children. METHODS: Fifty three children aged 4... -
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- The Anti-apoptotic Effect of Adrenomedullin on Vascular Endothelial Cells in Radiocontrast Media-induced Apoptosis
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Kang KP, Lee AS, Jung YJ, Kim DH, Ko KS, Choi KH, Jeong YW, Lee S, Park SK, Sung MJ, Kim W
- KMID: 2253610
- Korean J Nephrol.
- 2008 Jan;27(1):4-12.
PURPOSE: Because vascular endothelial cells play a pivotal role in the vascular diseases, damage of vascular endothelial cells lead to progression of vascular disease. Apoptotic damage of cells is an... -
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- Induction of Melanogenesis by Rapamycin in Human MNT-1 Melanoma Cells
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Hah YS, Cho HY, Lim TY, Park DH, Kim HM, Yoon J, Kim JG, Kim CY, Yoon TJ
- KMID: 2434679
- Ann Dermatol.
- 2012 May;24(2):151-157.
BACKGROUND: Melanogenesis is one of the characteristic parameters of differentiation in melanocytes and melanoma cells. Specific inhibitors of phosphatidylinositol 3-kinase (PI3K), such as wortmannin and LY294002, stimulate melanin production in... -
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- Ginsenoside Rg2 Inhibits Lipopolysaccharide-Induced Adhesion Molecule Expression in Human Umbilical Vein Endothelial Cell
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Cho YS, Kim CH, Ha TS, Lee SJ, Ahn HY
- KMID: 1429384
- Korean J Physiol Pharmacol.
- 2013 Apr;17(2):133-137.
- doi: 10.4196/kjpp.2013.17.2.133
Vascular cell adhesion molecule 1 (VCAM-1), intercellular adhesion molecule 1 (ICAM-1), P- and E-selectin play a pivotal role for initiation of atherosclerosis. Ginsenoside, a class of steroid glycosides, is abundant... -
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