- A case of ruptured hepatic angiomyolipoma in a young male
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Kim SH, Kang TW, Lim K, Joh HS, Kang J, Sinn DH
- KMID: 2413122
- Clin Mol Hepatol.
- 2017 Jun;23(2):179-183.
- doi: 10.3350/cmh.2016.0027
A 31-year-old male visited a local hospital due to sudden-onset severe abdominal pain. Abdominal computed tomography revealed a solid cystic mass with a size of approximately 12 cm and exhibiting... -
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- Hepatic perivascular epithelioid cell tumor (PEComa): a case report with a review of literatures
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Son HJ, Kang DW, Kim JH, Han HY, Lee MK
- KMID: 2412118
- Clin Mol Hepatol.
- 2017 Mar;23(1):80-86.
- doi: 10.3350/cmh.2016.0034
Hepatic perivascular epithelioid cell tumors (PEComas) are very rare. We report a primary hepatic PEComa with a review of the literature. A 56-year-old women presented with a nodular mass detected... -
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- Elk-3 Contributes to the Progression of Liver Fibrosis by Regulating the Epithelial-Mesenchymal Transition
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Li TZ, Kim SM, Hur W, Choi JE, Kim JH, Hong SW, Lee EB, Lee JH, Yoon SK
- KMID: 2412161
- Gut Liver.
- 2017 Jan;11(1):102-111.
- doi: 10.5009/gnl15566
BACKGROUND/AIMS: The role of Elk-3 in the epithelial-mesenchymal transition (EMT) during liver fibrogenesis remains unclear. Here, we determined the expression of Elk-3 in in vitro and in vivo models and... -
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- Renoprotective Effects of a Highly Selective A3 Adenosine Receptor Antagonist in a Mouse Model of Adriamycin-induced Nephropathy
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Min HS, Cha JJ, Kim K, Kim JE, Ghee JY, Kim H, Lee JE, Han JY, Jeong LS, Cha DR, Kang YS
- KMID: 2468272
- J Korean Med Sci.
- 2016 Sep;31(9):1403-1412.
- doi: 10.3346/jkms.2016.31.9.1403
The concentration of adenosine in the normal kidney increases markedly during renal hypoxia, ischemia, and inflammation. A recent study reported that an A3 adenosine receptor (A3AR) antagonist attenuated the progression... -
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- Effect of intranasal rosiglitazone on airway inflammation and remodeling in a murine model of chronic asthma
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Lee HY, Rhee CK, Kang JY, Park CK, Lee SY, Kwon SS, Kim YK, Yoon HK
- KMID: 2373777
- Korean J Intern Med.
- 2016 Jan;31(1):89-97.
- doi: 10.3904/kjim.2016.31.1.89
BACKGROUND/AIMS: Asthma is characterized by airway hyperresponsiveness, inflammation, and remodeling. Peroxisome proliferator-activated receptors have been reported to regulate inflammatory responses in many cells. In this study, we examined the effects... -
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- Toward understanding the role of the neuron-specific BAF chromatin remodeling complex in memory formation
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Choi KY, Yoo M, Han JH
- KMID: 2070274
- Exp Mol Med.
- 2015 Apr;47(4):e155.
- doi: 10.1038/emm.2014.129
The long-term storage of memory requires the finely tuned coordination of intracellular signaling with the transcriptional, translational and epigenetic regulations of gene expression. Among the epigenetic mechanisms, however, we know... -
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- A Case of Liver Fibrosis with Splenomegaly after Oxaliplatin-Based Adjuvant Chemotherapy for Colon Cancer
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Kang GH, Moon HS, Lee ES, Kim SH, Sung JK, Lee BS, Jeong HY, Lee HY, Kang DY
- KMID: 1779429
- J Korean Med Sci.
- 2013 Dec;28(12):1835-1838.
- doi: 10.3346/jkms.2013.28.12.1835
Previous studies reported that oxaliplatin is associated with sinusoidal obstruction syndrome. However few reports on oxaliplatin induced liver fibrosis are found in the literature. Furthermore pathogenesis of liver fibrosis is... -
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- Clinical, Pathological, and Immunohistochemical Features of Adenomyoma in the Ampulla of Vater
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Choi YH, Kim MJ, Han JH, Yoon SM, Chae HB, Youn SJ, Kang MH, Sung R, Choi JW, Park SM
- KMID: 1711291
- Korean J Gastroenterol.
- 2013 Dec;62(6):352-358.
- doi: 10.4166/kjg.2013.62.6.352
BACKGROUND/AIMS: Ampullary adenomyoma is a benign lesion whose malignant potential has yet to be confirmed. Despite its benign nature, adenomyoma is frequently misdiagnosed as a carcinoma or adenoma and is... -
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- Staurosporine and cytochalasin D induce chondrogenesis by regulation of actin dynamics in different way
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Kim M, Song K, Jin EJ, Sonn J
- KMID: 1389731
- Exp Mol Med.
- 2012 Sep;44(9):521-528.
Actin cytoskeleton has been known to control and/or be associated with chondrogenesis. Staurosporine and cytochalasin D modulate actin cytoskeleton and affect chondrogenesis. However, the underlying mechanisms for actin dynamics regulation... -
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- The Role of Focal Adhesion Kinase in the TGF-beta-Induced Myofibroblast Transdifferentiation of Human Tenon's Fibroblasts
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Hong S, Lee JB, Iizuka Y, Song YK, Seong GJ, Han SH
- KMID: 1120181
- Korean J Ophthalmol.
- 2012 Feb;26(1):45-48.
- doi: 10.3341/kjo.2012.26.1.45
PURPOSE: To investigate the role of focal adhesion kinase (FAK) in transforming growth factor (TGF)-beta-induced myofibroblast transdifferentiation of human Tenon's fibroblasts. METHODS: Primary cultured human Tenon's fibroblasts were exposed to TGF-beta1... -
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- 5-Formylhonokiol exerts anti-angiogenesis activity via inactivating the ERK signaling pathway
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Zhu W, Fu A, Hu J, Wang T, Luo Y, Peng M, Ma Y, Wei Y, Chen L
- KMID: 1109403
- Exp Mol Med.
- 2011 Mar;43(3):146-152.
- doi: 10.3858/emm.2011.43.3.017
Our previous report has demonstrated that 5-formylhonokiol (FH), a derivative of honokiol (HK), exerts more potent anti-proliferative activities than honokiol in several tumor cell lines. In present study, we first... -
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- A Case of Primary Extragastrointestinal Stromal Tumor Presenting as Peritoneal Dissemination
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Yang HJ, Kim TH, Park MK, Lim CH, Lee KH, Kim CW, Han SW, Kim JA
- KMID: 1718374
- Korean J Gastroenterol.
- 2010 Nov;56(5):319-323.
- doi: 10.4166/kjg.2010.56.5.319
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract, but also occurs at a lower frequency in extra-gastrointestinal regions such as omentum, mesentery, retroperitoneum and... -
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- Inflammatory Myofibroblastic Tumor of the Kidney Misdiagnosed as Renal Cell Carcinoma
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Ryu KH, Im CM, Kim MK, Kwon D, Park K, Ryu SB, Choi C
- KMID: 1779272
- J Korean Med Sci.
- 2010 Feb;25(2):330-332.
- doi: 10.3346/jkms.2010.25.2.330
The inflammatory myofibroblastic tumor (IMT), also knowns as inflammatory pseuduotumor, is a soft tissue lesion of unknown etiology. In the urogenital tract, IMT mainly affects the urinary bladder or prostate,... -
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- Therapeutic Effect of Allogenic Bone Marrow Transplantation in Acute TNBS-induced Colitis
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Maeng LS, Chang ED, Chae HS, Kim JS, Min JY, Sohn HS, Rho SY, Kim HK, Cho YS, Choi KY, Lee HK
- KMID: 1792762
- Korean J Gastroenterol.
- 2009 Jul;54(1):20-27.
- doi: 10.4166/kjg.2009.54.1.20
BACKGROUND/AIMS: Bone marrow-derived cells (BMDC) contribute to tissue maintenance under many kinds of pathologic conditions. We carried out a study to see how BMDC play a role in the treatment... -
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- Perivascular Epithelioid Cell Tumor (PEComa) of Abdominal Cavity from Falciform Ligament: A Case Report
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Choi CW, Kim TO, Kim KY, Lee SM, Kim GH, Kang DH, Song GA, Kim S, Kim DH
- KMID: 1779144
- J Korean Med Sci.
- 2009 Apr;24(2):346-349.
- doi: 10.3346/jkms.2009.24.2.346
We present a case of perivascular epithelioid cell tumors (PEComas) in the abdominal cavity at the falciform ligament. A 30-yr-old Korean man visited to hospital for the evaluation of a... -
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- Transtorming Growth Factor beta1 Induces Epithelial-to-Mesenchymal Transition of A549 Cells
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Kim JH, Jang YS, Eom KS, Hwang YI, Kang HR, Jang SH, Kim CH, Park YB, Lee MG, Hyun IG, Jung KS, Kim DG
- KMID: 1713300
- J Korean Med Sci.
- 2007 Oct;22(5):898-904.
- doi: 10.3346/jkms.2007.22.5.898
Idiopathic pulmonary fibrosis (IPF) comprises an aggregate of mesenchymal cells. However, the cellular origin of these mesenchymal phenotypes remains unclear. Transforming growth factor beta1 (TGF-beta1) has been known as the... -
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- Inhibitory Effect of Angiotensin Blockade on Hepatic Fibrosis in Common Bile Duct-ligated Rats
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Park DH, Baik SK, Choi YH, Kim MY, Rhim DW, Kim JW, Kwon SO, Cho MY, Kim CH, Ahn SC
- KMID: 760706
- Korean J Hepatol.
- 2007 Mar;13(1):61-69.
BACKGROUNDS AND AIMS: Angiotensin receptors are found on hepatic stellate cells, which participate in hepatic fibrosis. Therefore, it is presumed that angiotensin has a role in hepatic fibrosis. The... -
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- Heterogeneous nuclear ribonuclear protein C is increased in the celecoxib-induced growth inhibition of human oral squamous cell carcinoma
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Lee EJ, Kim SH, Kwark YE, Kim J
- KMID: 1094145
- Exp Mol Med.
- 2006 Jun;38(3):203-209.
Celecoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) that is a critical factor in carcinogenesis, but precise mechanism of its action remains to be elucidated. Here we evaluated the inhibitory... -
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- Metaplastic Carcinoma with Extensive Chondroid Differentiation in the Breast (Chondroid Carcinoma)
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Kim YJ, Shim HS, Lee H, Jung WH
- KMID: 1110752
- Yonsei Med J.
- 2006 Apr;47(2):259-263.
- doi: 10.3349/ymj.2006.47.2.259
Metaplastic breast carcinoma is very rare, and metaplastic carcinoma with chondroid differentiation is even rarer. Here, we report a case of metaplastic carcinoma with extensive chondroid differentiation mimicking chondrosarcoma that... -
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- Gastrointestinal Stromal Tumors in Koreans: It's Incidence and the Clinical, Pathologic and Immunohistochemical Findings
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Kim KM, Kang DW, Moon WS, Park JB, Park CK, Sohn JH, Jeong JS, Cho MY, Jin SY, Choi JS, Kang DY, Gastrointestinal Stromal Tumor Committee, The Korean Gastrointestinal Pathology Study Group
- KMID: 2157748
- J Korean Med Sci.
- 2005 Dec;20(6):977-984.
- doi: 10.3346/jkms.2005.20.6.977
Seven hundred forty seven cases of gastrointestinal stromal tumors (GISTs) in Koreans who were diagnosed between 2001 and 2002 were analyzed to evaluate their occurrence and their clinical, pathologic and... -
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