J Korean Neurol Assoc.  2023 May;41(2):128-132. 10.17340/jkna.2023.2.4.

Intravascular Large B-cell Lymphoma Presenting as Rapidly Progressive Encephalopathy

Affiliations
  • 1Department of Neurology, Kosin University Gospel Hospital, Busan, Korea
  • 2Department of Nuclear Medicine, Kosin University Gospel Hospital, Busan, Korea

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is a rare form of non-Hodgkin’s lymphoma that selectively involves the lumina of vessels, and may present as ischemic stroke. A 62-year-old man presented with progressive aphasia, dementia, seizure and stroke-like symptom. Brain magnetic resonance imaging revealed dynamic progressive fluid attenuated inversion recovery lesions and multiple punctate microbleeds in the bilateral subcortical region. A kidney biopsy revealed IVLBCL. We report a patient with IVLBCL presenting as rapidly progressive encephalopathy.

Keyword

Lymphoma; Brain diseases; Magnetic resonance imaging
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