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Multidimensional Early Prediction Score for Drug-Resistant Epilepsy

Kang KW, Cho YW, Lee SK, Jung KY, Kim JH, Kim DW, Lee SA, Hong SB, Na IS, Lee SH, Baek WK, Choi SY, Kim MK

Background and Purpose Achieving favorable postoperative outcomes in patients with drug-resistant epilepsy (DRE) requires early referrals for preoperative examinations. The purpose of this study was to investigate the possibility of...
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Low-Density Lipoprotein Cholesterol Level, Statin Use and Myocardial Infarction Risk in Young Adults

Jeong H, Han K, Yoo SJ, Kim MK

Objective: The consequences of blood lipid abnormalities for cardiovascular disease risk in young adults is unclear. Optimal lipid levels may also vary depending on whether a statin drug is taken....
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Promising Blood Biomarkers for Clinical Use in Alzheimer’s Disease: A Focused Update

Park SA, Jang YJ, Kim MK, Lee SM, Moon SY

Alzheimer’s disease (AD) is the most-common cause of neurodegenerative dementia, and it is characterized by abnormal amyloid and tau accumulation, which indicates neurodegeneration. AD has mostly been diagnosed clinically. However,...
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Imaging Features and Pathological Correlation in Mixed Microcystic and Angiomatous Meningioma: A Case Report

Choi K, Kim DY, Kim HJ, Hwang G, Kim MK, Kim HG, Paik S

Meningiomas are the most common intracranial tumors. However, microcystic and angiomatous meningiomas are very rare subtypes that present unusual imaging findings. Hence, radiological diagnosis of these tumors can be challenging....
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Safety and efficacy of nilotinib in adult patients with chronic myeloid leukemia: a post-marketing surveillance study in Korea

Ahn SY, Son SK, Lee GH, Kim I, Cheong JW, Lee WS, Kim BS, Jo DY, Jung CW, Seong CM, Lee JH, Yuh YJ, Kim MK, Ryoo HM, Park MR, Cho SH, Kim HG, Zang DY, Park J, Kim H, Lee S, Kim SH, Chang MH, Lee HS, Choi CW, Kwon J, Lim SN, Oh SJ, Joo I, Kim DW

Background Nilotinib is a tyrosine kinase inhibitor approved by the Ministry of Food and Drug Safety for frontline and 2nd line treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). This...
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Development and Roll-Out of A Coronavirus Disease 2019 Clinical Pathway for Standardized Qualified Care in Public Hospitals in Korea

Kwak MY, Jo EY, Chin B, Park SE, Yim J, Lee JE, Jo KE, Kim YS, Lee JE, Yoon YK, Seo YB, Jeong SJ, Kang YM, Joo EJ, Yoon JH, Kim SB, Kim GY, Kim MK

Despite the coronavirus disease 2019 (COVID-19) vaccination roll-out, variant-related outbreaks have occurred repeatedly in Korea. Although public hospitals played a major role in COVID-19 patients’ care, difficulty incorporating evolving COVID-19...
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Mutational Analysis of Triple-Negative Breast Cancer Using Targeted Kinome Sequencing

Yoo TK, Lee WS, Kim J, Kim MK, Park IA, Kim JH, Han W

Purpose: Triple-negative breast cancer (TNBC) does not have defined therapeutic targets and is currently treated with chemotherapy only. Kinase dysregulation triggers cancer cell proliferation and metastasis and is a crucial...
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Cumulative Recurrence Rate and Risk Factors for Recurrent Abdominal Wall Endometriosis after Surgical Treatment in a Single Institution

Kim SJ, Choi SH, Won S, Shim S, Lee N, Kim M, Kim MK, Seong SJ, Kim ML

Purpose: This study aimed to evaluate the cumulative recurrence rate and risk factors for recurrent abdominal wall endometriosis (AWE) after surgical treatment. Materials and Methods: A retrospective cohort study was conducted...
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Bone regeneration effect of lidocaine–maltodextrin–thrombin collagen on rat calvarial bone defect model

Lee JH, Kim MK, Park YW

We evaluated the effects of lidocaine–maltodextrin–thrombin (LMT) collagen on new bone formation on a rat calvarial defect model. Thirty-six rats were randomly divided into three groups. A single bone window was...
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Comparing Perceptions, Determinants, and Needs of Patients, Family Members, Nurses, and Physicians When Making Life-Sustaining Treatment Decisions for Patients with Hematologic Malignancies

Kim S, Ham EH, Kim DY, Jang SN, Kim Mk, Choi HA, Cho YA, Lee SA, Yun MJ

Purpose: This descriptive study compared the perceptions, determinants, and needs of patients, family members, nurses, and physicians regarding life-sustaining treatment decisions for patients with hematologic malignancies in the hematology-oncology department...
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Booster BNT162b2 COVID-19 Vaccination Increases Neutralizing Antibody Titers Against the SARS-CoV-2 Omicron Variant in Both Young and Elderly Adults

Um J, Choi YY, Kim G, Kim MK, Lee KS, Sung HK, Kim BC, Lee Yk, Jang HC, Bang JH, Chung Kh, Oh Md, Park JS, Jeon J

Concerns about the effectiveness of current vaccines against the rapidly spreading severe acute respiratory syndrome-coronavirus-2 omicron (B.1.1.529) variant are increasing. This study aimed to assess neutralizing antibody activity against the...
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Cardiovascular Risk Is Elevated in Lean Subjects with Nonalcoholic Fatty Liver Disease

Kim Y, Han E, Lee JS, Lee HW, Kim BK, Kim MK, Kim HS, Park JY, Kim DY, Ahn SH, Lee BW, Kang ES, Cha BS, Lee Yh, Kim SU

Background/Aims: Nonalcoholic fatty liver disease (NAFLD) and obesity are independently associated with an increased risk for atherosclerotic cardiovascular disease (ASCVD), the leading cause of mortality in patients with NAFLD. Many...
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Structural Equation Modeling on Spiritual Nursing Care of Clinical Nurses Based on the Theory of Planned Behavior

Lee S, Kim MK, Hong EY, Lee JJ, Kim HJ, Kim HS, Kim DY, Park RH, Ban JY, Park MH, Yun SH, Lim SJ

Purpose The purpose of this study was to construct and test a hypothetical model of clinical nurses’ spiritual nursing care based on the theory of planned behavior. Methods From May 1 to May...
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Delayed Influenza Treatment in Children With False-Negative Rapid Antigen Test: A Retrospective Single-Center Study in Korea 2016–2019

Lee JY, Baek SH, Ahn JG, Yoon SH, Kim MK, Kim SY, Kim KW, Sohn MH, Kang JM

Background: We aimed to examine the delay in antiviral initiation in rapid antigen test (RAT) false-negative children with influenza virus infection and to explore the clinical outcomes. We additionally conducted...
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Intracerebral Hemorrhage Caused by Thrombosis of a Developmental Venous Anomaly with an Unusual Structure: A Case Report

Lee S, Kim DY, Kim MK, Kim HJ

Developmental venous anomalies (DVAs) are common intracranial vascular malformations and they are generally do not cause clinical complications. In cases showing DVA and hemorrhage, the hemorrhage is usually associated with...
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The Effect of the Shift Work on Drinking and the Mediating Effect of Sleep

Jeong H, Kong JS, Kim MK, Kim SH

Objectives:Shift work has been known to cause various health problems by making it difficult for humans to adapt to their natural circadian rhythms. In particular, shift workers tend to complain...
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Association of Resting Heart Rate and Dyslipidemia and Diabetes in 2018 National Health and Nutrition Examination Survey

Heo AS, Lee JC, Kim MK

Background: As a risk factor for diabetes, there are many evidences for physical characteristics and lifestyle habits. There are studies showing that resting heart rate is also related, but evidence...
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A Randomized Controlled Trial for Doing vs. Omitting Intraoperative Frozen Section Biopsy for Resection Margin Status in Selected Patients Undergoing Breast-Conserving Surgery (OFF-MAP Trial)

Yoo TK, Kang YJ, Jeong J, Song JY, Kang SH, Lee HY, Kim ET, Yi O, Lee HB, Choi S, Park HS, Gwak G, Kim JI, Kim MK, Lee J, Kang HJ, Chae BJ

Purpose: Intraoperative frozen section biopsy is used to reduce the margin positive rate and re-excision rate and has been reported to have high diagnostic accuracy. A majority of breast surgeons...
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Safety Monitoring after the BNT162b2 COVID-19 Vaccine among Adults Aged 75 Years or Older

Choi YY, Kim MK, Kwon HC, Kim GH

Background: Older adults are given high priority for coronavirus disease 2019 (COVID-19) vaccination; however, little is known about the safety of vaccines. This study was conducted to examine the safety...
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Effect of Quality Control Program in Surgical Management of Early Cervical Cancer

Shim JE, Kim MK, Kim YH, Kim SC

Background: Regular assessments of clinical performance in gynecologic cancer surgery is important for the safety of patients. We evaluated the effects of quality control (QC) program on the treatment pattern...
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