Nucl Med Mol Imaging.
2009 Aug;43(4):352-356.
Diffuse Bone Marrow Uptake of 99mTc-MIBI in A Case of Intravascular Large B-cell Lymphoma
- Affiliations
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- 1Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea. paengjc@snu.ac.kr
- 2Department of Pathology, Seoul National University College of Medicine, Seoul, Korea.
Abstract
- Intravascular large B-cell lymphoma (IVLBCL) is a subtype of diffuse large cell lymphoma, characterized by proliferation of lymphoid cells in the intravascular space of various organs without causing a mass effect. Although 18F-FDG PET is a powerful imaging tool in lymphoma, the usefulness of 18F-FDG PET in the assessment of IVLBCL is still controversial. 99mTc-MIBI, a tumor imaging radiopharmaceutical with a different mechanism from that of 18F-FDG, has been reported to be also effective in lymphoma. However, there is nearly no report on the efficacy of 99mTc-MIBI in the assessment of IVLBCL. We present one case of IVLBCL that showed 99mTc-MIBI accumulation in the involved bone marrow as an incidental finding, which was discrepant from that of 18F-FDG PET.
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