Korean J Dermatol.  2004 Feb;42(2):223-225.

A Case of Intravascular Large B Cell Lymphoma

Affiliations
  • 1Department of Dermatology, Kangbuk Samsung Hospital, School of Medicine, Sungkyunkwan University, Seoul, Korea.

Abstract

Intravascular large cell lymphoma (angiotropic large cell lymphoma) is a rare, multifocal, intravascular neoplasm of lymphoid cells that preferentially involves the vasculature of the skin and central nervous system. We report a 33-year-old man who had asymptomatic purpuric patches on both thighs, left arm, and left flank. A biopsy specimen showed intravascular collections of tumor cells with irregular nuclear contour and prominent nucleoli. These cells were positive for CD45, CD20, but negative for CD3, and CD56. The clinicopathologic features and immunohistochemical profiles were diagnostic of intravasculr large B cell lymphoma.

Keyword

Large B cell lymphoma; Intravascular

MeSH Terms

Adult
Arm
Biopsy
Central Nervous System
Humans
Lymphocytes
Lymphoma
Lymphoma, B-Cell*
Skin
Thigh
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