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Clinical Relevance of Enlarged Perivascular Spaces in Neurodegenerative Disease

Je YR, Ham HG, Park YH, Kim TY, Go Ms, Lee HI, Kim DE, Jung NY, Lee MJ, Seo SW, Kim EJ

Background: Enlarged perivascular space (ePVS) is recently reported to be associated with cerebral small vessel disease (SVD) and Alzheimer’s disease (AD). The topographical location of ePVS may relate to the...
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Trichofolliculoma in the Medial Canthal Area

Jeong IS, Kim SJ, Seo SW

Purpose: We report a case of trichofolliculoma located in the medial canthal area that was initially clinically suspected to be basal cell carcinoma. Case summary: A 93-year-old female patient presented to...
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Virtual Global Collaboration to Advocate Students for Pharmacy Immunizations during Coronavirus Disease-19

Rhie SJ, Truong HA, Seo SW

Background: It was to describe collaborative educational efforts under Coronavirus disease 2019 period to advocate pharmacybased immunization delivery and meet unmet needs of...
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Annual Report of the Korean External Quality Assessment Service on General Transfusion Medicine and General Transfusion Antibody Tests (2022)

Kim HJ, Kim JS, Seo SW, Kim H, Cho D, Ko DH

This report summarizes the 2022 survey results of the external quality assessment (EQA) scheme for the general transfusion medicine tests and general transfusion antibody test programs in Korea. Proficiency testing...
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Intravascular Large B-cell Lymphoma Presenting as Rapidly Progressive Encephalopathy

Seo SW, Lee J, Lee JH, Kim MK, Yoo BG, Kim H

Intravascular large B-cell lymphoma (IVLBCL) is a rare form of non-Hodgkin’s lymphoma that selectively involves the lumina of vessels, and may present as ischemic stroke. A 62-year-old man presented with...
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Tau positron emission tomography in tauopathies: A narrative review

Lee H, Gu Y, Seo SW, Moon SH

Aggregation of misfolded tau in the brain is a major pathological feature common in various neurodegenerative disorders known as tauopathies, including Alzheimer’s disease, progressive supranuclear palsy, corticobasal syndrome, and dementia...
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White Matter Lesions Predominantly Located in Deep White Matter Represent Embolic Etiology Rather Than Small Vessel Disease

Jung YH, Park S, Lee NK, Han HJ, Jang H, Kim HJ, Seo SW, Na DL

Background and Purpose: We investigated the correlation between the deep distribution of white matter hyperintensity (WMH) (dWMH: WMH in deep and corticomedullary areas, with minimal periventricular WMH) and a positive...
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The Need for Joint IRB in Multi-Clinical Trials and Searching for A Systemization Strategy for IRB Review

Lee MH, Kim YJ, Seo SW

Purpose : Recently, with the development of science and technology and the expansion of research scale, the number of multicenter clinical trials involving more than one institution is increasing. Accordingly,...
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Association of inflammatory complications following resection and immediate reconstruction with soft tissue sarcoma recurrence

Kim J, Mun GH, Seo SW, Lee KT

Purpose: Wide excision and subsequent reconstruction of the defect are crucial pillars in the treatment of soft tissue sarcoma (STS); however, those procedures carry a relatively high risk of postoperative...
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[ 18 F]THK-5351 PET Patterns in Patients With Alzheimer’s Disease and Negative Amyloid PET Findings

Oh M, Oh JS, Oh SJ, Lee SJ, Roh JH, Kim WR, Seo HE, Kang JM, Seo SW, Lee JH, Na DL, Noh Y, Kim JS

Background and Purpose Alzheimer’s disease (AD) does not always mean amyloid positivity. [ 18 F]THK-5351 has been shown to be able to detect reactive astrogliosis as well as tau accompanied...
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Impact of discharge against medical advice on emergency department revisits and prognosis among pneumonia patients recommended to be hospitalized in a general ward

Seo MH, Sung WY, Lee JY, Lee WS, Seo SW, Lee KT

  • KMID: 2531594
  • J Korean Soc Emerg Med.
  • 2022 Apr;33(2):172-183.
Objective: This study examined the clinical consequences of a discharge against medical advice (DAMA) among pneumonia patients recommended to be hospitalized in a general ward and identified the risk factors...
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18F-THK5351 PET Positivity and Longitudinal Changes in Cognitive Function in β-Amyloid-Negative Amnestic Mild Cognitive Impairment

Chun MY, Lee J, Jeong JH, Roh JH, Oh SJ, Oh M, Oh JS, Kim JS, Moon SH, Woo Sy, Kim YJ, Choe YS, Kim HJ, Na DL, Jang H, Seo SW

Purpose: Neuroinflammation is considered an important pathway associated with several diseases that result in cognitive decline. 18F-THK5351 positron emission tomography (PET) signals might indicate the presence of neuroinflammation, as well...
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The impact of the COVID-19 pandemic on emergency department length of stay and outcomes of pneumonia patients

Ha JS, Seo SW, Lee JY, Lee WS, Sung WY, Lee KT

  • KMID: 2527383
  • J Korean Soc Emerg Med.
  • 2022 Feb;33(1):84-93.
Objective: This study aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) outbreak on the emergency department length of stay (ED-LOS) and outcomes of patients admitted with pneumonia. Methods:...
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Baseline Clinical and Biomarker Characteristics of Biobank Innovations for Chronic Cerebrovascular Disease With Alzheimer’s Disease Study: BICWALZS

Roh HW, Kim NR, Lee Dg, Cheong JY, Seo SW, Choi SH, Kim EJ, Cho SH, Kim BC, Kim SY, Kim EY, Chang J, Lee SY, Yoon D, Choi JW, An YS, Kang HY, Shin H, Park B, Son SJ, Hong CH

Objective We aimed to present the study design and baseline cross-sectional participant characteristics of biobank innovations for chronic cerebrovascular disease with Alzheimer’s disease study (BICWALZS) participants. Methods A total of 1,013...
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Developing a Dementia Platform Databank Using Multiple Existing Cohorts

Kang M, Cheon BK, Hahn MJ, Seo SW, Cho J, Shin SY, Na DL, Cho J, Choi SH, Kang D

This study was conducted as a pilot project to evaluate the feasibility of building an integrate dementia platform converging preexisting dementia cohorts from several variable levels. The following four cohorts...
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Autonomic instability in severe tetanus: a case report

Seo SW, Lee J, Yoo BG, Kim J, Huh SY

Tetanus is an infectious disease of the nervous system caused by Clostridium tetani, and is characterized by tonic muscle contractions, painful spasms, and autonomic dysfunction. Severe autonomic dysfunction associated with...
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Endophthalmitis and Retinal Detachment after Ocular Injury by Animal Inoculation Needle

Kwon L, Cho YW, Seo SW, Kim SJ, Chung IY, Yoo WS

Purpose: To report a case of endophthalmitis and retinal detachment after injury caused by an animal inoculation needle. Case summary: A 39-year-old man received an injury to his left eye...
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Two cases of non-fluent variant primary progressive aphasia with different pathological diagnoses

Hwangbo S, Hwang S, Suh MK, Kim SJ, Kim Y, Kim HJ, Na DL, Seo SW, Suh YL

Non-fluent variant primary progressive aphasia (nfvPPA), a subtype of frontotemporal lobar dementia syndrome, has been proven to have various pathological diagnoses. A 63-year-old woman and 71-year-old man separately visited our...
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Effects of Electrical Automatic Massage on Cognition and Sleep Quality in Alzheimer’s Disease Spectrum Patients: A Randomized Controlled Trial

Kim YJ, Kim HR, Jung YH, Park YH, Seo SW

Purpose: Muscle relaxation following electrical automatic massage (EAM) has been found to reduce fatigue, depression, stress, anxiety, and pain in individuals with various conditions. However, the effects of EAM have...
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Microvasculature and Nerve Fiber Layer-Ganglion Cell Inner Plexiform Layer Thickness in Type 2 Diabetes

Seo JS, Cho YW, Seo SW, Kim SJ, Chung IY, Yoo WS

Purpose: To investigate thickness of the nerve fiber layer-ganglion cell inner plexiform layer (NFL-GCIPL) complex and vessel density of the superficial and deep retinal vessels and choriocapillaris using swept source...
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