2. Conrad R, Wegener I, Geiser F, Kleiman A. 2013; Temperament, character, and personality disorders in chronic pain. Curr Pain Headache Rep. 17:318. DOI:
10.1007/s11916-012-0318-3. PMID:
23338770.
Article
3. Radat F, Margot-Duclot A, Attal N. 2013; Psychiatric co-morbidities in patients with chronic peripheral neuropathic pain: a multicentre cohort study. Eur J Pain. 17:1547–1557. DOI:
10.1002/j.1532-2149.2013.00334.x. PMID:
23720357.
Article
5. Mahajan GJ, Vallender EJ, Garrett MR, Challagundla L, Overholser JC, Jurjus G, Dieter L, Syed M, Romero DG, Benghuzzi H, Stockmeier CA. 2018; Altered neuro-inflammatory gene expression in hippocampus in major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 82:177–186. DOI:
10.1016/j.pnpbp.2017.11.017. PMID:
29175309. PMCID:
PMC5801125.
Article
6. Wang YL, Han QQ, Gong WQ, Pan DH, Wang LZ, Hu W, Yang M, Li B, Yu J, Liu Q. 2018; Microglial activation mediates chronic mild stress-induced depressive- and anxiety-like behavior in adult rats. J Neuroinflammation. 15:21. DOI:
10.1186/s12974-018-1054-3. PMID:
29343269. PMCID:
PMC5773028.
Article
7. Lei Y, Chen CJ, Yan XX, Li Z, Deng XH. 2017; Early-life lipopolysaccharide exposure potentiates forebrain expression of NLRP3 inflammasome proteins and anxiety-like behavior in adolescent rats. Brain Res. 1671:43–54. DOI:
10.1016/j.brainres.2017.06.014. PMID:
28655515.
Article
8. Liu S, Liu YP, Song WB, Song XJ. 2013; EphrinB-EphB receptor signaling contributes to bone cancer pain via Toll-like receptor and proinflammatory cytokines in rat spinal cord. Pain. 154:2823–2835. DOI:
10.1016/j.pain.2013.08.017. PMID:
23973554.
Article
9. Cheng Y, Pardo M, Armini RS, Martinez A, Mouhsine H, Zagury JF, Jope RS, Beurel E. 2016; Stress-induced neuroinflammation is mediated by GSK3-dependent TLR4 signaling that promotes susceptibility to depression-like behavior. Brain Behav Immun. 53:207–222. DOI:
10.1016/j.bbi.2015.12.012. PMID:
26772151. PMCID:
PMC4783243.
Article
10. Zhou YX, Gong XH, Zhang H, Peng C. 2020; A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects. Biomed Pharmacother. 130:110505. DOI:
10.1016/j.biopha.2020.110505. PMID:
32682112.
Article
11. Wang D, Liu L, Li S, Wang C. 2018; Effects of paeoniflorin on neurobehavior, oxidative stress, brain insulin signaling, and synaptic alterations in intracerebroventricular streptozotocin-induced cognitive impairment in mice. Physiol Behav. 191:12–20. DOI:
10.1016/j.physbeh.2018.03.016. PMID:
29572012.
Article
13. Gu X, Cai Z, Cai M, Liu K, Liu D, Zhang Q, Tan J, Ma Q. 2016; Protective effect of paeoniflorin on inflammation and apoptosis in the cerebral cortex of a transgenic mouse model of Alzheimer's disease. Mol Med Rep. 13:2247–2252. DOI:
10.3892/mmr.2016.4805. PMID:
26796245.
Article
14. Zhou J, Wang L, Wang J, Wang C, Yang Z, Wang C, Zhu Y, Zhang J. 2016; Paeoniflorin and albiflorin attenuate neuropathic pain via MAPK pathway in chronic constriction injury rats. Evid Based Complement Alternat Med. 2016:8082753. DOI:
10.1155/2016/8082753. PMID:
27429639. PMCID:
PMC4939188.
Article
15. Yin D, Liu YY, Wang TX, Hu ZZ, Qu WM, Chen JF, Cheng NN, Huang ZL. 2016; Paeoniflorin exerts analgesic and hypnotic effects via adenosine A1 receptors in a mouse neuropathic pain model. Psychopharmacology (Berl). 233:281–293. DOI:
10.1007/s00213-015-4108-6. PMID:
26514553.
Article
16. Hu B, Xu G, Zhang X, Xu L, Zhou H, Ma Z, Shen X, Zhu J, Shen R. 2018; Paeoniflorin attenuates inflammatory pain by inhibiting microglial activation and Akt-NF-κB signaling in the central nervous system. Cell Physiol Biochem. 47:842–850. DOI:
10.1159/000490076. PMID:
29807368.
Article
17. Benbouzid M, Pallage V, Rajalu M, Waltisperger E, Doridot S, Poisbeau P, Freund-Mercier MJ, Barrot M. 2008; Sciatic nerve cuffing in mice: a model of sustained neuropathic pain. Eur J Pain. 12:591–599. DOI:
10.1016/j.ejpain.2007.10.002. PMID:
18006342.
Article
18. Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL. 1994; Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods. 53:55–63. DOI:
10.1016/0165-0270(94)90144-9. PMID:
7990513.
Article
19. Wang Z, Huang H, Yang S, Huang S, Guo J, Tang Q, Qi F. 2016; Long-term effect of ropivacaine nanoparticles for sciatic nerve block on postoperative pain in rats. Int J Nanomedicine. 11:2081–2090. DOI:
10.2147/IJN.S101563. PMID:
27274236. PMCID:
PMC4876796.
20. Schneiderhan J, Orizondo C. 2017; Chronic pain: how to approach these 3 common conditions. J Fam Pract. 66:145–157. PMID:
28249053.
21. Gustorff B, Dorner T, Likar R, Grisold W, Lawrence K, Schwarz F, Rieder A. 2008; Prevalence of self-reported neuropathic pain and impact on quality of life: a prospective representative survey. Acta Anaesthesiol Scand. 52:132–136. DOI:
10.1111/j.1399-6576.2007.01486.x. PMID:
17976220.
Article
22. Kuthati Y, Lin SH, Chen IJ, Wong CS. 2019; Melatonin and their analogs as a potential use in the management of Neuropathic pain. J Formos Med Assoc. 118:1177–1186. DOI:
10.1016/j.jfma.2018.09.017. PMID:
30316678.
Article
24. Qiu FM, Zhong XM, Mao QQ, Huang Z. 2013; Antidepressant-like effects of paeoniflorin on the behavioural, biochemical, and neurochemical patterns of rats exposed to chronic unpredictable stress. Neurosci Lett. 541:209–213. DOI:
10.1016/j.neulet.2013.02.029. PMID:
23481217.
Article
25. Nam KN, Yae CG, Hong JW, Cho DH, Lee JH, Lee EH. 2013; Paeoniflorin, a monoterpene glycoside, attenuates lipopolysaccharide-induced neuronal injury and brain microglial inflammatory response. Biotechnol Lett. 35:1183–1189. DOI:
10.1007/s10529-013-1192-8. PMID:
23559368.
Article
26. Wu YM, Jin R, Yang L, Zhang J, Yang Q, Guo YY, Li XB, Liu SB, Luo XX, Zhao MG. 2013; Phosphatidylinositol 3 kinase/protein kinase B is responsible for the protection of paeoniflorin upon H₂O₂-induced neural progenitor cell injury. Neuroscience. 240:54–62. DOI:
10.1016/j.neuroscience.2013.02.037. PMID:
23485815.
27. Nguyen L, Kakeda S, Katsuki A, Sugimoto K, Otsuka Y, Ueda I, Igata R, Watanabe K, Kishi T, Iwata N, Korogi Y, Yoshimura R. 2019; Relationship between VEGF-related gene polymorphisms and brain morphology in treatment-naïve patients with first-episode major depressive disorder. Eur Arch Psychiatry Clin Neurosci. 269:785–794. DOI:
10.1007/s00406-018-0953-8. PMID:
30406404.
Article
28. Taylor WD, Deng Y, Boyd BD, Donahue MJ, Albert K, McHugo M, Gandelman JA, Landman BA. 2020; Medial temporal lobe volumes in late-life depression: effects of age and vascular risk factors. Brain Imaging Behav. 14:19–29. DOI:
10.1007/s11682-018-9969-y. PMID:
30251182. PMCID:
PMC6431585.
Article
29. Mutso AA, Radzicki D, Baliki MN, Huang L, Banisadr G, Centeno MV, Radulovic J, Martina M, Miller RJ, Apkarian AV. 2012; Abnormalities in hippocampal functioning with persistent pain. J Neurosci. 32:5747–5756. DOI:
10.1523/JNEUROSCI.0587-12.2012. PMID:
22539837. PMCID:
PMC3365570.
Article
31. Burston JJ, Valdes AM, Woodhams SG, Mapp PI, Stocks J, Watson DJG, Gowler PRW, Xu L, Sagar DR, Fernandes G, Frowd N, Marshall L, Zhang W, Doherty M, Walsh DA, Chapman V. 2019; The impact of anxiety on chronic musculoskeletal pain and the role of astrocyte activation. Pain. 160:658–669. DOI:
10.1097/j.pain.0000000000001445. PMID:
30779717. PMCID:
PMC6407811.
Article
32. Ünal Ö, Akyol Y, Tander B, Ulus Y, Terzi Y, Kuru Ö. 2019; The relationship of illness perceptions with demographic features, pain severity, functional capacity, disability, depression, and quality of life in patients with chronic low back pain. Turk J Phys Med Rehabil. 65:301–308. DOI:
10.5606/tftrd.2019.3248. PMID:
31893266. PMCID:
PMC6935732.
Article
34. Dellarole A, Morton P, Brambilla R, Walters W, Summers S, Bernardes D, Grilli M, Bethea JR. 2014; Neuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signaling. Brain Behav Immun. 41:65–81. DOI:
10.1016/j.bbi.2014.04.003. PMID:
24938671. PMCID:
PMC4167189.
Article
36. Mika J, Zychowska M, Popiolek-Barczyk K, Rojewska E, Przewlocka B. 2013; Importance of glial activation in neuropathic pain. Eur J Pharmacol. 716:106–119. DOI:
10.1016/j.ejphar.2013.01.072. PMID:
23500198.
Article
37. Krabbe KS, Reichenberg A, Yirmiya R, Smed A, Pedersen BK, Bruunsgaard H. 2005; Low-dose endotoxemia and human neuropsychological functions. Brain Behav Immun. 19:453–460. DOI:
10.1016/j.bbi.2005.04.010. PMID:
15963684.
Article
38. Chen J, Wang Z, Zheng Z, Chen Y, Khor S, Shi K, He Z, Wang Q, Zhao Y, Zhang H, Li X, Li J, Yin J, Wang X, Xiao J. 2017; Neuron and microglia/macrophage-derived FGF10 activate neuronal FGFR2/PI3K/Akt signaling and inhibit microglia/macrophages TLR4/NF-κB-dependent neuroinflammation to improve functional recovery after spinal cord injury. Cell Death Dis. 8:e3090. DOI:
10.1038/cddis.2017.490. PMID:
28981091. PMCID:
PMC5682656.
Article
39. Zhou Z, Lin J, Huo R, Huang W, Zhang J, Wang L, Sun Y, Shen B, Li N. 2012; Total glucosides of paeony attenuated functional maturation of dendritic cells via blocking TLR4/5 signaling in vivo. Int Immunopharmacol. 14:275–282. DOI:
10.1016/j.intimp.2012.07.012. PMID:
22846756.
Article
40. Wium-Andersen MK, Ørsted DD, Nielsen SF, Nordestgaard BG. 2013; Elevated C-reactive protein levels, psychological distress, and depression in 73, 131 individuals. JAMA Psychiatry. 70:176–184. DOI:
10.1001/2013.jamapsychiatry.102. PMID:
23266538.
41. Dahl J, Ormstad H, Aass HC, Malt UF, Bendz LT, Sandvik L, Brundin L, Andreassen OA. 2014; The plasma levels of various cytokines are increased during ongoing depression and are reduced to normal levels after recovery. Psychoneuroendocrinology. 45:77–86. DOI:
10.1016/j.psyneuen.2014.03.019. PMID:
24845179.
Article