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Coactosin-like protein 1 inhibits neuronal migration during mouse corticogenesis

Li G, Yin Y, Chen J, Fan Y, Ma J, Huang Y, Chen C, Dai P, Chen S, Zhao S

Coactosin-like protein 1 (Cotl1), a member of the actin-depolymerizing factor (ADF)/cofilin family, was first purified from a soluble fraction of Dictyostelium discoideum cells. Neuronal migration requires cytoskeletal remodeling and actin...
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A Novel Homozygous CAPN1 Pathogenic Variant in a Chinese Patient with Pure Hereditary Spastic Paraplegia

Chen Y, Cen Z, Zheng X, Xie F, Chen S, Luo W

No abstract available.
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Encephalitic Episodes Followed by Leukoencephalopathy: A Novel Indication for Neuronal Intranuclear Inclusion-Body Disease

Zhou L, Chen S, Liu J, Luan X

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Cortical Deafness and Tinnitus Following Sequential Bilateral Putaminal Hemorrhage

Yang S, Chen S, Zhu J, Han X

No abstract available.
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A Prospective Study of the Surgical Outcome of Simple Uvulopalatopharyngoplasty (UPPP), UPPP Combined With Genioglossus Advancement or Tongue Base Advancement for Obstructive Sleep Apnea Hypopnea Syndrome Patients With Multilevel Obstruction

Chen S, Shi S, Xia Y, Zhu M, Zhang C, Xia S, Zheng H

The editorial board and publication ethics committee of the CEO decided to retract this paper from our journal.
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LETM1 Promotes Gastric Cancer Cell Proliferation, Migration, and Invasion via the PI3K/Akt Signaling Pathway

Zhang Y, Chen L, Cao Y, Chen S, Xu C, Xing J, Zhang K

Purpose: Globally, there is a high incidence of gastric cancer (GC). Leucine zipper-EF-hand containing transmembrane protein 1 (LETM1) is reported to play a vital role in several human malignancies. However,...
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Toll-like Receptor 4 Deficiency Aggravates Airway Hyperresponsiveness and Inflammation by Impairing Neutrophil Apoptosis in a Toluene Diisocyanate-Induced Murine Asthma Model

Chen S, Deng Y, He Q, Chen Y, Wang D, Sun W, He Y, Zou Z, Liang Z, Chen R, Yao L, Tao A

Purpose: Accumulating evidence has suggested that toll-like receptor 4 (TLR4) is critically involved in the pathogenesis of asthma. The aim of this study was to investigate the role of TLR4...
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Non-invasive evaluation of testicular torsion using ultrasound shear wave elastography: an experimental study

Lin Y, Lu W, Li G, Mao L, Ouyang L, Zhu Z, Chen S, Liang P, Jin H, Gao L, Liang J, Qiu S, Chen F

Purpose: The goal of this study was to examine changes in testicular stiffness at various intervals after the induction of testicular torsion, as well as to assess the predictive value...
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Cerebellar Structural Abnormality in Autism Spectrum Disorder: A Magnetic Resonance Imaging Study

Lu Q, Chen J, Wang Y, Huang L, Jiang Z, Nguchu BA, Chen S, Qiu B, Wang X

Objective This study uses structural magnetic resonance imaging to explore changes in the cerebellar lobules in patients with autism spectrum disorder (ASD) and further analyze the correlation between cerebellar structural...
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Apoptosis induced in vivo by new type gosling viral enteritis virus

Chen S, Cheng A, Wang M, Zhu D, Jia R, Luo Q, Cui H, Zhou Y, Wang Y, Xu Z, Chen Z, Chen X, Wang X

In this study, apoptosis was induced by new type gosling viral enteritis virus (NGVEV) in experimentally infected goslings is reported in detail for the first time. After 3-day-old goslings were...
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Molecular characterization of duck enteritis virus CHv strain UL49.5 protein and its colocalization with glycoprotein M

Lin M, Jia R, Wang M, Gao X, Zhu D, Chen S, Liu M, Yin Z, Wang Y, Chen X, Cheng A

The UL49.5 gene of most herpesviruses is conserved and encodes glycoprotein N. However, the UL49.5 protein of duck enteritis virus (DEV) (pUL49.5) has not been reported. In the current study,...
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Patient Response to Endoscopic Therapy for Gastroesophageal Varices Based on Endoscopic Ultrasound Findings

Tseng Y, Ma L, Luo T, Zeng X, Li F, Li N, Wei Y, Chen S

BACKGROUND/AIMS: Gastroesophageal variceal hemorrhage is a common complication of portal hypertension. Endoscopic therapy is currently recommended for preventing gastroesophageal variceal rebleed. However, the rate of variceal rebleed and its associated...
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Serum MicroRNA Levels as a Noninvasive Diagnostic Biomarker for the Early Diagnosis of Hepatitis B Virus-Related Liver Fibrosis

Bao S, Zheng J, Li N, Huang C, Chen M, Cheng Q, Yu K, Chen S, Zhu M, Shi G

BACKGROUND/AIMS: To investigate the role of selected serum microRNA (miRNA) levels as potential noninvasive biomarkers for differentiating S0–S2 (early fibrosis) from S3–S4 (late fibrosis) in patients with a chronic hepatitis...
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Impact of Chronic Lateral Ankle Instability with Lateral Collateral Ligament Injuries on Biochemical Alterations in the Cartilage of the Subtalar and Midtarsal Joints Based on MRI T2 Mapping

Tao H, Hu Y, Lu R, Zhang Y, Xie Y, Chen T, Chen S

Objective: To quantitatively assess biochemical alterations in the cartilage of the subtalar and midtarsal joints in chronic lateral ankle instability (CLAI) patients with isolated anterior talofibular ligament (ATFL) injuries and...
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Screening Tools Based on Nomogram for Diabetic Kidney Diseases in Chinese Type 2 Diabetes Mellitus Patients

Wang G, Wang B, Qiao G, Lou H, Xu F, Chen Z, Chen S

Background: The influencing factors of diabetic kidney disease (DKD) in Chinese patients with type 2 diabetes mellitus (T2DM) were explored to develop and validate a DKD diagnostic tool based on...
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Impact of Cardiovascular Disease on Health Insurance Coverage and Healthcare Use under Economic Stress: The National Health and Nutrition Examination Survey, 2003–2012

Li J, Lai H, Chen D, Chen S, Lai S

OBJECTIVES: Cardiovascular disease (CVD) has a substantial financial impact on healthcare systems in the US. This study aimed to examine the impact of CVD on health insurance coverage and health...
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The Prognostic Value of Treatment-Related Lymphopenia in Nasopharyngeal Carcinoma Patients

Liu LT, Chen QY, Tang LQ, Guo SS, Guo L, Mo HY, Chen MY, Zhao C, Guo X, Qian CN, Zeng MS, Bei JX, Tan J, Chen S, Hong MH, Shao JY, Sun Y, Ma J, Mai HQ

PURPOSE: This study was conducted to evaluate the prognostic value of treatment-related lymphopenia in patients with nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS: A total of 413 consecutive stage II-IVb NPC patients...
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Bcl11b Regulates IL-17 Through the TGF-β/Smad Pathway in HDM-Induced Asthma

Chen S, Han Y, Chen H, Wu J, Zhang M

PURPOSE: T helper (Th) 17 cells play a critical role in the development of asthma, but the underlying mechanism of how interleukin (IL)-17 is regulated in allergic airway inflammation is...
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Achalasia: The Current Clinical Dilemma and Possible Pathogenesis

Jia X, Chen S, Zhuang Q, Tan N, Zhang M, Cui Y, Wang J, Xing X, Xiao Y

  • KMID: 2541566
  • J Neurogastroenterol Motil.
  • 2023 Apr;29(2):145-155.
  • doi: 10.5056/jnm22176
Achalasia is a primary esophageal motility disorder manifested by dysphagia and chest pain that impair patients’ quality of life, and it also leads to chronic esophageal inflammation by food retention...
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Diagnosis of Seronegative Rheumatoid Arthritis by  68  Ga‑FAPI PET/CT

Cheung S, Chen S, Wong Y, Wu K, Ho C

Early diagnosis of rheumatoid arthritis with the initiation of disease-modifying antirheumatic drugs is important to prevent future disability. Seronegative rheumatoid arthritis lacks the classical immunological markers, thus imposing clinical diagnostic...
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