- Xylazole inhibits NO-cGMP pathway in fetal rat nerve cells
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Wang X, Wu Y, Liu L, Bai H, Zhang Z, Zhao M, Ma T, Song X, Jia L, Lv L, Yu Y, Xu X, Chen H, Gao L
- KMID: 2525540
- J Vet Sci.
- 2022 Jan;23(1):e16.
- doi: 10.4142/jvs.21188
Background: Xylazole (Xyl) is a veterinary anesthetic that is structurally and functionally similar to xylazine. However, the effects of Xyl in vitro remain unknown. Objectives: This study aimed to investigate the... -
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- Paeoniflorin ameliorates neuropathic pain-induced depression-like behaviors in mice by inhibiting hippocampal neuroinflammation activated via TLR4/NF-kB pathway
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Bai H, Chen S, Yuan T, Xu D, Cui S, Li X
- KMID: 2514947
- Korean J Physiol Pharmacol.
- 2021 May;25(3):217-225.
- doi: 10.4196/kjpp.2021.25.3.217
Neuropathic pain (NP) that contributes to the comorbidity between pain and depression is a clinical dilemma. Neuroinflammatory responses are known to have potentially important roles in the initiation of NP... -
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- Neoadjuvant Chemotherapy–Guided Bladder-Sparing Treatment for Muscle-Invasive Bladder Cancer: Results of a Pilot Phase II Study
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Shi H, Zhang W, Bi X, Wang D, Xiao Z, Guan Y, Guan K, Tian J, Bai H, Hu L, Cao C, Jiang W, Hu Z, Zhang J, Chen Y, Zheng S, Feng X, Li C, Li Y, Ma J, Liu Y, Zhou A, Shou J
- KMID: 2521590
- Cancer Res Treat.
- 2021 Oct;53(4):1156-1165.
- doi: 10.4143/crt.2020.1356
Purpose Reduced quality of life after cystectomy has made bladder preservation a popular research topic for muscle-invasive bladder cancer (MIBC). Previous research has indicated significant tumor downstaging after neoadjuvant chemotherapy... -
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