Clin Exp Reprod Med.  2019 Mar;46(1):1-7. 10.5653/cerm.2019.46.1.1.

Mesenchymal stem cells for restoration of ovarian function

• Yoon SY

• KMID: 2469600
• DOI: http://doi.org/10.5653/cerm.2019.46.1.1

Abstract

With the progress of regenerative medicine, mesenchymal stem cells (MSCs) have received attention as a way to restore ovarian function. It has been reported that MSCs derived from bone marrow, adipose, umbilical cord blood, menstrual blood, and amniotic fluid improved ovarian function. In light of previous studies and advances in this field, there are increased expectations regarding the utilization of MSCs to restore ovarian function. This review summarizes recent research into potential applications of MSCs in women with infertility or primary ovarian insufficiency, including cases where these conditions are induced by anticancer therapy.

Keyword

Mesenchymal stem cell; Ovarian function

MeSH Terms

Amniotic Fluid
Bone Marrow
Female
Fetal Blood
Humans
Infertility
Mesenchymal Stromal Cells*
Primary Ovarian Insufficiency
Regenerative Medicine