J Wound Manag Res.  2019 Sep;15(2):57-67. 10.22467/jwmr.2019.00731.

Factors Affecting Vascular Clogging, Wound Status and Bacterial Culture in Diabetic Foot Ulcers

Affiliations
  • 1Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea. psjyshin@gmail.com
  • 2Research Institute of Clinical Medicine-Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.

Abstract

BACKGROUND
We assumed that vascular clogging, wound status, and bacterial culture tests are significant characteristics in developing a treatment plan for diabetic patients with foot ulcers. The goal of our study was to find out the potential factors affecting vascular clogging, wound status, and bacterial culture tests in diabetic patients with foot ulcers.
METHODS
The medical records of diabetic patients with foot ulcers presenting at our institution between January 2016 and December 2017 were reviewed. A total of 58 diabetic patients with foot ulcers were included. Patient baseline characteristics including co-morbidities, as well as foot and ulcer characteristics, were analyzed.
RESULTS
By using the univariate and multivariate binary logistic regression analysis, we have found significant factors affecting vascular clogging, wound status and bacterial culture test. Age, glomerular filtration rate (GFR), and glycosylated hemoglobin (HbA1c) were significant factors influencing vascular status. Age, dialysis, GFR, white blood cell (WBC), and osteomyelitis were significant factors influencing wound status. Also, sex (male), dialysis and high WBC affect the possibility of Gram-negative aerobic bacterial infection more so than other bacterial infection.
CONCLUSION
This study has confirmed significant factors affecting vascular status, wound status, and bacterial culture tests, including co-morbidities, as well as foot and ulcer characteristics at baseline. Physicians should consider these factors in developing treatment plans or predicting outcomes of diabetic foot ulcers.

Keyword

Diabetic foot ulcer; Wound classification; Vascular clogging; Bacterial culture

MeSH Terms

Bacterial Infections
Diabetic Foot*
Dialysis
Foot
Foot Ulcer
Glomerular Filtration Rate
Hemoglobin A, Glycosylated
Humans
Leukocytes
Logistic Models
Medical Records
Osteomyelitis
Ulcer*
Wounds and Injuries*
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