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Lovastatin derivative dehydrolovastatin ameliorates ulcerative colitis in mice by suppressing NF-κB and inflammatory cytokine expression

Zhang X, Deng QH, Deng JH, Wang SJ, Chen Q

Ulcerative colitis (UC) is associated with intestinal immune imbalance and inflammatory response. Because dehydrolovastatin (DLVT), a derivative of lovastatin, has been recently shown to inhibit inflammation and relieve immune arthritis...
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The Interrater Agreement for the Assessment of Pressure Ulcer Risk Using the Braden Scale and the Classification of Pressure Ulcers by Nurses in A Medium-Sized Hospital

Na HJ, Yoo SH, Kwon YR, Ahn MJ

PURPOSE: This methodological study was conducted to evaluate the interrater agreement in pressure ulcer risk assessment using the Braden scale, and in pressure ulcer classification, by nurses in a medium-sized...
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Corneal Collagen Cross-linking for Corneal Ulcer from Moraxella Group

Woo SE, Lee SH

PURPOSE: To report a case of corneal collagen cross-linking for corneal ulcer caused by the Moraxella group. CASE SUMMARY: A 77-year-old male had decreased visual acuity for several days in his...
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An Atypical Extraintestinal Manifestation in a Child with Ulcerative Colitis: Cutaneous Leukocytoclastic Vasculitis

Oh SJ, Choi Y, Kim CR, Park JH, Lee JH, Lee DY

No abstract available.
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Effect of Sodium Cromoglycate on Acetic Acid-induced Ulcerative Colitis in Mice

Ghafouri Z, Seyyedian , Nikbakht J, Kouhsari E, Bayat S, Zargar H, Houshmand

BACKGROUND/AIMS: Ulcerative colitis (UC) is a type of inflammatory bowel disease that mainly involves the colon. Thus far, glucocorticoids and amino-salicylate have been the main treatment. METHODS: To assess drugs with...
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Refractory Digital Ulcers Treated by Botulinum Toxin and Endothelin Receptor-1 Antagonist in Anti-MDA5-Antibody-Positive Dermatomyositis

Min HK, Kim HR, Lee SH, Park SH, Oh J, Choi K

No abstract available.
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Comparison of Real-World Outcomes of Infliximab versus Adalimumab in Biologic-Naïve Korean Patients with Ulcerative Colitis: A Population-Based Study

Han M, Jung YS, Cheon JH, Park S

PURPOSE: Data on the comparative effectiveness of infliximab (IFX) or adalimumab (ADA) in patients with ulcerative colitis (UC) are extremely limited, especially in the Asian population. We compared clinically important...
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Diagnosis of Systemic Scleroderma in a Patient with Leg Ulcer

Ju GS, Son KM, Choi WY, Cheon JS

Systemic scleroderma is an autoimmune disease that affects connective tissue in internal organs and the skin with thickening and fibrosis. When afflicting internal organs, the disease leads to reduced quality...
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Epinephrine Infiltration and the Incidence of Bleeding Complications after Surgical Debridement of Pressure Ulcers with Negative Pressure Wound Therapy

Kim YH, Kim H, Cheon JH, Kang DH

BACKGROUND: For reducing intraoperative bleeding, epinephrine is commonly used as a vasoconstrictor with infiltration anesthesia. However, the effects of epinephrine on postoperative bleeding complications are still a matter of debate....
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Efficacy of the Mobile Three-Dimensional Wound Measurement System in Pressure Ulcer Assessment

Jun D, Choi H, Kim J, Lee M, Kim S, Jo D, Kim C, Shin D

BACKGROUND: Clinically assessing the changing status of wounds is important in determining management of pressure ulcers. A mobile three-dimensional measurement system (3DWMS) with a laser-assisted sensor camera was recently introduced...
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Factors Affecting Vascular Clogging, Wound Status and Bacterial Culture in Diabetic Foot Ulcers

Kim JL, Shin JY, Roh SG, Chang SC, Lee NH

BACKGROUND: We assumed that vascular clogging, wound status, and bacterial culture tests are significant characteristics in developing a treatment plan for diabetic patients with foot ulcers. The goal of our...
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Effectiveness of Autologous Platelet-Rich Plasma for the Healing of Ulcers after Endoscopic Submucosal Dissection

Jeong E, Yoo IK, Cakir OO, Kim HK, Kim WH, Hong SP, Cho JY

BACKGROUND/AIMS: Platelet-rich plasma (PRP) has been used for wound healing in various medical fields. The aim of this study was to evaluate the clinical efficacy and safety of local PRP...
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Endoscopic Management of Peptic Ulcer Bleeding: Recent Advances

Chiu PW

Bleeding peptic ulcers remained as one of the commonest causes of hospitalization worldwide. While endoscopic hemostasis serves as primary treatment for bleeding ulcers, rebleeding after endoscopic hemostasis becomes more and...
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A dual padding method for ischial pressure sore reconstruction with an inferior gluteal artery perforator fasciocutaneous flap and a split inferior gluteus maximus muscle flap

Ku I, Lee GK, Yoon S, Jeong E

BACKGROUND: Various surgical management methods have been proposed for ischial sore reconstruction, yet it has the highest recurrence rate of all pressure ulcer types. A novel approach combining the advantages...
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A Case Report of Esophageal Ulceration after Taking Doxycycline

Kim GY, Lee CH, Lee JW, Lee JM, Lee MS, Ji E

Doxycycline is frequently prescribed to treat urogenital infections or acne vulgaris. A 39-year-old man was prescribed doxycycline as a treatment for his skin infection. He took each tablet on an...
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Penetrating Atherosclerotic Ulcers of the Abdominal Aorta: A Case Report and Review of the Literature

Kotsis T, Spyropoulos BG, Asaloumidis N, Christoforou P, Katseni K, Papaconstantinou I

Penetrating atherosclerotic ulcers (PAUs) of the aorta are defined as atherosclerotic lesions with aortic intima and media ulceration, which may lead to a complete rupture of the adventitial wall. The...
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Diffuse Involvement of Primary Colorectal Lymphoma Simulating Ulcerative Colitis

Kim JY, Chang SH, Kim HS, Joo M

Diffuse involvement of colorectal lymphoma masquerading as colitis is a very rare presentation of primary colorectal lymphoma. Detecting occult lymphoma is difficult in the setting of diffuse colonic involvement with...
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Hepatic Hydatid Disease Causing Gastric Ulcer as a Rare Complication

Cho E, Shin SS, Kim GE

Hydatid disease in humans is a parasitic disease typically caused by the larvae of Echinococcus granulosus. Although the disease can occur in any body part, it most frequently affects the...
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Multidrug-resistant Disseminated Tuberculosis Related to Infliximab in a Patient with Ulcerative Colitis and Negative Evaluation for Latent Tuberculosis

Jun YK, Chun J, Kang EA, Lee HJ, Im JP, Kim JS

Anti-tumor necrosis factor (anti-TNF) is an effective biological agent for the treatment of moderate-to-severe active ulcerative colitis (UC) refractory to conventional therapy. On the other hand, anti-TNF therapy is strongly...
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Effects of botulinum toxin injection on systemic sclerosis-related digital ulcers

Souk JW, Kim HS

No abstract available.
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