J Korean Neurol Assoc.  2019 May;37(2):135-143. 10.17340/jkna.2019.2.3.

Fine Dust and Dementia: Is Ambient Air Pollution Associated with Cognitive Health?

• Han SH

• KMID: 2454838
• DOI: http://doi.org/10.17340/jkna.2019.2.3

Abstract

Air pollution is a growing global health concern estimated to contribute to as many as 4.2 million premature deaths worldwide per year. So it poses the greatest environmental risk to human health. A strong and rapidly expanding body of evidence links ambient air pollution to respiratory and cardiovascular conditions that eventually may also affect cognition in the elderly. Among various ambient air pollutants, particulate matter (PM) has been implicated as a chronic source of neuroinflammation and reactive oxygen species that produce neuropathology resulting in neurodevelopmental disorders and neurodegenerative disease. The current review will briefly discuss the clinical features and underlying mechanism of PM induced cognitive dysfunction, more specifically, dementia.

Keyword

Ambient air pollution; Particulate matter; Cognition; Dementia; Alzheimer disease

MeSH Terms

Aged
Air Pollution*
Alzheimer Disease
Cognition
Dementia*
Dust*
Global Health
Humans
Mortality, Premature
Neurodegenerative Diseases
Neurodevelopmental Disorders
Neuropathology
Particulate Matter
Reactive Oxygen Species
Dust
Particulate Matter
Reactive Oxygen Species