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Epithelial PI3K-δ Promotes House Dust Mite-Induced Allergic Asthma in NLRP3 Inflammasome-Dependent and -Independent Manners

Kim SR, Park HJ, Lee KB, Kim HJ, Jeong JS, Cho SH, Lee YC

PURPOSE: Phosphoinositide 3-kinase (PI3K)-δ-dependent Akt activation is known to play critical roles in various immune responses of white blood cells in which PI3K-δ isoform is mostly expressed in contrast to...
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Fine dust and eye health

Choi SY, Eom Y, Song JS, Kim HM

This paper aims to make recommendations for the management of eye health related to fine dust exposure. Fine dust is one of the biggest problems related to air pollution in...
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House Dust Mite Allergy Under Changing Environments

Acevedo N, Zakzuk J, Caraballo

Environmental variations induced by industrialization and climate change partially explain the increase in prevalence and severity of allergic disease. One possible mechanism is the increase in allergen production leading to...
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Evaluation of Matrix Effects in Quantifying Microbial Secondary Metabolites in Indoor Dust Using Ultraperformance Liquid ChromatographeTandem Mass Spectrometer

Jaderson M, Park JH

BACKGROUND: Liquid chromatographyetandem mass spectrometry (LC-MSMS) for simultaneous analysis of multiple microbial secondary metabolites (MSMs) is potentially subject to interference by matrix components. METHODS: We examined potential matrix effects (MEs) in...
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Fine Dust and Dementia: Is Ambient Air Pollution Associated with Cognitive Health?

Han SH

Air pollution is a growing global health concern estimated to contribute to as many as 4.2 million premature deaths worldwide per year. So it poses the greatest environmental risk to...
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Altered Sphingolipid Metabolism Is Associated With Asthma Phenotype in House Dust Mite-Allergic Patients

Kowal K, Żebrowska E, Chabowski

PURPOSE: Sphingolipids play an important role in cell growth, survival, inflammation and tissue remodeling. House dust mite (HDM) allergy is a major risk factor for asthma. The aim of the...
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Lung Function of Grain Millers Exposed to Grain Dust and Diesel Exhaust in Two Food Markets in Ibadan Metropolis, Nigeria

Iyogun K, Lateef SA, Ana GR

BACKGROUND: Despite growing concern over occupational exposure to particulate matter (PM) such as grain dust and diesel exhaust, information about the exposure level and health implications among workers in small-scale...
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Safety of Ultra-rush Schedule of Subcutaneous Allergen Immunotherapy With House Dust Mite Extract Conducted in an Outpatient Clinic in Patients With Atopic Dermatitis and Allergic Rhinitis

Lee SH, Kim ME, Shin YS, Ye YM, Park HS, Nahm DH

PURPOSE: Ultra-rush schedule of subcutaneous allergen immunotherapy (UR-SCIT) administering maximum maintenance dose of allergen extract within one day can save time and effort for allergen immunotherapy in patients with allergic...
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Association Between Organic Dust Exposure and Adult-Asthma: A Systematic Review and Meta-Analysis of Case-Control Studies

Zhang Y, Ye B, Zheng H, Zhang W, Han L, Yuan P, Zhang C

BACKGROUND: Exposure to organic dust has been widely investigated as a potential risk factor for asthma with different results. To clarify a potential relationship, we performed the present meta-analysis to...
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Effects of Ser47-Point Mutation on Conformation Structure and Allergenicity of the Allergen of Der p 2, a Major House Dust Mite Allergen

Kulwanich , Thanyaratsrisakul S, Jirapongsananuruk O, Hales BJ, Thomas WR, Piboonpocanun S

PURPOSE: Hypoallergenic recombinant Der p 2 has been produced by various genetic manipulations, but mutation of a naturally polymorphic amino acid residue known to affect IgE binding has not been...
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Tolerogenic Dendritic Cells Reduce Airway Inflammation in a Model of Dust Mite Triggered Allergic Inflammation

Aragão-França LS, Rocha VC, Cronemberger-Andrade A, Costa FH, Vasconcelos JF, Athanazio , Silva DN, Santos ES, Meira CS, Araújo CF, Cerqueira , Cardillo F, Alcântara-Neves NM, Soares MB, Pontes-de-Carvalho LC

PURPOSE: The use of tolerogenic dendritic cells (TolDCs) to control exacerbated immune responses may be a prophylactic and therapeutic option for application in autoimmune and allergic conditions. The objective of...
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The Impact of Air Pollution, Including Asian Sand Dust, on Respiratory Symptoms and Health-related Quality of Life in Outpatients With Chronic Respiratory Disease in Korea: A Panel Study

Nakao M, Ishihara Y, Kim CH, Hyun IG

OBJECTIVES: Air pollution is a growing concern in Korea because of transboundary air pollution from mainland China. A panel study was conducted to clarify the effects of air pollution on...
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Association between endotoxin levels in dust from indoor swine housing environments and the immune responses of pigs

Roque K, Shin KM, Jo JH, Lim GD, Song ES, Shin SJ, Gautam R, Lee JH, Kim YG, Cho AR, Kim CY, Kim HJ, Lee MS, Oh HG, Lee BC, Kim JH, Kim KH, Jeong HK, Kim HA, Heo Y

Indoor animal husbandry environments are inevitably contaminated with endotoxins. Endotoxin exposure is associated with various inflammatory illnesses in animals. This cross-sectional study evaluated the relationship between the degree of endotoxin...
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The Relevance of Nasal Cytology in the Workup of House Dust Mite-Induced Allergic Rhinitis

Gelardi M, Puccinelli P, Incorvaia , Passalacqua G, Ciprandi G, Italian Cometa Study Group

No abstract available.
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Efficacy and Safety of Sublingual Immunotherapy in Elderly Rhinitis Patients Sensitized to House Dust Mites

Kim JH, Lee JH, Ye YM, Lee JH, Park JW, Hur GY, Kim JH, Lee HY, Shin YS, Yang EM, Park HS

PURPOSE: This study aims to determine the efficacy and safety of house dust mite (HDM)-sublingual immunotherapy (SLIT) in elderly patients with AR. METHODS: A total of 45 patients aged ≥ 60...
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Evaluation of skin prick test to screen dust mite sensitization in chronic respiratory diseases in Southern Vietnam

Chu HT, Godin I, PhÆ°Æ¡ng N, Nguyen LH, Hiep TT, Xuan NM, Corazza F, Michel O

BACKGROUND: In the view of the epidemic growth of sensitization to indoor allergens in Southern Vietnam, there is a requirement to screen large population. OBJECTIVE: To evaluate skin prick tests (SPTs)...
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Changes in basophil activation during immunotherapy with house dust mite and mugwort in patients with allergic rhinitis

Kim SH, Kim SH, Chung SJ, Kim JH, Lee SY, Kim BK, Lim KW, Chang YS

BACKGROUND: The basophil activation test (BAT) is a promising tool for monitoring allergen-specific immunotherapy responses. OBJECTIVE: We aimed to investigate the changes in basophil activation in response to the inhalant allergens...
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A Retrospective Study of Clinical Response Predictors in Subcutaneous Allergen Immunotherapy With House Dust Mites for Allergic Rhinitis

Lee JH, Kim SC, Choi H, Jung CG, Ban GY, Shin YS, Nahm DH, Park HS, Ye YM

PURPOSE: House dust mites (HDM) are major allergens that cause allergic rhinitis (AR). Allergen-specific subcutaneous immunotherapy (SCIT) has been shown to be clinically beneficial in many clinical trials. Such trials,...
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Functional disorders of the lung and symptoms of respiratory disease associated with occupational inhalation exposure to wood dust in Iran

Neghab M, Jabari Z, Kargar Shouroki F

OBJECTIVES: The possible adverse respiratory effects of airborne pollutants in sawmills have not been thoroughly investigated in Iran. Additionally, the extent to which workers are exposed to this organic dust...
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Road dust and its effect on human health: a literature review

Khan RK, Strand MA

The purpose of this study was to determine the effects of road dust on human health. A PubMed search was used to extract references that included the words “road dust”...
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