Pediatr Gastroenterol Hepatol Nutr.  2019 Mar;22(2):193-200. 10.5223/pghn.2019.22.2.193.

Intestinal Spirochetosis: A Case Series and Review of the Literature

Affiliations
  • 1Kidz Health Castle, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium. Yvan.Vandenplas@uzbrussel.be
  • 2Department of Pathology, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.

Abstract

A clinical suspicion of intestinal spirochetosis is required when patients have long lasting complaints of abdominal pain, diarrhea, rectal bleeding, weight loss, and nausea. An endoscopy with biopsies needs to be performed to confirm the diagnosis of intestinal spirochetosis. The diagnosis of intestinal spirochetosis is based on histological appearance. Intestinal spirochetosis can also be associated with other intestinal infections and juvenile polyps (JPs). JPs seem to be more frequent in patients with intestinal spirochetosis than in patients without intestinal spirochetosis. Intestinal spirochetosis in children should be treated with antibiotics. Metronidazole is the preferred option. In this article, we describe 4 cases of intestinal spirochetosis in a pediatric population and provide a review of the literature over the last 20 years. Intestinal spirochetosis is a rare infection that can cause a variety of severe symptom. It is diagnosed based on histological appearance.

Keyword

Spirochete infections; Endoscopy; Co-infection; Polyps; Antibiotics

MeSH Terms

Abdominal Pain
Anti-Bacterial Agents
Biopsy
Child
Coinfection
Diagnosis
Diarrhea
Endoscopy
Hemorrhage
Humans
Metronidazole
Nausea
Polyps
Spirochaetales Infections
Weight Loss
Anti-Bacterial Agents
Metronidazole
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