J Korean Assoc Pediatr Surg.  1995 Dec;1(2):186-189. 10.13029/jkaps.1995.1.2.186.

Hirschsprung's Disease Associated with Neonatal Intestinal Perforation

Affiliations
  • 1Department of Surgery, University of msan College of Medicine, and Asan Medical Center, Seoul, Korea.

Abstract

Neonatal intestinal perforation is mainly caused by necrotizing enterocolitis, intestinal atresia, meconium ileus or unknown etiology. Occasionally, Hirschsprung's disease presents with neonatal intestinal perforation, of which, it is known that total colonic aganglionosis is common. Therefore, Hirschsprung's disease should be considered as a cause of neonatal intestinal perforation. The authors have experienced 3 cases of neonatal Hirschsprung's disease associated with colonic perforations. Cecal perforations were noted in 2 cases with aganglionosis from descending colon and sigmoid perforation in a case with aganglionosis in rectum. These cases will be discussed with literature review.

Keyword

Hirschsprung's disease; Intestinal perforation; Neonate

MeSH Terms

Colon
Colon, Descending
Colon, Sigmoid
Enterocolitis, Necrotizing
Hirschsprung Disease*
Humans
Ileus
Infant, Newborn
Intestinal Atresia
Intestinal Perforation*
Meconium
Rectum
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