Korean J Pediatr Infect Dis.  2002 May;9(1):95-99. 10.14776/kjpid.2002.9.1.95.

A Case of Epstein-Barr Virus-Associated Hemophagocytic Syndrome with Ascites

• Choi YN
• Jang GC
• Kim DS
• Park YN

• KMID: 2440132
• DOI: http://doi.org/10.14776/kjpid.2002.9.1.95

Abstract

Hemophagocytic syndrome(HPS) has four subgroup, sporadic disorder, associated with acute infection, familial form seen in children, and associated with malignant disorders, immunodeficiencies, defective leukocyte function. Histologically, Hemopoietic cells are actively ingested by moncytes/macrophages in various organs, including lymph nodes, bone marrow, liver, and spleen. Epstein-Barr virus(EBV) is now thought to be one of the major causes for the virus-associated hemophagocytic syndrome(VAHS). Epstein-Barr(EB) virus infection is common, with up to 90% of individuals demonstrating positive titiers by age 20. Although elevated liver function tests commonly occur, severe hepatitis is rare. Only seven cases of ascites complicating Epstein-Barr infection are reported, but none clearly demonstrate the abscence of other causes of hepatic dysfunction. We are reporting a case of Epstein-Barr Virus-associated hemophagocytic syndrome with ascites.

Keyword

Epstein-Barr viurs; Virus-associated hemophagocytic syndrome; Ascites

MeSH Terms

Ascites*
Bone Marrow
Child
Hepatitis
Humans
Leukocytes
Liver
Liver Function Tests
Lymph Nodes
Lymphohistiocytosis, Hemophagocytic*
Spleen