Clin Pediatr Hematol Oncol.
2012 Apr;19(1):49-52.
A Case of Epstein-Barr Virus Associated Hemophagocytic Lymphohistiocytosis after Scrub Typhus Infection
- Affiliations
-
- 1Department of Pediatrics, Yonsei University Wonju College of Medicine, Wonju Christian Hospital, Wonju, Korea. khm9120@yonsei.ac.kr
- 2Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju Christian Hospital, Wonju, Korea.
Abstract
- A 7-year-old boy with pancytopenia, cervical lymphadenopathy, interstitial pneumonia, and hepatosplenomegaly was diagnosed with Epstein-Barr Virus (EBV)-associated hemophagocytic lymphohistiocytosis. His clinical course was characterized by hepatorenal syndrome and myocarditis. Based on his serological markers for EBV and an immunochromatography test for scrub typhus, this case was inferred as an EBV infection that was reactivated during tsutsugamushi infection. We treated this patient with the HLH-2004 protocol and administered clarithromycin. Normal ferritin level was achieved within 8 weeks after starting chemotherapy and antibiotics.
MeSH Terms
-
Anti-Bacterial Agents
Child
Clarithromycin
Epstein-Barr Virus Infections
Ferritins
Hepatorenal Syndrome
Herpesvirus 4, Human
Humans
Immunochromatography
Lung Diseases, Interstitial
Lymphatic Diseases
Lymphohistiocytosis, Hemophagocytic
Myocarditis
Pancytopenia
Scrub Typhus
Anti-Bacterial Agents
Clarithromycin
Ferritins
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Epstein-Barr Virus Associated Hemophagocytic Syndrome after Scrub Typhus Infection
- A case of hemophagocytic lymphohistiocytosis caused by an Epstein-Barr virus infection, presenting with unremitting fever and rash
- A Case of Death Due to Hemophagocytic Lymphohistiocytosis Accompanied by Scrub Typhus
- A Case of Epstein-Barr Virus-Associated Hemophagocytic Syndrome Demonstrated by In Situ Hybridization
- A Case of Epstein-Barr Virus-Associated Hemophagocytic Syndrome with Ascites
