Korean J Clin Oncol.  2018 Dec;14(2):142-145. 10.14216/kjco.18024.

Radiation segmentectomy for gastric leiomyosarcoma hepatic metastasis

• Roh S

• KMID: 2432613
• DOI: http://doi.org/10.14216/kjco.18024

Abstract

Metastases to the liver can be found in various malignancies, most commonly originating from the colon, rectum, pancreas, stomach, esophagus, breast, lung, and melanoma. Surgical resection of liver metastasis is generally considered to be the definitive therapy fore cure. However, many patients are unable to undergo surgical resection due to medical comorbidities or multifocal extent of malignant disease affecting the liver. Among patients not eligible for surgery, other therapies exist for treatment in order to down stage the disease for surgical resection or for palliation. Radioembolization of hepatic metastases has shown to improve outcomes among patients with variety of malignancies including more common malignancies such as colorectal cancer. Yttrium-90 (Y-90) radioembolization has been successfully used in the management of hepatic metastases. A small series of metastatic sarcoma to the liver treated with radioembolization showed a promising response. We report a case of metastatic gastric leiomyosarcoma to the liver treated with Y-90 glass microspheres therapy using the radiation segmentectomy approach, previously described for hepatocellular carcinoma.

Keyword

Leiomyosarcoma; Liver; Metastasis; Neoplasm; Embolization

MeSH Terms

Breast
Carcinoma, Hepatocellular
Colon
Colorectal Neoplasms
Comorbidity
Esophagus
Glass
Humans
Leiomyosarcoma*
Liver
Lung
Mastectomy, Segmental*
Melanoma
Microspheres
Neoplasm Metastasis*
Pancreas
Rectum
Sarcoma
Stomach