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Curative liver transplantation after lung resection for advanced hepatocellular carcinoma with lung metastasis and inferior vena cava tumor thrombosis: a case report

Joo DJ, Kim DY, Seong J, Kim HJ, Lee JG, Han DH, Choi GH, Kim MS, Choi JS, Kim SI

Hepatocellular carcinoma (HCC) with distant metastasis is an absolute contraindication for liver transplantation (LT). However, it is still unclear whether LT is feasible or acceptable in such patients, albeit after...
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Rho-Kinase as a Therapeutic Target for Nonalcoholic Fatty Liver Diseases

Sousa-Lima I, Kim HJ, Jones J, Kim YB

Nonalcoholic fatty liver disease (NAFLD) is a major public health problem and the most common form of chronic liver disease, affecting 25% of the global population. Although NAFLD is closely...
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Selected deceased donor liver transplantation in controlled Fournier’s gangrene: a case report

Noh BG, Lee N, Lee BC, Yoon M

Bacterial infection represents a turning point in the natural history of cirrhosis, causing the development of acute-on-chronic liver failure. It significantly affects the outcome of patients listed for liver transplantation....
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Clinical sequence of an adult recipient undergone split liver transplantation using a right liver graft with erroneous deprivation of the middle hepatic vein trunk: a case report

Yang G, Hwang S, Ahn CS, Ha TY, Jung DH

The anatomy of middle hepatic vein (MHV) varies widely, and some individuals have aberrant MHV anatomy, thus there is risk of iatrogenic damage to graft MHV during liver splitting. We...
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Hepatic artery reconstruction using interposition of autologous saphenous vein conduit for living donor liver transplantation: a case report

Moon DB, Hwang S, Jung DH, Ahn CS, Park GC, Ha TY, Song GW, Yoon YI, Lee SG

We have preferentially used the right gastroepiploic artery (RGEA) as an alternative for the recipient hepatic artery (HA) inflow during living donor liver transplantation (LDLT), but it was not always...
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Indications and outcomes of liver transplantation for post-Kasai biliary atresia in young adults

Namgoong JM, Hwang S, Ahn CS, Moon DB, Ha TY, Song GW, Jung DH, Park GC, Yoon YI, Kim KM, Lee SG

Background: Some young adults have a long survival period with native liver after Kasai portoenterostomy (KPE) for biliary atresia (BA). However, a considerable proportion of these patients require liver transplantation...
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Efficacy and safety of a switch from twicedaily tacrolimus to once-daily generic tacrolimus in stable liver transplant patients

Kim JM, Park PJ, Hong G, Joo DJ, Kim KW, Ryu JH, Han YS, Cho JY, Song GW, Kim BW, Kim DS, Kim SH, Choi ST, You YK, Suh KS, Na YW, Kang KJ, Joh JW

Background: Once-daily tacrolimus reduces non-compliance relative to twice-daily tacrolimus. However, little is known about the safety and efficacy of conversion from twice-daily tacrolimus to generic once-daily tacrolimus in liver transplantation...
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LI-RADS version 2018 in Patients with Prior History of Hepatocellular Carcinoma: Are LR4 Observations Enough for the Diagnosis of Recurrent HCC?

Kim H, Choi JI, Kim BH, Youn SY, Kim H, Kim DH, Rha SE

Purpose: We evaluated the diagnostic performance of LI-RADS version 2018 using gadoxetic acid enhanced MRI for recurrent but untreated HCC in patients with prior history of HCC. Materials and Methods: We...
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Diagnostic Performance of Simulated Abbreviated MRI for Early-Stage Hepatocellular Carcinoma Screening: A Comparison to Conventional Dynamic Contrast-Enhanced MRI

Lim ES, Kim SM, Shin SS, Heo SH, Lee JE, Jeong YY

Purpose To compare the per-patient diagnostic performance of simulated abbreviated MRI (AMRI) to that of conventional MRI (CMRI) with full-sequence dynamic gadoxetic acid (GA) enhancement for early-stage hepatocellular carcinoma (HCC)...
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The Effect of Anticoagulant in Patients with Cirrhosis Associated with Acute Portal Vein Thrombosis

Jo HG, Kim YR, Cho EY

The treatment of portal vein thrombosis (PVT) in patients with liver cirrhosis (LC) has been controversial, and it is generally caseand institution-dependent. The occurrence of acute or extensive PVT is...
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Reappraisal of the Role of Ascitic Fluid Adenosine Deaminase for the Diagnosis of Peritoneal Tuberculosis in Cirrhosis

Dahale AS, Puri AS, Sachdeva S, Agarwal AK, Kumar A, Dalal A, Saxena PD

Background/Aims: Although peritoneal tuberculosis (TB) is one of the important differential diagnoses among cirrhotic patients with ascites, a peritoneal biopsy is not always available. High ascitic fluid adenosine deaminase (ADA)...
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Early Cardiac Dysfunction in Biopsy-proven Nonalcoholic Fatty Liver Disease

Johnson PC, Cochet AA, Gore RS, Harrison SA, Magulick JP, Aden JK, Paredes AH

Background/Aims: Nonalcoholic fatty liver disease (NAFLD) encompasses a range of diseases from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH) and has been linked to cardiovascular disease and sub-clinical cardiac...
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Diagnosis and Management of Esophageal and Gastric Variceal Bleeding: Focused on 2019 KASL Clinical Practice Guidelines for Liver Cirrhosis

Park MK, Lee YB

Varices are a frequent complication of liver cirrhosis and a major cause of mortality in patients with liver cirrhosis. Patients with decompensated cirrhosis complications have a poor prognosis and require...
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Laparoscopic management of giant hepatic hydatid cyst in a 12-year-old boy: a case report

Bairwa Bl, Singh AK, Gupta S

Hydatid disease is a zoonosis caused by a parasite, Echinococcus granulosus, characterized by a cystic lesion in the liver, lung, or (rarely) in other parts of the body. Typical radiological...
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The PNPLA3 rs738409 Variant but not MBOAT7 rs641738 is a Risk Factor for Nonalcoholic Fatty Liver Disease in Obese U.S. Children of Hispanic Ethnicity

Mansoor S, Maheshwari A, Guglielmo MD, Furuya K, Wang M, Crowgey E, Molle-Rios Z, He Z

Purpose The rs641738 C>T in membrane-bound O-acyltransferase domain-containing protein 7 (MBOAT7) is implicated, along with the rs738409 C>G polymorphism in patatin-like phospholipase domain-containing protein 3 (PNPLA3), in nonalcoholic fatty liver disease...
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Investigation of Thiol/Disulfide Balance in Obese Rats with Non-Alcoholic Fatty Liver Disease

Tursun S, Gülerman HF, Gazyağcı S, Şahin Y, Erel , Neşelioğlu S

Purpose: Due to the increasing prevalence of obesity worldwide, non-alcoholic fatty liver disease (NAFLD) has reached epidemic dimensions over time. NAFLD is the most common cause of childhood chronic liver...
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Liver transplantation for hepatocellular carcinoma with portal vein tumor thrombosis

Kim SJ, Kim JM

Traditionally, liver transplantation for hepatocellular carcinoma with portal vein tumor thrombosis is not recommended. However, with recent developments in locoregional therapies for hepatocellular carcinoma, more aggressive treatments have been attempted...
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Adjuvant oxaliplatin-based chemotherapy effect after treatment of colorectal hepatic metastasis

Kang MY, Paik JH, Ryu CG, Hwang DY

Purpose: We aimed to investigate whether adjuvant oxaliplatin-based chemotherapy after treatment for hepatic metastasis affects recurrence or survival and to determine the risk factors for recurrence or survival. Methods: Forty-six patients...
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Impact of liver cirrhosis on the clinical outcomes of patients with COVID-19: a nationwide cohort study of Korea

Jeon D, Son M, Choi J

Background/Aims: The impact of liver cirrhosis (LC) on the clinical outcomes of patients with coronavirus disease 2019 (COVID-19) remains elusive. This study evaluated the association between LC and the development...
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Differences in radiotherapy application according to regional disease characteristics of hepatocellular carcinoma

Rim CH

There are differences in opinion regarding the application of external beam radiotherapy in the treatment of hepatocellular carcinoma. Some major guidelines state that external beam radiotherapy is yet to attain...
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