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Yonsei Criteria, a Potential Linkage to Intratumoral Foxp3⁺/CD8⁺ Ratio for the Prediction of Oncologic Outcomes in Resected Left-Sided Pancreatic Cancer

Hwang HK, Lee SH, Kim HI, Kim SH, Choi J, Kang CM, Lee WJ

PURPOSE: This study sought to investigate associations among Yonsei criteria (tumor confined to the pancreas, intact fascia layer between the distal pancreas and the left adrenal gland and kidney, and...
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Impact of Skeletal Muscle Mass on Metabolic Health

Kim G, Kim JH

Skeletal muscle is regarded as an endocrine and paracrine organ. Muscle-derived secretory proteins, referred to as myokines, mediate interactions between skeletal muscle mass and other organs such as the liver,...
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Robotic enucleation of a pancreatic uncinate neuroendocrine tumor – a unique parenchyma-saving strategy for uncinate tumors

Chin KM, Goh BK

Pancreatic neuroendocrine tumors (PNET) comprise up to 10% of all pancreatic solid tumors. There has been much interest in recent years with regards to the role of limited resection and...
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Extended distal pancreatectomy with thoracic wall resection after neoadjuvant FOLFIRINOX: Is there a limit of resection for pancreatic cancer after downstaging?

Giuliani T, López Rubio M, Montalvá Oron E, Maupoey Ibañez J, Boscá Robledo A, López Valdivia C, Pérez Rojas J, Lopez Andujar R

Indications and outcomes of extended pancreatectomies have been recently appraised by the International Study Group for Pancreatic Surgery. However, no definitive conclusions have been drawn, particularly in the setting of...
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Prognostic value of COL6A3 in pancreatic adenocarcinoma

Svoronos C, Tsoulfas G, Souvatzi M, Chatzitheoklitos E

BACKGROUNDS/AIMS: Pancreatic cancer is one of the most fatal human malignancies with poor prognosis, despite advances in therapy. Here, we evaluated the potential role of collagen type VI α3 chain...
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Hepatobiliary and pancreatic surgery in the elderly: Current status

Papis D, Vagliasindi A, Maida P

Hepato-pancreatico-biliary (HPB) surgery includes major hepatic resection and pancreatic surgery, both procedures are complex and have a potentially high complication rate. The presence of centers of excellence with a high...
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A Novel Pancreatic Imaging Window for Stabilized Longitudinal In Vivo Observation of Pancreatic Islets in Murine Model

Park I, Hong S, Hwang Y, Kim P

Longitudinal imaging of murine pancreas is technically challenging due to the mechanical softness of the tissue influenced by peristalsis. Here, we report a novel pancreatic imaging window for long-term stabilized...
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Prediction of postoperative pancreatic fistula using a nomogram based on the updated definition

Guo CX, Shen YN, Zhang Q, Zhang XZ, Wang JL, Gao SL, Lou JY, Que RS, Ma T, Liang TB, Bai XL

PURPOSE: The International Study Group on Pancreatic Fistula's definition of postoperative pancreatic fistula (POPF) has recently been updated. This study aimed to identify risk factors for POPF in patients having...
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A case of IgG4-related disease associated with psoriasis-like skin rash and hypereosinophilic syndrome

Park HK, Han MH, Lee SJ

Immunoglobulin (Ig) G4-related disease (IgG4-RD) is newly recognized immune-mediated and fibroinflammatory conditions with various organ involvements. Any organs can be involved, but the pancreas, salivary gland, lymph nodes, and orbit...
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Cystic fibrosis lung disease: Current perspectives

Jung JA

Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). These mutations alter the synthesis, processing, function, or...
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Clinical usefulness of fluorodeoxyglucose-positron emission tomography/computed tomography and carbohydrate antigen 19-9 in patients with periampullary tumors

Kim JE, Shin MH, Choi NK

PURPOSE: The prognosis of periampullary cancer varies with its origin and early diagnosis influences outcome. Endoscopic ultrasound, computed tomography, fine needle aspiration, and fluorodeoxyglucose-positron emission tomography/computed tomography (¹⁸FDG-PET/CT) are helpful...
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Two Cases of Unresectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgical Resection

Huh G, Chun JW, You MS, Paik WH, Lee SH, Kim YT, Ryu JK

We report two cases of patients with unresectable pancreatic cancer treated with neoadjuvant chemotherapy and surgical resection. In the first case, main mass was located at the neck of the...
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Abdominal pain without bruising or sign of trauma: pancreatic injuries in children is difficult to predict

Bak SY, Lee HJ, Baek HS, Ahn SM, Cho GC

Pancreatic injuries due to trauma in children are rare. An early diagnosis is difficult as the signs and symptoms are insidious, but delays in diagnosis can lead to significant complications....
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Docosahexaenoic Acid Inhibits Expression of Fibrotic Mediators in Mice With Chronic Pancreatitis

Lee S, Jeong YK, Lim JW, Kim H

BACKGROUND: Chronic pancreatitis (CP) is an irreversible progressive disease that destroys exocrine parenchyma, which are replaced by fibrous tissue. As pancreatic fibrosis is a key feature of CP, reducing fibrotic...
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Progression of diabetic nephropathy after successful pancreas transplantation alone: a case report

Kim Y, Kim DI, Shim JR, Lee TB, Yang KH, Ryu JH, Lee HJ, Choi BH

Pancreas transplantation is the only method that can nearly cure insulin-dependent diabetes mellitus. However, the effect of pancreas transplantation on patients with diabetic nephropathy has recently been considered controversial. In...
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Stage 1A Pancreatic Cancer Initially Manifesting as Clinical Acute Pancreatitis

Yoo DR, Kim J, Baek SH, Lee J, Nam SH, Lee SH, Kim MH

Pancreatic cancer has a poor prognosis due to the difficulty of early diagnosis. Observation is recommended for early diagnosis of pancreatic cancer in elderly patients with risk factors such as...
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Immunohistochemical localization of nerve injury-induced protein-1 in mouse tissues

Ekanayake , Ahn M, Kim J, Choi Y, Shin T

Nerve injury-induced protein (Ninjurin)-1 is a cell adhesion molecule that is upregulated in neurons and Schwann cells after transection injury in rats. In this study, we investigated the localization of...
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Diabetes and Cancer: Cancer Should Be Screened in Routine Diabetes Assessment

Suh S, Kim KW

Cancer incidence appears to be increased in both type 1 and type 2 diabetes mellitus (DM). DM represents a risk factor for cancer, particularly hepatocellular, hepatobiliary, pancreas, breast, ovarian, endometrial,...
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Laparoscopic Whipple's Operation for Locally Advanced Gastric Cancer Invading the Pancreas and Duodenum: a Case Report

Lee CM, Yoon SY, Park S, Park SH

Few surgeons have adopted pancreaticoduodenectomy (PD) for the treatment of advanced gastric cancer (AGC) invading the pancreas or duodenum because it remains controversial whether its prognostic benefits outweigh the high...
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Correlation of Clinical and Histopathologic Parameters with Ultrasonographic Grades in Pediatric Non-Alcoholic Fatty Liver Disease

Kang BK, Kim M, Shin SJ, Kim YJ

BACKGROUND: Liver biopsy is the gold standard for diagnosing non-alcoholic steatohepatitis (NASH), but liver biopsy in children is not available in many institutes and many parents are reluctant to agree...
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