J Korean Soc Radiol.  2018 Jun;78(6):422-425. 10.3348/jksr.2018.78.6.422.

Small Cell Carcinoma of the Ovary Hypercalcemic Type: A Case Report

• Nam YK
• Kim SH
• Choi MS

• KMID: 2412362
• DOI: http://doi.org/10.3348/jksr.2018.78.6.422

Abstract

Small cell carcinoma of the ovary, hypercalcemic type is a rare ovarian tumor. This tumor has three distinctive clinical features: i) an occurrence in young women, ii) the presence of hypercalcemia in 62% of cases, and iii) a high degree of malignancy. The radiologic findings of the tumors are usually large and a predominantly solid mass with internal necrosis, hemorrhage and cystic degeneration. We report on the CT and MRI findings of an ovarian small cell carcinoma, hypercalcemic type in a 17-year-old female who presented 1 month abdominal discomfort with weight loss.

MeSH Terms

Adolescent
Carcinoma, Small Cell*
Female
Hemorrhage
Humans
Hypercalcemia
Magnetic Resonance Imaging
Necrosis
Ovarian Neoplasms
Ovary*
Weight Loss

Figure

• 

  Fig. 1. A 17-year-old female with ovarian masses detected on the CT scan. A. This contrast enhanced CT scan of the ovarian small cell carcinoma shows an approximately 15 cm sized heterogeneous mass in the pelvic cavity. B. The axial T2-weighted MR image shows a multiseptated mass with an increased signal intensity, suggesting an internal cystic change or necrosis. C. The axial T1-weighted MR image shows a heterogeneous low signal intensity mass. D. The axial T1-weighted contrast enhanced MR image shows a peripheral solid portion with enhancement. E. Gross picture of the ovarian small cell carcinoma shows a pale, white to gray solid mass with foci of cystic change, hemorrhage, and necrosis. F. The tumor cells are relatively monotonous and show scanty cytoplasm (hematoxylin and eosin stain, × 400).

Reference

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