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Real-world Treatment Pattern and Outcomes of Hypercalcemia among Solid Tumor Patients

Shin DE, Park SH, Kim SH, Suh SY, Jo YH, Cho YS, Im SA, Lee JY

BACKGROUND: Hypercalcemia is an important metabolic emergency condition in cancer patients. Bisphosphonate is the treatment of choice for hypercalcemia, whereas calcitonin and hydration with furosemide are recommended for acute supportive...
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Primary hyperparathyroidism versus familial hypocalciuric hypercalcemia: a challenging diagnostic evaluation in an adolescent female

Tosur M, Lopez ME, Paul DL

Primary hyperparathyroidism (PHPT) and familial hypocalciuric hypercalcemia (FHH) have significantly different treatment approaches, so physicians must be careful to differentiate these 2 diseases. Herein, we report a 14-year-old female who...
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A Case of Hypercalcemia and Antibiotic-Related Acute Kidney Injury Following Implantation of Antibiotic Impregnated Calcium Sulfate Beads

Challener , Abu Saleh

No abstract available.
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Polymeric Nanoparticles Containing Both Antigen and Vitamin D₃ Induce Antigen-Specific Immune Suppression

Jung HH, Kim SH, Moon JH, Jeong SU, Jang S, Park CS, Lee CK

The active form of vitamin D3, 1,25-dihydroxyvitamin D₃ (aVD₃), is known to exert beneficial effects in the treatment of autoimmune diseases because of its immunosuppressive effects. However, clinical application of...
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Infantile hypercalcemia with novel compound heterozygous mutation in SLC34A1 encoding renal sodium-phosphate cotransporter 2a: a case report

Kang SJ, Lee R, Kim HS

Idiopathic infantile hypercalcemia is characterized by hypercalcemia, dehydration, vomiting, and failure to thrive, and it is due to mutations in 24-hydroxylase (CYP24A1). Recently, mutations in sodium-phosphate cotransporter (SLC34A1) expressed in...
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Intrathyroidal Parathyroid Carcinoma in Chronic Kidney Disease: A Case Report and Review of Literature

Kim MK, Song CM, Tae K, Ji YB

When parathyroid carcinoma occurs in the thyroid gland, it is very difficult to diagnose before surgery because imaging studies and aspiration cytology cannot distinguish parathyroid carcinoma from thyroid nodule or...
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Ectopic Mediastinal Parathyroid Adenoma in a Patient with Chronic Kidney Disease: A Case Report

Choo DM, Kim JH, Kim SS

We report an ectopic mediastinal parathyroid adenoma in a patient with chronic kidney disease who presented with refractory hypercalcemia. Technetium-99m-sestamibi scintigraphy is a valuable imaging technique for the detection of...
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The Development and Application of a New Problem Based Learning Module for Students in an Advanced Practice Nurse Program for Oncology

Kim HJ, Kim JH, Park JY, Park JS, Park EY

PURPOSE: The purposes of this study were to develop a problem based learning (PBL) module for cancer symptom management and oncology emergencies, and to evaluate the module after applying it...
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Combined Hepatocellular Carcinoma and Neuroendocrine Carcinoma with Ectopic Secretion of Parathyroid Hormone: A Case Report and Review of the Literature

Kwon HJ, Kim JW, Kim H, Choi Y, Ahn S

Primary combined hepatocellular carcinoma (HCC) and neuroendocrine carcinoma is a rare entity, and so is hypercalcemia due to ectopic parathyroid hormone (PTH) secretion by tumor. A 44-year-old man with hepatitis...
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Small Cell Carcinoma of the Ovary Hypercalcemic Type: A Case Report

Nam YK, Kim SH, Choi MS

Small cell carcinoma of the ovary, hypercalcemic type is a rare ovarian tumor. This tumor has three distinctive clinical features: i) an occurrence in young women, ii) the presence of...
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Effects of Serum Albumin, Calcium Levels, Cancer Stage and Performance Status on Weight Loss in Parathyroid Hormone-Related Peptide Positive or Negative Patients with Cancer

Lee JY, Hong N, Kim HR, Lee BW, Kang ES, Cha BS, Lee YH

BACKGROUND: A recent animal study showed that parathyroid hormone-related peptide (PTHrP) is associated with cancer cachexia by promoting adipose tissue browning, and we previously demonstrated that PTHrP predicts weight loss...
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Subcutaneous Fat Necrosis of the Newborn: A Case Report

Kim SH

Subcutaneous fat necrosis (SFN) in newborns is a rare disease that affects infants in the first few weeks after birth. The lesion involves the back, buttocks, thighs, arms, and cheeks...
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A case of bisphosphonate-related osteonecrosis of the jaw with a particularly unfavourable course: a case report

Viviano M, Addamo A, Cocca S

Bisphosphonates are drugs used to treat osteoclast-mediated bone resorption, including osteoporosis, Paget disease, multiple myeloma, cancer-related osteolysis, and malignant hypercalcemia. The use of these drugs has increased in recent years...
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Williams Syndrome with Multiple Cervical Vertebral Fusion Presenting Dysphagia: A Case Report

Jang BH, Hwang CH

Williams syndrome is a multiple-system disorder, caused by deletion of the locus 7q11-23 gene and characterized by an ‘elfin’ facial appearance, developmental delay, cardiovascular disorders, and transient hypercalcemia. Vertebral abnormalities...
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Clinicopathological characteristics of extremely young Korean multiple myeloma patients: therapeutic implications

Shin J, Koh Y, Youk J, Kim M, Kim BS, Choi CW, Sung HJ, Park Y, Yoon SS, Kim I

BACKGROUND/AIMS: Although multiple myeloma (MM) is typically a disease of the elderly, a certain subset of extremely young patients exists. It is necessary to establish clinicopathological characteristics for this population. METHODS:...
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Hypercalcemia in a Patient with Systemic Lupus Erythematosus

Lee JM, Kwack DH, Yoon CH, Choi B, Kim YO, Kim YS, Yoon SA

Hypercalcemia is a common clinical problem. The most frequent causes of hypercalcemia include primary hyperparathyroidism and malignancy; systemic lupus erythematosus (SLE) is a very rare cause of hypercalcemia. Here we...
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Successful Radiofrequency Ablation of Parathyroid Adenoma in an Older Patient with Primary Hyperparathyroidism

Soh MS, Lee SH, Choi YJ, Kim HJ, Kim DJ, Lee KW, Han SJ

Primary hyperparathyroidism is one of the most common endocrine diseases and is defined as the inappropriate overproduction of parathyroid hormone, resulting in hypercalcemia. It occurs mostly as a result of...
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A Case of Severe Hypercalcemia Causing Acute Kidney Injury: An Unusual Presentation of Acute Lymphoblastic Leukemia

Hyun HS, Park PG, Kim JC, Hong KT, Kang HJ, Park KD, Shin HY, Kang HG, Ha IS, Cheong HI

Severe hypercalcemia is rarely encountered in children, even though serum calcium concentrations above 15-16 mg/dL could be life-threatening. We present a patient having severe hypercalcemia and azotemia. A 14-year-old boy...
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A Diagnosis to Consider in an Adult Patient with Facial Features and Intellectual Disability: Williams Syndrome

DoÄŸan OA, ÅžimÅŸek Kiper PO, Utine GE, AlikaÅŸifoÄŸlu M, BoduroÄŸlu K

Williams syndrome (OMIM #194050) is a rare, well-recognized, multisystemic genetic condition affecting approximately 1/7,500 individuals. There are no marked regional differences in the incidence of Williams syndrome. The syndrome is...
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Hypercalcemia, multiple osteolytic lesions, and acute renal failure: a rare presentation of B-cell acute lymphoblastic leukemia

Puri V, Sharma P, Gopalakrishnan S, Sikka M, Avasthi R

No abstract available.
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