J Korean Orthop Assoc.  2003 Aug;38(4):355-360.

Age-related Morphologic and Pathologic Features of Acetabular Labrum in the Adult Hip

• Hwang DS
• Lee WS
• Kim YM
• Nam DC
• Kang C

Abstract

PURPOSE
We evaluated the morphohistologic features of acetabular labral tear to confirm the cause of age-related hip pain in the adulthip. MATERIALS AND METHODS: Sixty-two acetabular labrums were examined during hemiarthroplasty for hip fracture. We recorded the incidence, location, degree and morphology of the labral lesion. Twenty-five torn labrum specimens were stained with Hematoxylin and Eosin (H&E) and protein S-100 and Factor VIII antigen were examined immunohistochemically. RESULTS: Among 53 cases with labral lesions, 88% of the hips (47 cases) were in patients older than 60 years, and 86.8% of the lesions were located in the anterior quadrant of the acetabulum. Torn labrums showed mainly degenerative change with collagen separation and myxoid change by H&E staining. Nerve fibers and nerve endings were rarely observed in the labral substance but were frequently observed in the adjacent synovium by immunohistochemistry for S-100. Microvessels were increased around labral lesions but did notinvade into the deep labral substance at torn labrums in Factor VIII antigen staining. CONCLUSION: Acetabular labral lesion was common in the aging hip. Hip pain due to a labral lesion may be associated with inflammationof the adjacent synovium due to mechanical irritation.

Keyword

Age-related adult hip; Acetabular labral lesions; Morphologic and pathologic features

MeSH Terms

Acetabulum*
Adult*
Aging
Collagen
Eosine Yellowish-(YS)
Factor VIII
Hematoxylin
Hemiarthroplasty
Hip*
Humans
Immunohistochemistry
Incidence
Microvessels
Nerve Endings
Nerve Fibers
Synovial Membrane
Collagen
Eosine Yellowish-(YS)
Factor VIII
Hematoxylin