Brain Tumor Res Treat.  2017 Apr;5(1):34-36. 10.14791/btrt.2017.5.1.34.

Toxoplasmic Encephalitis in Patient with Acquired Immunodeficiency Syndrome

• Lee SB
• Lee TG

• KMID: 2378303
• DOI: http://doi.org/10.14791/btrt.2017.5.1.34

Abstract

Toxoplasmic encephalitis (TE) is an opportunistic infection found in immunocompromised patients and TE related cerebral mass lesion is often reported in acquired immunodeficiency acquired immunodeficiency syndrome (AIDS) patients. However, incidence of TE related AIDS in Korea is still rare and is unfamiliar to neurosurgeons. Differential diagnosis is needed to rule out other brain lesions. A 39-year-old man visited the emergency room with rapid progressive left hemiparesis. Magnetic resonance imaging showed a ring-enhanced mass lesion in his right frontal lobe. Human immunodeficiency virus and Toxoplasma gondii immunoglobulin G were tested positive by a serologic test. We report here a rare case of patient with TE related AIDS.

Keyword

Acquired immunodeficiency syndrome; Encephalitis; Toxoplasmosis

MeSH Terms

Acquired Immunodeficiency Syndrome*
Adult
Brain
Diagnosis, Differential
Emergency Service, Hospital
Encephalitis*
Frontal Lobe
HIV
Humans
Immunocompromised Host
Immunoglobulin G
Incidence
Korea
Magnetic Resonance Imaging
Neurosurgeons
Opportunistic Infections
Paresis
Serologic Tests
Toxoplasma
Toxoplasmosis
Immunoglobulin G

Figure

• 

  Fig. 1 MRI showing a ring-enhanced mass with mild edema in the right frontal lobe.

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  Fig. 2 Many minute, basophilic bradyzoites fill a ruptured protozoal pseudocyst with surrounding brain tissue which shows edema and infiltrating inflammatory cells (hematoxylin-eosin stain, ×200).

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  Fig. 3 Contrast enhanced T1-weighted image after brain biopsy shows multiple ring enhancement lesions with severe edema throughout the brain.

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