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A case of toxic epidermal necrolysis induced by cytomegalovirus infection followed by DRESS (drug reaction with eosinophilia and systemic symptoms)

Sim DW, Son S, Yu J, Koh YI

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions. Although viral reactivation is associated with DRESS syndrome, its role in...
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Anti-PP₁P(k) (Tj(a)) Antibody in a Korean Female Patient with p Phenotype Confirmed by Genotyping

Kim B, Choi SJ, Cho D, Kim S, Kim HO

In this study, we report a case of anti-PP₁P(k) (Tj(a)) alloantibody with p phenotype detected and confirmed in a 20-year-old Korean woman diagnosed with anemia during long-term rehabilitation treatment due...
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Investigation of a Mumps Outbreak in a Dental Clinic at a University Hospital

Lee JE, Lee SO, Kang JS, Yi J, Kim KH

BACKGROUND: The Korean Society of Infectious Diseases recommends non-mandatory vaccination of newly employed healthcare workers (HCWs) with 2 measles–mumps–rubella (MMR) vaccine doses. Here, we aimed to investigate the seroprevalence of...
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Detection of Human Anti-Trypanosoma cruzi Antibody with Recombinant Fragmented Ribosomal P Protein

Kim YH, Yang Z, Lee J, Ahn HJ, Chong CK, Maricondi , Dias RF, Nam HW

Chagas disease is caused by the protozoan parasite Trypanosoma cruzi, and is endemic in many Latin American countries. Diagnosis is based on serologic testing and the WHO recommends two or...
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Frosted Branch Angiitis Associated with Epstein-Barr Virus Infection

Son HW, Lee JE

PURPOSE: To report a case of frosted branch angiitis (FBA) associated with Epstein-Barr virus (EBV) infection in a child. CASE SUMMARY: A 7-year-old boy presented with bilateral blurred vision. On ophthalmic...
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Herpetic Esophagitis in Immunocompetent Child

Altamimi E, Alorjani M, Alquran WY

A previously healthy 2.5-year-old male child presented with vomiting, diarrhea, and fever. During hospitalization he developed odynophagia and refusal to eat. His symptoms did not respond to acid suppressant therapy....
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Weak D type 33 Found in a Patient with a Weak D Phenotype: The First Case in Korea

Yu H, Park JE, Park G, Cho D

RHD genotyping is a useful adjunct to serologic testing. Although the use of RHD genotyping in the detection of Asia type DEL in serological D negative Koreans is gradually increasing,...
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Advances in Serological Diagnosis of Taenia solium Neurocysticercosis in Korea

Ahn CS, Kim JG, Huh S, Kang I, Kong Y

Cysticercosis, a parasitic disease caused by Taenia solium metacestode (TsM), has a major global public health impact in terms of disability-adjusted life years. The parasite preferentially infects subcutaneous tissue, but...
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Hepatitis A Virus Infection from a Contaminated Tap of Ground Water Facility in a Neighborhood Park, Republic of Korea

Ryu S, Won SA, Uh J, Song JY

A patient with Hepatitis A virus (HAV) infection was notified to the public health authority. The identical HAV was found at a water dispensing outlet at the ground water facility...
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Infectious Diseases of the Upper Gastrointestinal Tract

Roh M, Min YW

Infectious diseases of the upper gastrointestinal tract are rare, but certain bacteria including Treponema pallidum and Mycobacterium tuberculosis may infect the esophagus, stomach, and duodenum even in an immunocompetent individual....
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Multi-Epitope Fusion Protein Eg mefAg-1 as a Serodiagnostic Candidate for Cystic Echinococcosis in Sheep

Tianli L, Xifeng W, Zhenzhong , Lixia W, Xingxing Z, Jun Q, Qingling M, Shasha G, Ying C, Xuepeng C

Cystic echinococcosis (CE) in sheep is a hazardous zoonotic parasitic disease that is caused by Echinococcus granulosus (Eg). At present, serological test is an important diagnostic method for Eg infection...
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Recurrent Optic Neuritis and Acute Encephalopathy with Myelin Oligodendrocyte Glycoprotein Antibodies in a Korean Child

Hwang JE, Kim SH, Park S

Myelin oligodendrocyte glycoprotein (MOG) antibody-associated diseases are reported to have distinct pathogenic mechanisms, clinical courses, and therapeutic implications in comparison to other acquired demyelinating syndromes. Here, we report the case...
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Clinical Characteristics of Infectious Mononucleosis: A Retrospective Study

Kim KH, Kang HJ, Lee SJ, Song CM, Ji YB, Tae K

BACKGROUND AND OBJECTIVES: Infectious mononucleosis is mainly caused by Epstein-Barr virus infection and it presents sore throat, fever, tonsillar enlargement with exudate, cervical lymphadenopathy, hepatosplenomegaly, and etc. Therefore, it is...
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Serologic Survey and Risk Factors for Coxiella burnetii Infection among Dairy Cattle Farmers in Korea

Park JH, Chu H, Yoo SJ, Hwang KJ, Lim HS

BACKGROUND: The zoonotic disease Q fever is caused by Coxiella burnetii and usually affects high-risk human populations. We conducted a serological survey of dairy cattle farmers in Korea to determine...
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S100ß, Matrix Metalloproteinase-9, D-dimer, and Heat Shock Protein 70 Are Serologic Biomarkers of Acute Cerebral Infarction in a Mouse Model of Transient MCA Occlusion

Choi JI, Ha SK, Lim DJ, Kim SD, Kim SH

OBJECTIVE: Diagnosing acute cerebral infarction is crucial in determining prognosis of stroke patients. Although many serologic tests for prompt diagnosis are available, the clinical application of serologic tests is currently...
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Use of serology and polymerase chain reaction to detect atypical respiratory pathogens during acute exacerbation of chronic obstructive pulmonary disease

Jung CY, Choe YH, Lee SY, Kim WJ, Lee JD, Ra SW, Choi EG, Lee JS, Park MJ, Na JO

BACKGROUND/AIMS: To use serological and multiplex polymerase chain reaction (PCR) assays to examine sputum samples from patients experiencing acute exacerbation of chronic obstructive pulmonary disease (AECOPD) for the presence of...
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-D-/-D- Phenotype Frequency among Korean Donors

Lee MK, Jung SY, Kim JU, Kim JP, Kim DH, Park JR

BACKGROUND: To improve Rh-related antigen negative blood supply effectively, the Korean Red Cross (KRC) blood centers have performed Rh phenotype screening tests of C, c, E and e antigens for...
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Cytokine Profile and Immunoglobulin E-mediated Serological Food Hypersensitivity in Patients With Irritable Bowel Syndrome With Diarrhea

Katsumata , Ishii M, Lee S, Handa Y, Murao T, Fujita M, Matsumoto , Otsuki T, Shiotani A

  • KMID: 2417386
  • J Neurogastroenterol Motil.
  • 2018 Jul;24(3):415-421.
  • doi: 10.5056/jnm17114
BACKGROUND/AIMS: Food interaction, including food hypersensitivity, plays a key role in the pathogenesis of irritable bowel syndrome with diarrhea (IBS-D). Since only a few studies have been reported about the...
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Treatment of Bilateral Tonic Pupil Associated with Syphilis

Mun YS, Yang HK, Hwang JM

PURPOSE: We report a case of a male with bilateral tonic pupils associated with syphilis, that partially improved after syphilis treatment. CASE SUMMARY: A 27-year-old male presented with a 2-month history...
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Comparison of Auto RPR Plus and Auto TPIM Plus with Mediace RPR and Abbott Syphilis TP for Serologic Diagnosis of Syphilis

Kim HJ, Nah EH, Cho S, Jeong SY

BACKGROUND: Serologic testing is considered a standard method for syphilis diagnosis. We compared Auto RPR Plus and Auto TPIM Plus with previously developed assays. METHODS: The precision around the cut-off, linearity,...
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