Kidney Res Clin Pract.  2016 Dec;35(4):252-254. 10.1016/j.krcp.2016.05.003.

Acute interstitial nephritis induced by Solanum nigrum

Affiliations
  • 1Nephrology Division, Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea. inogood@catholic.ac.kr
  • 2Department of Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Abstract

Acute interstitial nephritis (AIN) is an important cause of reversible acute kidney injury and pathologically characterized by inflammatory infiltrate in the renal interstitium. Solanum nigrum (S. nigrum) is a medicinal plant member of the Solanaceae family. Although S. nigrum has been traditionally used to treat various ailments such as pain, inflammation, and fever, it has also been reported to have a toxic effect, resulting in anticholinergic symptoms. However, there have been no reports of AIN caused by S. nigrum. Here, we report the first case of biopsy-confirmed AIN after ingestion of S. nigrum. The patient was successfully treated using corticosteroid therapy.

Keyword

Acute interstitial nephritis; Corticosteroid; Solanum

MeSH Terms

Acute Kidney Injury
Eating
Fever
Humans
Inflammation
Nephritis, Interstitial*
Plants, Medicinal
Solanaceae
Solanum nigrum*
Solanum*
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