- Natural Products as Sources of Novel Drug Candidates for the Pharmacological Management of Osteoarthritis: A Narrative Review
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Kang YH, Lee HJ, Lee CJ, Park JS
- KMID: 2462877
- Biomol Ther.
- 2019 Nov;27(6):503-513.
- doi: 10.4062/biomolther.2019.139
Osteoarthritis is a chronic degenerative articular disorder. Formation of bone spurs, synovial inflammation, loss of cartilage, and underlying bone restructuring have been reported to be the main pathologic characteristics of... -
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- Changes in the constituents and UV-photoprotective activity of Astragalus membranaceus caused by roasting
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Park JY, Lee JY, Kim HD, Jang GY, Seo KH
- KMID: 2461455
- J Nutr Health.
- 2019 Oct;52(5):413-421.
- doi: 10.4163/jnh.2019.52.5.413
PURPOSE: Astragalus membranaceus (AM) is an important traditional medicinal herb. Pharmacological research has indicated that AM has various physiological activities such as antioxidant, anti-inflammatory, immunoregulatory, anticancer, hypolipidemic, antihyperglycemic, and hepatoprotective... -
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- Bioactive Compound Produced by Endophytic Fungi Isolated From Pelargonium sidoides Against Selected Bacteria of Clinical Importance
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Manganyi M, Tchatchouang CDK, Regnier T, Bezuidenhout CC, Ateba CN
- KMID: 2470145
- Mycobiology.
- 2019 Sep;47(3):335-339.
- doi: 10.1080/12298093.2019.1631121
Endophytic fungi have the ability to live inside the host plant tissues without causing neither symptoms of diseases/or harm. Opportunistic infections are accountable for majority of the outbreaks, thereby putting... -
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- Phytochemical Constituents of the Root Bark from Morus alba and Their Il-6 Inhibitory Activity
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Chang YS, Jin HG, Lee H, Lee DS, Woo ER
- KMID: 2459971
- Nat Prod Sci.
- 2019 Sep;25(3):268-274.
- doi: 10.20307/nps.2019.25.3.268
Morus alba L., known as white mulberry, is a medicinal plant belongs to family Moraceae. It has long been used commonly in Ayurvedic for the treatment of lung-heat, cough, asthma,... -
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- Improvement in histology, enzymatic activity, and redox state of the liver following administration of Cinnamomum zeylanicum bark oil in rats with established hepatotoxicity
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Niknezhad , Sayad-Fathi S, Karimzadeh A, Ghorbani-Anarkooli M, Yousefbeyk F, Nasiri E
- KMID: 2459546
- Anat Cell Biol.
- 2019 Sep;52(3):302-311.
- doi: 10.5115/acb.18.180
Formaldehyde (FA) is an environmentally-available pollutant. Since the liver acts as a detoxifier in the human body, it is the first and most affected organ in individuals exposed to higher-than-normal... -
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- Acanthamoeba in Southeast Asia – Overview and Challenges
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Bunsuwansakul C, Mahboob T, Hounkong K, Laohaprapanon S, Chitapornpan S, Jawjit S, Yasiri A, Barusrux S, Bunluepuech K, Sawangjaroen N, Salibay CC, Kaewjai C, de Lourdes Pereira M, Nissapatorn V
- KMID: 2459472
- Korean J Parasitol.
- 2019 Aug;57(4):341-357.
- doi: 10.3347/kjp.2019.57.4.341
Acanthamoeba, one of free-living amoebae (FLA), remains a high risk of direct contact with this protozoan parasite which is ubiquitous in nature and man-made environment. This pathogenic FLA can cause... -
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- Enhanced Antioxidant and Anticancer Properties of Processed Eucommiae Cortex
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Yoon HJ, Park SH, Lee HJ
- KMID: 2452784
- Nat Prod Sci.
- 2019 Jun;25(2):143-149.
- doi: 10.20307/nps.2019.25.2.143
Eucommiae Cortex (EC), bark of Eucommia ulmoides, has been known as a traditional medicine to regulate hypertension and immune system. Because silk of gum in the EC blocks the release... -
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- Essential Oil of Marrubium vulgare: Chemical Composition and Biological Activities. A Review
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Yabrir B
- KMID: 2452776
- Nat Prod Sci.
- 2019 Jun;25(2):81-91.
- doi: 10.20307/nps.2019.25.2.81
Marrubium vulgare, plant species belonging to Marrubium genus, is widespread in the Mediterranean areas, introduced elsewhere and also cultivated in many countries. Its oil is recognized to possess a considerable... -
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- Anti-oxidant and anti-adipocyte differentiation of Aster glehni and Aster yomena
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Lee JY, Park JY, Kim HD, Lee SE, Lee JH, Lee Y, Seo KH
- KMID: 2450422
- J Nutr Health.
- 2019 Jun;52(3):250-257.
- doi: 10.4163/jnh.2019.52.3.250
PURPOSE: Aster glehnii (AG) and Aster yomena (AY) are medicinal plants that belong to the family Compositea and grow widely in Korea. Plants in the genus Aster have been used... -
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- Medicinal Herbs Effective Against Atherosclerosis: Classification According to Mechanism of Action
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Kim JY, Shim SH
- KMID: 2447852
- Biomol Ther.
- 2019 May;27(3):254-264.
- doi: 10.4062/biomolther.2018.231
Atherosclerosis is a widespread and chronic progressive arterial disease that has been regarded as one of the major causes of death worldwide. It is caused by the deposition of cholesterol,... -
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- Anti-inflammatory effects of fruit and leaf extracts of Lycium barbarum in lipopolysaccharide-stimulated RAW264.7 cells and animal model
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Bae SM, Kim JE, Bae EY, Kim KA, Ly SY
- KMID: 2444936
- J Nutr Health.
- 2019 Apr;52(2):129-138.
- doi: 10.4163/jnh.2019.52.2.129
PURPOSE: Medicinal herbs have recently attracted attention as health beneficial foods and source materials for drug development. Recent studies have demonstrated that extracts of Lycium's fruits and roots have a... -
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- Foeniculum vulgare as Valuable Plant in Management of Women's Health
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Mahboubi M
- KMID: 2443622
- J Menopausal Med.
- 2019 Apr;25(1):1-14.
- doi: 10.6118/jmm.2019.25.1.1
This review paper evaluates use of Foeniculum vulgare extracts as a popular female plant in management of different ailments of women. Information in this paper was gathered from accessible sources... -
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- Hematopoiesis Activity of Sambucus javanica on Chloramphenicol-induced Aplastic Anemia Mouse Model
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Putra WE, Rifa'i M
- KMID: 2443105
- Nat Prod Sci.
- 2019 Mar;25(1):59-63.
- doi: 10.20307/nps.2019.25.1.59
Hematopoiesis has a pivotal role in the maintenance of body homeostasis. Ironically, several hematological disorder caused by chemicals, drugs, and other environmental factors lead to severe bone marrow failure. Current... -
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- Chemical Constituents of Bark of Beilschmiedia kunstleri Gamble with Anticancer, Anti-Streptococcus pyogenes, Anti-Bacillus cereus and Anti Plesiomonas shigelloides Activities
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Mollataghi A
- KMID: 2443097
- Nat Prod Sci.
- 2019 Mar;25(1):11-15.
- doi: 10.20307/nps.2019.25.1.11
Lauraceae is a family medicinal plant whose tubers possesses antimicrobial, and cytotoxic, such as antiparasitic and anti-inflammatory special effects and has been used for the medicine in the cure of... -
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- Cis-3-O-p-hydroxycinnamoyl Ursolic Acid Induced ROS-Dependent p53-Mediated Mitochondrial Apoptosis in Oral Cancer Cells
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Wang CY, Lin CS, Hua CH, Jou YJ, Liao CR, Chang YS, Wan L, Huang SH, Hour MJ, Lin CW
- KMID: 2432067
- Biomol Ther.
- 2019 Jan;27(1):54-62.
- doi: 10.4062/biomolther.2017.237
Cis-3-O-p-hydroxycinnamoyl ursolic acid (HCUA), a triterpenoid compound, was purified from Elaeagnus oldhamii Maxim. This traditional medicinal plant has been used for treating rheumatoid arthritis and lung disorders as well as... -
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- Bacopa monnieri extract improves novel object recognition, cell proliferation, neuroblast differentiation, brain-derived neurotrophic factor, and phosphorylation of cAMP response element-binding protein in the dentate gyrus
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Kwon HJ, Jung HY, Hahn KR, Kim W, Kim JW, Yoo DY, Yoon YS, Hwang IK, Kim DW
- KMID: 2459301
- Lab Anim Res.
- 2018 Dec;34(4):239-247.
- doi: 10.5625/lar.2018.34.4.239
Bacopa monnieri is a medicinal plant with a long history of use in Ayurveda, especially in the treatment of poor memory and cognitive deficits. In the present study, we hypothesized... -
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- RNA-Seq De Novo Assembly and Differential Transcriptome Analysis of Korean Medicinal Herb Cirsium japonicum var. spinossimum
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Roy NS, Kim JA, Choi AY, Ban YW, Park NI, Park KC, Yang HS, Choi IY, Kim S
- KMID: 2439224
- Genomics Inform.
- 2018 Dec;16(4):e34.
- doi: 10.5808/GI.2018.16.4.e34
Cirsium japonicum belongs to the Asteraceae or Compositae family and is a medicinal plant in Asia that has a variety of effects, including tumour inhibition, improved immunity with flavones, and... -
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- Siegesbeckia Orientalis L. Extract Attenuates Postoperative Cognitive Dysfunction, Systemic Inflammation, and Neuroinflammation
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Chu JM, Xiong W, Linghu KG, Liu Y, Zhang Y, Zhao GD, Irwin MG, Wong GT, Yu H
- KMID: 2430112
- Exp Neurobiol.
- 2018 Dec;27(6):564-573.
- doi: 10.5607/en.2018.27.6.564
A proportion of patients experience acute or even prolonged cognitive impairment after surgery, a condition known as postoperative cognitive dysfunction (POCD). It is characterized by impairment in different cognitive domains... -
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- Anti-influenza properties of herbal extract of Althaea rosea in mice
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Kim MS, Chathuranga K, Kim H, Lee JS, Kim CJ
- KMID: 2437687
- Korean J Vet Res.
- 2018 Sep;58(3):153-158.
- doi: 10.14405/kjvr.2018.58.3.153
Althaea rosea has been used in traditional Chinese medicine to treat numerous diseases, but no studies have investigated its anti-influenza properties to date. In this study, we investigated the anti-influenza... -
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- α-Isocubebene modulates vascular tone by inhibiting myosin light chain phosphorylation in murine thoracic aorta
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Ye BH, Kim EJ, Baek SE, Choi YW, Park SY, Kim CD
- KMID: 2414268
- Korean J Physiol Pharmacol.
- 2018 Jul;22(4):437-445.
- doi: 10.4196/kjpp.2018.22.4.437
α-Iso-cubebene (ICB) is a dibenzocyclooctadiene lignin contained in Schisandra chinensis (SC), a well-known medicinal herb that ameliorates cardiovascular symptoms, but the mechanism responsible for this activity has not been determined.... -
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