Ann Dermatol.
1995 Jul;7(3):222-226. 10.5021/ad.1995.7.3.222.
UVA Blocking Effect of Epidermal Melanin in Patients with Vitiligo
- KMID: 2361374
- DOI: http://doi.org/10.5021/ad.1995.7.3.222
Abstract
- BACKGROUND
Ultraviolet light induces sunburn, aging of the skin, disorders of pigment and even promotes skin cancers. Melanin is known to have a protecting role in the skin by blocking ultraviolet light.
OBJECTIVE
The purpose of this study was to evaluate UVA blocking effect of epidermal melanin and to compare UVA blocking effect among different anatomical sites.
METHODS
From 20 vitiligo patients who had undergone an epidermal graft, we obtained epidermis of normal and vitiliginous skin and measured transmitted UVA energy density.
RESULTS
The vitiliginous epidermis, devoid of melanin, blocked lower amount of UVA energy than the normal epidermis. 11.6% of irradiated UVA energy was blocked by epidermal melanin. No significant differences were observed in UVA blocking effect among different anatomical sites in normal and vitiliginous epidermis.
CONCLUSION
Epidermal melanin has some UVA blocking effect. No significant differences were found in UVA blocking effect among different anatomical sites despite the differences in the density of melanin pigment among different sites of the body.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- The effects of UVA and UVB on proliferation and melanization in SK 23 melanoma cell lines
- The Effects of PUVA on the Morphologic Changes , Proliferation of Cultured Human Keratinocytes , and on the Proliferation , Melanization and Dendricity of Cultured Human Melanocytes
- The Study on the Effects of Psoralen Derivatives on Epidermal Melanocytes in C57 BL Mice after Topical Photochemotherapy
- The Effects of Tacrolimus on Keratinocytes and Melanocytes of Vitiligo
- The Effect of High Dose UVA - 1 and UVA - 2 Irradiation on the Expression of Surface Markers of Epidermal Langerhans Cells and Induction of contact Hypersensitivity in Mice Skin
