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Deeper Wrinkle Formation and Less Melanin Production in Aged Korean Women with B Blood Type

Oh JH, Oh IG, Park CH, Shin MK, Lee SR, Lee DH, Choi M, Jin SP, Yoon HS, Cho S, Chung JH

No abstract available.
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The effects of green tea (Camellia sinensis) flower extracton melanin synthesis in B16-F10 melanoma cells

Dissanayake CY, Moon HH, Yang KM, Lee Y, Han CH

The present study observed the effects of a green tea (Camellia sinensis) flower extract (GTFE) on melanin synthesis in B16-F10 melanoma cells. GTFE exhibited antioxidant activity on 2,2-diphenyl-1-picrylhydrazyl and inhibited...
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Artemisia capillaris Thunb. inhibits melanin synthesis activity via ERK-dependent MITF pathway in B16/F10 melanoma cells

Saba E, Oh MJ, Lee YY, Kwak D, Kim S, Rhee MH

Genus Artemisia occurs as a hardy plant and has a wide range of culinary and medicinal features. In this study, we aimed to describe the melanin inhibitory activity of one...
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Melanin extract from Gallus gallus domesticus promotes proliferation and differentiation of osteoblastic MG-63 cells via bone morphogenetic protein-2 signaling

Yoo HS, Chung KH, Lee KJ, Kim DH, An JH

BACKGROUND/OBJECTIVES: Gallus gallus domesticus (GD) is a natural mutant breed of chicken in Korea with an atypical characterization of melanin in its tissue. This study investigated the effects of melanin...
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A Case of Pigmented Epidermal Cyst with Dense Collection of Melanin

Jung J, Lee M, Ha J, Cho E, Park E, Kim K, Kim K

  • KMID: 2359683
  • Korean J Dermatol.
  • 2016 Nov;54(9):751-753.
No abstract available.
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Modulation of Melanin Synthesis by Amaranthus spp. L Seed Extract in Melan-a Cells

Seo JO, Do MH, Lee JH, Lee TH, Wahedi HM, Park YU, Kim SY

Anti-melanogenic effects of amaranth (AT), one of the key source of squalene, were investigated in melanocytes. Amaranth seed powder was extracted with water and melan-a cells were treated with various...
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Analysis of lysosomal membrane proteins exposed to melanin in HeLa cells

Bang SH, Park DJ, Kim YH, Min J

OBJECTIVES: There have been developed to use targeting ability for antimicrobial, anticancerous, gene therapy and cosmetics through analysis of various membrane proteins isolated from cell organelles. METHODS: It was examined about...
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Changes in Melanin and Melanocytes in Mottled Hypopigmentation after Low-Fluence 1,064-nm Q-Switched Nd:YAG Laser Treatment for Melasma

Jang YH, Park JY, Park YJ, Kang HY

No abstract available.
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Resveratrol-Enriched Rice Down-Regulates Melanin Synthesis in UVB-Induced Guinea Pigs Epidermal Skin Tissue

Lee TH, Seo JO, Do MH, Ji E, Baek SH, Kim SY

Synthetic compounds that are used in the clinic to regulate skin hyperpigmentation, such as arbutin, hydroquinone, and kojic acid, are only moderately effective. But, their use is limited by side...
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Scopoletin from Cirsium setidens Increases Melanin Synthesis via CREB Phosphorylation in B16F10 Cells

Ahn MJ, Hur SJ, Kim EH, Lee SH, Shin JS, Kim MK, Uchizono J, Whang WK, Kim DS

In this study, we isolated scopoletin from Cirsium setidens Nakai (Compositae) and tested its effects on melanogenesis. Scopoletin was not toxic to cells at concentrations less than 50 microM and...
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KHG26792 Inhibits Melanin Synthesis in Mel-Ab Cells and a Skin Equivalent Model

Li H, Kim J, Hahn HG, Yun J, Jeong HS, Yun HY, Baek KJ, Kwon NS, Min YS, Park KC, Kim DS

The purpose of this study is to characterize the effects of KHG26792 (3-(naphthalen-2-yl(propoxy) methyl)azetidine hydrochloride), a potential skin whitening agent, on melanin synthesis and identify the underlying mechanism of action....
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Inhibitory Effects of Resveratrol on Melanin Synthesis in Ultraviolet B-Induced Pigmentation in Guinea Pig Skin

Lee TH, Seo JO, Baek SH, Kim SY

  • KMID: 2048328
  • Biomol Ther.
  • 2014 Jan;22(1):35-40.
Resveratrol is a polyphenolic compound found in various natural products such as grapes and berries and possesses anti-cancer, anti-hyperlipidemia, and anti-aging properties. Recently, it has been reported that resveratrol inhibits...
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Skin Organ Culture Model for Evaluation of Melanin Pigmentation

Lee JS, Lee JY, Choi YM, Jung YS, Kang WH, Kang HY

  • KMID: 2302638
  • Korean J Dermatol.
  • 2005 Apr;43(4):450-454.
BACKGROUND: Skin organ culture is widely used as a tool to investigate skin biology or skin disease. OBJECTIVE: The objective of the present study was to develop an ideal skin...
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Melanin Pigmentation In Gingiva

Lee IK, Han SB

Oral melanin pigmentation is common in some races and ethnic groups. The gingivae are the most frequently pigmented intra-oral tissues. Melanin pigmentation is the result of melanin granules, produced by...
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A Study of Skin Color by Melanin Index according to Sex, Age, Site and Skin Phototype in Koreans

Lee MH, Lim TW, Lee MH

BACKGROUND: Skin color is determined by many factors including melanin and nonmelanin pigments like hemoglobin and extraneous chemicals. Various factors such as race, sex, and age have been reported to...
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Melanin Depigmentation by 90% Phenol Application in Canine Gingiva

Jeong TS, Kim YJ, Chung HJ

In this present study, the healing process and the recurrence of pigmentation were evaluated clinically and histologically in accordance with the extent and the range of pigmentation after phenol was...
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Erythema and Melanin Index According to UVB Radiation Doses by Use of a Reflectance Spectrophotometer in Korean Young Adults

Park SB, Kim BK, Eun HC, Youn JI

  • KMID: 2085955
  • Korean J Dermatol.
  • 1997 Aug;35(4):729-735.
BACKGROUND: Methods of estimating the erythema and pigmentation reactions, such as MPE (Minimal Perceptible Erythema), ME(Minimal Erythema Dose) and MMD(Minimal Melanogenic Dose), are vulnerable to the variations of subjective visual...
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UVA Blocking Effect of Epidermal Melanin in Patients with Vitiligo

Lee HR, Kang HC, Hahm JH

BACKGROUND: Ultraviolet light induces sunburn, aging of the skin, disorders of pigment and even promotes skin cancers. Melanin is known to have a protecting role in the skin by blocking...
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The Effect of Supernatant from UVB - Irradiated Cultured Keratinocytes on the Growth , Melanin Content , and Tyrosinase Activity of Human Melanocyte

Kim ST, Suh KS, Chae YS, Jo MY, Cheong IC

  • KMID: 1930760
  • Korean J Dermatol.
  • 1994 Oct;32(5):809-819.
BACKGROUND: Melanin pigment plays a major role in the expression of normal human skin color as well as in the photoprotection against ultraviolet damage. Melanin produced in melanocytes is transferred...
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A Case of Eccrine Poroma Containing Melanin Granules

Joh GY, Lee AY, Youn JI, Lee YS

  • KMID: 1679141
  • Korean J Dermatol.
  • 1985 Feb;23(1):105-108.
It has been generally assumed that eccrine poroma ariees from acroayringium, epidermal sweat duct unit. One of the characteriatics of thie structure is abaence of melanocytes and melanin granules among...
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